We describe a simple bedside procedure (which we call "Osler's maneuver") that differentiates patients with true hypertension from those whose blood pressure is spuriously elevated because of excessive sclerosis of the large arteries ("pseudohypertension"). The maneuver is performed by assessing the palpability of the pulseless radial or brachial artery distal to a point of occlusion of the artery manually or by cuff pressure. We classified 24 elderly hypertensive patients as either Osler-positive (n = 13) or Osler-negative (n = 11), and measured their intraarterial pressure, arterial compliance, and systemic hemodynamics. Patients with pseudohypertension (Osler-positive) had falsely elevated blood-pressure readings, with a difference of 10 to 54 mm Hg between cuff and intraarterial pressure. Arterial compliance was lower in Osler-positive subjects and correlated with the difference between cuff and intraarterial pressures, indicating that the stiffer the artery, the more pronounced the degree of pseudohypertension. Pseudohypertension is common in the elderly and becomes more severe as arterial compliance decreases and sclerosis of large arteries progresses.
This article has been cited by other articles:
KATAKAM, R., BRUKAMP, K., TOWNSEND, R. R.
(2008). What is the proper workup of a patient with hypertension?. Cleveland Clinic Journal of Medicine
75: 663-672
[Abstract][Full Text]
Moser, M., Setaro, J. F.
(2006). Clinical practice. Resistant or difficult-to-control hypertension.. NEJM
355: 385-392
[Full Text]
Papadopoulos, D. P., Papademetriou, V.
(2006). Resistant Hypertension: Diagnosis and Management. J CARDIOVASC PHARMACOL THER
11: 113-118
[Abstract]
Elliott, H. L, McInnes, G. T
(2002). Special management needs of the elderly hypertensive patient. Journal of Renin-Angiotensin-Aldosterone System
3: S25-S31
Lu, F.-H., Tang, S.-J., Wu, J.-S., Yang, Y.-C., Chang, C.-J.
(2000). Hypertension in Elderly Persons: Its Prevalence and Associated Cardiovascular Risk Factors in Tainan City, Southern Taiwan. J. Gerontol. A Biol. Sci. Med. Sci.
55: 463M-468
[Abstract][Full Text]
Vardan, S., Mookherjee, S.
(2000). Perspectives on Isolated Systolic Hypertension in Elderly Patients. Arch Fam Med
9: 319-323
[Abstract][Full Text]
Castellani, S., Ungar, A., Cantini, C., La Cava, G., Di Serio, C., Vallotti, B., Altobelli, A., Masotti, G.
(1999). Impaired Renal Adaptation to Stress in the Elderly With Isolated Systolic Hypertension. Hypertension
34: 1106-1111
[Abstract][Full Text]
Cheng, T. O., Chae, C., Pfeffer, M.
(1999). Osler Maneuver to Detect Pseudohypertension. JAMA
282: 943-943
[Full Text]
Blank, S. G., Mann, S. J., James, G. D., West, J. E., Pickering, T. G.
(1995). Isolated Elevation of Diastolic Blood Pressure : Real or Artifactual?. Hypertension
26: 383-389
[Abstract][Full Text]
Messerli, F. H.
(1995). This Day 50 Years Ago. NEJM
332: 1038-1039
[Full Text]
Safar, M.E., St. Laurent, , Asmar, R.E., Safavian, A., London, G.M.
(1987). Systolic Hypertension in Patients with Arteriosclerosis Obliterans of the Lower Limbs. ANGIOLOGY
38: 287-295
[Abstract]