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Genetics The Genetics collection covers topics such as BRCA, gene therapy, and gene mutations and polymorphisms and includes research articles, case reports, reviews, and editorial commentary.  Subscribe to the Genetics
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21-40 (of 1095 results)
| Earlier content (since Jan 1996): |
Molecular Origins of Cancer: DNA Damage, Aging, and Cancer
Hoeijmakers J. H.J.
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N Engl J Med 2009;
361:1475-1485, Oct 8, 2009.
Review Articles
Micromanaging Cancer
Lieberman J.
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N Engl J Med 2009;
361:1500-1501, Oct 8, 2009.
Editorials
Rendering the Leukemia Cell Susceptible to Attack
Sipkins D. A.
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N Engl J Med 2009;
361:1307-1309, Sep 24, 2009.
Clinical Implications of Basic Research
Combined Immunodeficiency Associated with DOCK8 Mutations
Zhang Q., Davis J. C., Lamborn I. T., Freeman A. F., Jing H., Favreau A. J., Matthews H. F., Davis J., Turner M. L., Uzel G., Holland S. M., Su H. C.
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N Engl J Med 2009;
published at www.nejm.org on
Sep 23, 2009
(10.1056/NEJMoa0905506).
Original Articles
Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men
Ding E. L., Song Y., Manson J. E., Hunter D. J., Lee C. C., Rifai N., Buring J. E., Gaziano J. M., Liu S.
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N Engl J Med 2009;
361:1152-1163, Sep 17, 2009;
published at www.nejm.org on Aug 5, 2009 (10.1056/NEJMoa0804381).
Original Articles
Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
Von Hoff D. D., LoRusso P. M., Rudin C. M., Reddy J. C., Yauch R. L., Tibes R., Weiss G. J., Borad M. J., Hann C. L., Brahmer J. R., Mackey H. M., Lum B. L., Darbonne W. C., Marsters J. C. Jr., de Sauvage F. J., Low J. A.
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N Engl J Med 2009;
361:1164-1172, Sep 17, 2009;
published at www.nejm.org on Sep 2, 2009 (10.1056/NEJMoa0905360).
Original Articles
Brief Report:Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
Rudin C. M., Hann C. L., Laterra J., Yauch R. L., Callahan C. A., Fu L., Holcomb T., Stinson J., Gould S. E., Coleman B., LoRusso P. M., Von Hoff D. D., de Sauvage F. J., Low J. A.
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N Engl J Med 2009;
361:1173-1178, Sep 17, 2009;
published at www.nejm.org on Sep 2, 2009 (10.1056/NEJMoa0902903).
Original Articles
Following the Hedgehog to New Cancer Therapies
Dlugosz A. A., Talpaz M.
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N Engl J Med 2009;
361:1202-1205, Sep 17, 2009;
published at www.nejm.org on Sep 2, 2009 (10.1056/NEJMe0906092).
Editorials
Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
Mardis E. R., Ding L., Dooling D. J., Larson D. E., McLellan M. D., Chen K., Koboldt D. C., Fulton R. S., Delehaunty K. D., McGrath S. D., Fulton L. A., Locke D. P., Magrini V. J., Abbott R. M., Vickery T. L., Reed J. S., Robinson J. S., Wylie T., Smith S. M., Carmichael L., Eldred J. M., Harris C. C., Walker J., Peck J. B., Du F., Dukes A. F., Sanderson G. E., Brummett A. M., Clark E., McMichael J. F., Meyer R. J., Schindler J. K., Pohl C. S., Wallis J. W., Shi X., Lin L., Schmidt H., Tang Y., Haipek C., Wiechert M. E., Ivy J. V., Kalicki J., Elliott G., Ries R. E., Payton J. E., Westervelt P., Tomasson M. H., Watson M. A., Baty J., Heath S., Shannon W. D., Nagarajan R., Link D. C., Walter M. J., Graubert T. A., DiPersio J. F., Wilson R. K., Ley T. J.
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N Engl J Med 2009;
361:1058-1066, Sep 10, 2009;
published at www.nejm.org on Aug 5, 2009 (10.1056/NEJMoa0903840).
Original Articles
Case 28-2009 — A 68-Year-Old Man with Fatigue, Cough, and Peripheral-Blood Monocytosis
Dey B. R., Spitzer T. R., Hasserjian R. P.
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CME Exam
N Engl J Med 2009;
361:1099-1106, Sep 10, 2009.
Case Records of the Massachusetts General Hospital
Cancer Genomes — Continuing Progress
Downing J. R.
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N Engl J Med 2009;
361:1111-1112, Sep 10, 2009;
published at www.nejm.org on Aug 5, 2009 (10.1056/NEJMe0906090).
Editorials
Understanding Abdominal Aortic Aneurysm
Weintraub N. L.
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N Engl J Med 2009;
361:1114-1116, Sep 10, 2009.
Clinical Implications of Basic Research
Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
Mok T. S., Wu Y.-L., Thongprasert S., Yang C.-H., Chu D.-T., Saijo N., Sunpaweravong P., Han B., Margono B., Ichinose Y., Nishiwaki Y., Ohe Y., Yang J.-J., Chewaskulyong B., Jiang H., Duffield E. L., Watkins C. L., Armour A. A., Fukuoka M.
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N Engl J Med 2009;
361:947-957, Sep 3, 2009;
published at www.nejm.org on Aug 19, 2009 (10.1056/NEJMoa0810699).
Original Articles
Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer
Rosell R., Moran T., Queralt C., Porta R., Cardenal F., Camps C., Majem M., Lopez-Vivanco G., Isla D., Provencio M., Insa A., Massuti B., Gonzalez-Larriba J. L., Paz-Ares L., Bover I., Garcia-Campelo R., Moreno M. A., Catot S., Rolfo C., Reguart N., Palmero R., Sánchez J. M., Bastus R., Mayo C., Bertran-Alamillo J., Molina M. A., Sanchez J. J., Taron M., the Spanish Lung Cancer Group
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N Engl J Med 2009;
361:958-967, Sep 3, 2009;
published at www.nejm.org on Aug 19, 2009 (10.1056/NEJMoa0904554).
Original Articles
Personalized Medicine and Inhibition of EGFR Signaling in Lung Cancer
Gazdar A. F.
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N Engl J Med 2009;
361:1018-1020, Sep 3, 2009;
published at www.nejm.org on Aug 19, 2009 (10.1056/NEJMe0905763).
Editorials
Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
Von Hoff D. D., LoRusso P. M., Rudin C. M., Reddy J. C., Yauch R. L., Tibes R., Weiss G. J., Borad M. J., Hann C. L., Brahmer J. R., Mackey H. M., Lum B. L., Darbonne W. C., Marsters J. C. Jr., de Sauvage F. J., Low J. A.
Abstract |
Full Text |
PDF
N Engl J Med 2009;
published at www.nejm.org on
Sep 2, 2009
(10.1056/NEJMoa0905360).
Original Articles
Brief Report:Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
Rudin C. M., Hann C. L., Laterra J., Yauch R. L., Callahan C. A., Fu L., Holcomb T., Stinson J., Gould S. E., Coleman B., LoRusso P. M., Von Hoff D. D., de Sauvage F. J., Low J. A.
Summary |
Full Text |
PDF
N Engl J Med 2009;
published at www.nejm.org on
Sep 2, 2009
(10.1056/NEJMoa0902903).
Original Articles
Following the Hedgehog to New Cancer Therapies
Dlugosz A. A., Talpaz M.
Extract |
Full Text |
PDF
N Engl J Med 2009;
published at www.nejm.org on
Sep 2, 2009
(10.1056/NEJMe0906092).
Editorials
Finding the Weakness in Cancer
Downward J.
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N Engl J Med 2009;
361:922-924, Aug 27, 2009.
Clinical Implications of Basic Research
Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer
Rosell R., Moran T., Queralt C., Porta R., Cardenal F., Camps C., Majem M., Lopez-Vivanco G., Isla D., Provencio M., Insa A., Massuti B., Gonzalez-Larriba J. L., Paz-Ares L., Bover I., Garcia-Campelo R., Moreno M. A., Catot S., Rolfo C., Reguart N., Palmero R., Sánchez J. M., Bastus R., Mayo C., Bertran-Alamillo J., Molina M. A., Sanchez J. J., Taron M., the Spanish Lung Cancer Group
Abstract |
Full Text |
PDF
N Engl J Med 2009;
published at www.nejm.org on
Aug 19, 2009
(10.1056/NEJMoa0904554).
Original Articles
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