This report describes a catheter technique for ablating the His bundle and its application in nine patients with recurrent supraventricular tachycardia that was unresponsive to medical management. A tripolar electrode catheter was positioned in the region of the His bundle, and the electrode recording a large unipolar His-bundle potential was identified. In the first patient, two shocks of 25 and 50 J, respectively, were delivered by a standard cardioversion unit to the catheter electrode, resulting in an intra-His-bundle conduction defect. Subsequent delivery of 300 J resulted in complete heart block. In the next eight patients, an initial shock of 200 J was used. The His bundle was ablated by this single shock in six of these patients and by an additional shock of 300 J in one. In the remaining patient, conduction in the atrioventricular node was modified, resulting in alternating first and second-degree atrioventricular block. A stable escape rhythm was preserved in all patients. The procedure was well tolerated, without complications, and all patients have remained free of arrhythmia, without medication, for follow-up periods of two to six months.
This article has been cited by other articles:
Epstein, A. E., DiMarco, J. P., Ellenbogen, K. A., Estes, N.A. M. III, Freedman, R. A., Gettes, L. S., Gillinov, A. M., Gregoratos, G., Hammill, S. C., Hayes, D. L., Hlatky, M. A., Newby, L. K., Page, R. L., Schoenfeld, M. H., Silka, M. J., Stevenson, L. W., Sweeney, M. O.
(2008). ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) Developed in Collaboration With the American Association for Thoracic Surgery and Society of Thoracic Surgeons. J Am Coll Cardiol
51: e1-e62
[Full Text]
Epstein, A. E., DiMarco, J. P., Ellenbogen, K. A., Mark Estes, N.A. III, Freedman, R. A., Gettes, L. S., Gillinov, A. M., Gregoratos, G., Hammill, S. C., Hayes, D. L., Hlatky, M. A., Newby, L. K., Page, R. L., Schoenfeld, M. H., Silka, M. J., Stevenson, L. W., Sweeney, M. O.
(2008). ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) Developed in Collaboration With the American Association for Thoracic Surgery and Society of Thoracic Surgeons. J Am Coll Cardiol
51: 2085-2105
[Full Text]
Epstein, A. E., DiMarco, J. P., Ellenbogen, K. A., Estes, N.A. M. III, Freedman, R. A., Gettes, L. S., Gillinov, A. M., Gregoratos, G., Hammill, S. C., Hayes, D. L., Hlatky, M. A., Newby, L. K., Page, R. L., Schoenfeld, M. H., Silka, M. J., Stevenson, L. W., Sweeney, M. O.
(2008). ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): Developed in Collaboration With the American Association for Thoracic Surgery and Society of Thoracic Surgeons. Circulation
117: 2820-2840
[Full Text]
Epstein, A. E., DiMarco, J. P., Ellenbogen, K. A., Estes, N.A. M. III, Freedman, R. A., Gettes, L. S., Gillinov, A. M., Gregoratos, G., Hammill, S. C., Hayes, D. L., Hlatky, M. A., Newby, L. K., Page, R. L., Schoenfeld, M. H., Silka, M. J., Stevenson, L. W., Sweeney, M. O.
(2008). ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): Developed in Collaboration With the American Association for Thoracic Surgery and Society of Thoracic Surgeons. Circulation
117: e350-e408
[Full Text]
Wellens, H. J.
(2008). Forty Years of Invasive Clinical Electrophysiology: 1967-2007. Circ Arrhythmia Electrophysiol
1: 49-53
[Full Text]
Betts, T. R.
(2008). Atrioventricular junction ablation and pacemaker implant for atrial fibrillation: still a valid treatment in appropriately selected patients. Europace
10: 425-432
[Abstract][Full Text]
Eckart, R. E., Epstein, L. M.
(2008). Interventional Therapy for Atrial and Ventricular Arrhythmias. Card Surg Adult
3: 1357-1374
[Full Text]
Sutton, R., Fisher, J. D., Linde, C., Benditt, D. G.
(2007). History of electrical therapy for the heart. Eur Heart J Suppl
9: I3-I10
[Abstract][Full Text]
Wolpert, C., Pitschner, H., Borggrefe, M.
(2007). Evolution of ablation techniques: from WPW to complex arrhythmias. Eur Heart J Suppl
9: I116-I121
[Abstract][Full Text]
Authors/Task Force Members, , Vardas, P. E., Auricchio, A., Blanc, J.-J., Daubert, J.-C., Drexler, H., Ector, H., Gasparini, M., Linde, C., Morgado, F. B., Oto, A., Sutton, R., Trusz-Gluza, M., ESC Committee for Practice Guidelines (CPG), , Vahanian, A., Camm, J., De Caterina, R., Dean, V., Dickstein, K., Funck-Brentano, C., Filippatos, G., Hellemans, I., Kristensen, S. D., McGregor, K., Sechtem, U., Silber, S., Tendera, M., Widimsky, P., Zamorano, J. L., Document Reviewers, , Priori, S. G., Blomstrom-Lundqvist, C., Brignole, M., Terradellas, J. B., Camm, J., Castellano, P., Cleland, J., Farre, J., Fromer, M., Le Heuzey, J.-Y., Lip, G. Y., Merino, J. L., Montenero, A. S., Ritter, P., Schalij, M. J., Stellbrink, C.
(2007). Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in Collaboration with the European Heart Rhythm Association. Europace
9: 959-998
[Full Text]
Authors/Task Force Members, , Vardas, P. E., Auricchio, A., Blanc, J.-J., Daubert, J.-C., Drexler, H., Ector, H., Gasparini, M., Linde, C., Morgado, F. B., Oto, A., Sutton, R., Trusz-Gluza, M., ESC Committee for Practice Guidelines (CPG), , Vahanian, A., Camm, J., De Caterina, R., Dean, V., Dickstein, K., Funck-Brentano, C., Filippatos, G., Hellemans, I., Kristensen, S. D., McGregor, K., Sechtem, U., Silber, S., Tendera, M., Widimsky, P., Zamorano, J. L., Document Reviewers, , Priori, S. G., Blomstrom-Lundqvist, C., Brignole, M., Terradellas, J. B., Camm, J., Castellano, P., Cleland, J., Farre, J., Fromer, M., Le Heuzey, J.-Y., Lip, G. Y., Merino, J. L., Montenero, A. S., Ritter, P., Schalij, M. J., Stellbrink, C.
(2007). Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in Collaboration with the European Heart Rhythm Association. Eur Heart J
28: 2256-2295
[Full Text]
Tracy, C. M., Akhtar, M., DiMarco, J. P., Packer, D. L., Weitz, H. H., Creager, M. A., Holmes, D. R. Jr, Merli, G., Rodgers, G. P., Tracy, C. M., Weitz, H. H.
(2006). American College of Cardiology/American Heart Association 2006 Update of the Clinical Competence Statement on Invasive Electrophysiology Studies, Catheter Ablation, and Cardioversion: A Report of the American College of Cardiology/American Heart Association/American College of Physicians Task Force on Clinical Competence and Training Developed in Collaboration With the Heart Rhythm Society. J Am Coll Cardiol
48: 1503-1517
[Full Text]
Wellens, H. J.J.
(2004). Cardiac arrhythmias: The quest for a cure: A historical perspective. J Am Coll Cardiol
44: 1155-1163
[Abstract][Full Text]
Sie, H. T, Beukema, W. P, Elvan, A., Ramdat Misier, A. R
(2003). New strategies in the surgical treatment of atrial fibrillation. Cardiovasc Res
58: 501-509
[Abstract][Full Text]
Satti, S. D., Epstein, L. M.
(2003). Cardiologic Interventional Therapy for Atrial and Ventricular Arrhythmias. Card Surg Adult
2: 1253-1270
[Full Text]
Committee Members, , Gregoratos, G., Abrams, J., Epstein, A. E., Freedman, R. A., Hayes, D. L., Hlatky, M. A., Kerber, R. E., Naccarelli, G. V., Schoenfeld, M. H., Silka, M. J., Winters, S. L., Task Force Members, , Gibbons, R. J., Antman, E. M., Alpert, J. S., Gregoratos, G., Hiratzka, L. F., Faxon, D. P., Jacobs, A. K., Fuster, V., Smith, S. C. Jr.
(2002). ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices--Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines) . J Am Coll Cardiol
40: 1703-1719
[Full Text]
Gregoratos, G., Abrams, J., Epstein, A. E., Freedman, R. A., Hayes, D. L., Hlatky, M. A., Kerber, R. E., Naccarelli, G. V., Schoenfeld, M. H., Silka, M. J., Winters, S. L., Gibbons, R. J., Antman, E. M., Alpert, J. S., Gregoratos, G., Hiratzka, L. F., Faxon, D. P., Jacobs, A. K., Fuster, V., Smith, S. C. Jr, Committee Members, , Task Force Members,
(2002). ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices: Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines). Circulation
106: 2145-2161
[Full Text]
Blaauw, Y, Van Gelder, I C, Crijns, H J G M
(2002). Treatment of atrial fibrillation. Heart
88: 432-437
[Full Text]
Tracy, C. M., Akhtar, M., DiMarco, J. P., Packer, D. L., Weitz, H. H., Winters, W. L., Achord, J. L., Boone, A. W., Hirshfeld, J. W. Jr, Lorell, B. H., Rodgers, G. P., Tracy, C. M., Weitz, H. H.
(2000). American College of Cardiology/American Heart Association Clinical Competence Statement on invasive electrophysiology studies, catheter ablation, and cardioversion: A report of the american college of cardiology/american heart association/american college of physicians-american society of internal medicine task force on clinical competence. J Am Coll Cardiol
36: 1725-1736
[Full Text]
Tracy, C. M., Akhtar, M., DiMarco, J. P., Packer, D. L., Weitz, H. H., Winters, W. L., Achord, J. L., Boone, A. W., Hirshfeld, J. W. Jr, Lorell, B. H., Rodgers, G. P., Tracy, C. M., Weitz, H. H.
(2000). American College of Cardiology/American Heart Association Clinical Competence Statement on Invasive Electrophysiology Studies, Catheter Ablation, and Cardioversion : A Report of the American College of Cardiology/American Heart Association/American College of Physicians-American Society of Internal Medicine Task Force on Clinical Competence. Circulation
102: 2309-2320
[Full Text]
Lardo, A. C., McVeigh, E. R., Jumrussirikul, P., Berger, R. D., Calkins, H., Lima, J., Halperin, H. R.
(2000). Visualization and Temporal/Spatial Characterization of Cardiac Radiofrequency Ablation Lesions Using Magnetic Resonance Imaging. Circulation
102: 698-705
[Abstract][Full Text]
Morady, F.
(1999). Radio-Frequency Ablation as Treatment for Cardiac Arrhythmias. NEJM
340: 534-544
[Full Text]
Levy, S.
(1999). Atrioventricular junctional ablation and pacing for paroxysmal atrial fibrillation: the Barcelona recommendations. Europace
1: 2-4
Marshall, H. J., Griffith, M. J.
(1999). Ablation of the atrioventricular junction: Technique, acute and long-term results in 115 consecutive patients. Europace
1: 26-29
[Abstract]
Wellens, H. J. J., Lau, C.-P., Luderitz, B., Akhtar, M., Waldo, A. L., Camm, A. J., Timmermans, C., Tse, H.-F., Jung, W., Jordaens, L., Ayers, G., Investigators, f. t. M.
(1998). Atrioverter: An Implantable Device for the Treatment of Atrial Fibrillation. Circulation
98: 1651-1656
[Abstract][Full Text]
Gepstein, L., Hayam, G., Ben-Haim, S. A.
(1997). A Novel Method for Nonfluoroscopic Catheter-Based Electroanatomical Mapping of the Heart : In Vitro and In Vivo Accuracy Results. Circulation
95: 1611-1622
[Abstract][Full Text]
Chen, S.-A., Lee, S.-H., Chiang, C.-E., Tai, C.-T., Wu, T.-J., Cheng, C.-C., Wen, Z.-C., Chiou, C.-W., Ueng, K.-C., Chang, M.-S.
(1996). Electrophysiological Mechanisms in Successful Radiofrequency Catheter Modification of Atrioventricular Junction for Patients With Medically Refractory Paroxysmal Atrial Fibrillation. Circulation
93: 1690-1701
[Abstract][Full Text]
Prystowsky, E. N., Benson, D. W. Jr, Fuster, V., Hart, R. G., Kay, G. N., Myerburg, R. J., Naccarelli, G. V., Wyse, D. G.
(1996). Management of Patients With Atrial Fibrillation : A Statement for Healthcare Professionals From the Subcommittee on Electrocardiography and Electrophysiology, American Heart Association. Circulation
93: 1262-1277
[Full Text]
Alison, J. F., Yeung-Lai-Wah, J. A., Schulzer, M., Kerr, C. R.
(1995). Characterization of Junctional Rhythm After Atrioventricular Node Ablation. Circulation
91: 84-90
[Abstract][Full Text]
Williamson, B. D., Man, K. C., Daoud, E., Niebauer, M., Strickberger, S. A., Morady, F.
(1994). Radiofrequency Catheter Modification of Atrioventricular Conduction to Control the Ventricular Rate during Atrial Fibrillation. NEJM
331: 910-917
[Abstract][Full Text]
Wellens, H. J.J.
(1994). Atrial Fibrillation -- The Last Big Hurdle in Treating Supraventricular Tachycardia. NEJM
331: 944-945
[Full Text]
Nalos, P. C., Myers, M. R., Gang, E. S., Peter, T., Mandel, W. J.
(1987). Analytic Reviews: Electrophysiologic Testing in the Intensive Care Unit. J Intensive Care Med
2: 241-259
[Abstract]
Herre, J. M.
(1987). Advances in the Management of Tachyarrhythmias. J Intensive Care Med
2: 65-75
[Abstract]