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Figure 1. PCR Analysis of the A1226G (N370S) Mutation in Patients with Parkinson's Disease.
When the mutation is present (lanes 1, 4, and 7), the enzyme (XhoI) digests a 105-bp PCR product, producing two fragments of 89 and 16 bp. The wild-type PCR product remains uncut (lanes 2, 3, 5, and 6). M denotes a 50-bp marker.