The electrocardiographic response to exercise was compared with the results of coronary angiography in 89 patients with Type II hyperlipoproteinemia who had previous myocardial infarction or typical angina or both (43 patients)(Group A), "atypical angina" (16 patients)(Group B)or positive electrocardiographic response to exercise without other evidence of cardiac disease (30 patients)(Group C). Thirty-nine of 43 in Group A had greater than or equal to 50 per cent stenosis, and 26 (67%) of these 39 had negative exercise tests. In Group B, five of the 16 had greater than or equal to 50% stenosis, and three had positive exercise tests (one patient had a false-positive test). In Group C, eleven of 30(37%) had greater than or equal to 50% stenosis; however, nine (30%) had minor stenosis (less than or equal to 50%), and 10(33%) normal coronary arteries. The diagnostic usefulness of exercise electrocardiography is limited. False-negative responses are frequent in patients with clinically suspected coronary disease, and false-positive responses frequent in asymptomatic patients.
This article has been cited by other articles:
Kligfield, P., Lauer, M. S.
(2006). Exercise Electrocardiogram Testing: Beyond the ST Segment. Circulation
114: 2070-2082
[Full Text]
Turkmen, M., Barutcu, I., Esen, A. M., Karakaya, O., Esen, O., Basaran, Y.
(2005). Exercise-Induced QRS Amplitude Changes in Patients with Isolated Myocardial Bridging: A Marker of Myocardial Ischemia. ANGIOLOGY
56: 265-271
[Abstract]
Sekiya, M., Suzuki, M., Fujiwara, Y., Sumimoto, T., Hamada, M., Hiwada, K.
(1992). Hemodynamic Characteristics of Patients with Coronary Artery Disease Presenting False-Negative Exercise Stress Test. ANGIOLOGY
43: 506-511
[Abstract]
Beitman, B. D., Basha, I., Flaker, G., DeRosear, L., Mukerji, V., Trombka, L., Katon, W.
(1987). Atypical or Nonanginal Chest Pain: Panic Disorder or Coronary Artery Disease?. Arch Intern Med
147: 1548-1552
[Abstract]
ARMSTRONG, W. F., O'DONNELL, J., DILLON, J. C., McHENRY, P. L., MORRIS, S. N., FEIGENBAUM, H.
(1986). Complementary Value of Two-Dimensional Exercise Echocardiography to Routine Treadmill Exercise Testing. ANN INTERN MED
105: 829-835
[Abstract]
Engelberg, A. L., Gibbons, H. L., Doege, T. C.
(1986). A Review of the Medical Standards for Civilian Airmen: Synopsis of a Two-Year Study. JAMA
255: 1589-1599
[Abstract]
LEIGHTON, R. F., FRAKER, T. D. JR.
(1984). Silent Myocardial Ischemia: Concern Is Justified for the Patient with Known Coronary Artery Disease. ANN INTERN MED
100: 599-601
[Abstract]
McGuire, L. B.
(1981). The Uses and Limits of Standard Exercise Tests. Arch Intern Med
141: 229-232
[Abstract]
Ikram, H., Chan, W.C., Bones, P.J., Sherry, E.
(1980). Factors Influencing the Diagnostic Sensitivity of the Exercise Test in Coronary Artery Disease. ANGIOLOGY
31: 246-253
Michelson, E. L., Morganroth, J., Nichols, C. W., MacVaugh, H. III
(1979). Retinal Arteriolar Changes as an Indicator of Coronary Artery Disease. Arch Intern Med
139: 1139-1141
[Abstract]
CRAWFORD, M. H., MENDOZA, C. A., O'ROURKE, R. A., WHITE, D. H., BOUCHER, C. A., GORWIT, J.
(1978). Limitations of Continuous Ambulatory Electrocardiogram Monitoring for Detecting Coronary Artery Disease. ANN INTERN MED
89: 1-5
[Abstract]
Crawford, M. H.
(1977). New Approaches To Resolving Diagnostic Problems in Patients With Angina Pectoris. ANGIOLOGY
28: 142-148
