Multifactorial Intervention in Patients with Type 2 Diabetes and Microalbuminuria
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Cardiovascular morbidity remains a major problem among patients with type 2 diabetes, especially those with microalbuminuria. These authors compared conventional therapy with intensive treatment involving a stepwise implementation of behavior modification and pharmacologic therapy to target hyperglycemia, hypertension, dyslipidemia, microalbuminuria, and secondary prevention of cardiovascular disease in an open, parallel trial.
Targeted, intensified, long-term intervention aimed at multiple risk factors in patients with type 2 diabetes reduced cardiovascular and microvascular events by half, indicating that this approach works well over time.