FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 302:769-771 April 3, 1980 Number 14 Next

	Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Abstract

An abnormally low sodium-potassium net flux ratio in erythrocytes was recently described in human essential hypertension. We have confirmed this finding in 65 patients with essential hypertension who were compared with 33 normotensive controls born of normotensive parents. In 23 other subjects with documented secondary hypertension and normotensive parents, the sodium-potassium net flux ratio was found to be similar to that in the controls. The erythrocyte test thus appears to be of interest in distinguishing between essential and secondary hypertension. Severe renal failure itself reduces the flux ratio and would therefore distort the results of this test.

This article has been cited by other articles:

• Weir, M. R., Chrysant, S. G., McCarron, D. A., Canossa-Terris, M., Cohen, J. D., Gunter, P. A., Lewin, A. J., Mennella, R. F., Kirkegaard, L. W., Hamilton, J. H., Weinberger, M. H., Weder, A. B. (1998). Influence of Race and Dietary Salt on the Antihypertensive Efficacy of an Angiotensin-Converting Enzyme Inhibitor or a Calcium Channel Antagonist in Salt-Sensitive Hypertensives. Hypertension 31: 1088-1096 [Abstract] [Full Text]  
• Andronico, G., Ferrara, L., Mangano, M., Mule, G., Cerasola, G. (1998). Insulin, Sodium-Lithium Countertransport, and Microalbuminuria in Hypertensive Patients. Hypertension 31: 110-113 [Abstract] [Full Text]