We assessed the quality of life of 859 patients undergoing dialysis or transplantation, with the goal of ascertaining whether objective and subjective measures of the quality of life were influenced by case mix or treatment. We found that 79.1 per cent of the transplant recipients were able to function at nearly normal levels, as compared with between 47.5 and 59.1 per cent of the patients treated with dialysis (depending on the type). Nearly 75 per cent of the transplant recipients were able to work, as compared with between 24.7 and 59.3 per cent of the patients undergoing dialysis. On three subjective measures (life satisfaction, well-being, and psychological affect) transplant recipients had a higher quality of life than patients on dialysis. Among the patients treated with dialysis, those undergoing treatment at home had the highest quality of life. All quality-of-life differences were found to persist even after the patient case mix had been controlled statistically. Finally, the quality of life of transplant recipients compared well with that of the general population, but despite favorable subjective assessments, patients undergoing dialysis did not work or function at the same level as people in the general population.
This article has been cited by other articles:
Vamos, E. P., Csepanyi, G., Zambo, M., Molnar, M. Z., Rethelyi, J., Kovacs, A., Marton, A., Nemeth, Z., Novak, M., Mucsi, I.
(2008). Sociodemographic factors and patient perceptions are associated with attitudes to kidney transplantation among haemodialysis patients. Nephrol Dial Transplant
0: gfn660v1-gfn660
[Abstract][Full Text]
Spiegel, D. M., Evans, R. W., Gitlin, M., Mayne, T. J.
(2008). Psychometric evaluation of the National Kidney Dialysis and Kidney Transplantation Study symptom checklist: reliability and validity. Nephrol Dial Transplant
0: gfn523v1-gfn523
[Abstract][Full Text]
Vo, A. A., Lukovsky, M., Toyoda, M., Wang, J., Reinsmoen, N. L., Lai, C.-H., Peng, A., Villicana, R., Jordan, S. C.
(2008). Rituximab and Intravenous Immune Globulin for Desensitization during Renal Transplantation. NEJM
359: 242-251
[Abstract][Full Text]
Matas, A. J
(2008). Should we pay donors to increase the supply of organs for transplantation? Yes. BMJ
336: 1342-1342
[Full Text]
Kutner, N., Bowles, T., Zhang, R., Huang, Y., Pastan, S.
(2008). Dialysis Facility Characteristics and Variation in Employment Rates: A National Study. CJASN
3: 111-116
[Abstract][Full Text]
Cohen, S. D., Patel, S. S., Khetpal, P., Peterson, R. A., Kimmel, P. L.
(2007). Pain, Sleep Disturbance, and Quality of Life in Patients with Chronic Kidney Disease. CJASN
2: 919-925
[Abstract][Full Text]
Weisbord, S. D., Fried, L. F., Mor, M. K., Resnick, A. L., Unruh, M. L., Palevsky, P. M., Levenson, D. J., Cooksey, S. H., Fine, M. J., Kimmel, P. L., Arnold, R. M.
(2007). Renal Provider Recognition of Symptoms in Patients on Maintenance Hemodialysis. CJASN
2: 960-967
[Abstract][Full Text]
Weisbord, S. D., Fried, L. F., Unruh, M. L., Kimmel, P. L., Switzer, G. E., Fine, M. J., Arnold, R. M.
(2007). Associations of race with depression and symptoms in patients on maintenance haemodialysis. Nephrol Dial Transplant
22: 203-208
[Abstract][Full Text]
Lindsay, R. M., Heidenheim, P. A., Nesrallah, G., Garg, A. X., Suri, R., on behalf of the Daily Hemodialysis Study Group Lo,
(2006). Minutes to Recovery after a Hemodialysis Session: A Simple Health-Related Quality of Life Question That Is Reliable, Valid, and Sensitive to Change. CJASN
1: 952-959
[Abstract][Full Text]
Wikstrom, B., Gellert, R., Ladefoged, S. D., Danda, Y., Akai, M., Ide, K., Ogasawara, M., Kawashima, Y., Ueno, K., Mori, A., Ueno, Y.
(2005). {kappa}-Opioid System in Uremic Pruritus: Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Studies. J. Am. Soc. Nephrol.
16: 3742-3747
[Abstract][Full Text]
Nolan, C. R.
(2005). Strategies for Improving Long-Term Survival in Patients with ESRD. J. Am. Soc. Nephrol.
16: S120-S127
[Abstract][Full Text]
Matas, A. J., Sutherland, D. E. R.
(2005). The Importance of Innovative Efforts to Increase Organ Donation. JAMA
294: 1691-1693
[Full Text]
Kutner, N. G., Zhang, R., Barnhart, H., Collins, A. J.
(2005). Health status and quality of life reported by incident patients after 1 year on haemodialysis or peritoneal dialysis. Nephrol Dial Transplant
20: 2159-2167
[Abstract][Full Text]
Vincenti, F., Larsen, C., Durrbach, A., Wekerle, T., Nashan, B., Blancho, G., Lang, P., Grinyo, J., Halloran, P. F., Solez, K., Hagerty, D., Levy, E., Zhou, W., Natarajan, K., Charpentier, B., the Belatacept Study Group,
(2005). Costimulation Blockade with Belatacept in Renal Transplantation. NEJM
353: 770-781
[Abstract][Full Text]
Weisbord, S. D., Fried, L. F., Arnold, R. M., Fine, M. J., Levenson, D. J., Peterson, R. A., Switzer, G. E.
(2005). Prevalence, Severity, and Importance of Physical and Emotional Symptoms in Chronic Hemodialysis Patients. J. Am. Soc. Nephrol.
16: 2487-2494
[Abstract][Full Text]
Ortega, T., Ortega, F., Diaz-Corte, C., Rebollo, P., Ma Baltar, J., Alvarez-Grande, J.
(2005). The timely construction of arteriovenous fistulae: a key to reducing morbidity and mortality and to improving cost management. Nephrol Dial Transplant
20: 598-603
[Abstract][Full Text]
Hirshberg, B., Rother, K. I., Digon, B. J. III, Lee, J., Gaglia, J. L., Hines, K., Read, E. J., Chang, R., Wood, B. J., Harlan, D. M.
(2003). Benefits and Risks of Solitary Islet Transplantation for Type 1 Diabetes Using Steroid-Sparing Immunosuppression: The National Institutes of Health experience. Diabetes Care
26: 3288-3295
[Abstract][Full Text]
Kooistra, M. P.
(2003). Frequent prolonged home haemodialysis: three old concepts, one modern solution. Nephrol Dial Transplant
18: 16-18
[Full Text]
Griva, K., Ziegelmann, J. P., Thompson, D., Jayasena, D., Davenport, A., Harrison, M., Newman, S. P.
(2002). Quality of life and emotional responses in cadaver and living related renal transplant recipients. Nephrol Dial Transplant
17: 2204-2211
[Abstract][Full Text]
Goyal, M., Mehta, R. L., Schneiderman, L. J., Sehgal, A. R.
(2002). Economic and Health Consequences of Selling a Kidney in India. JAMA
288: 1589-1593
[Abstract][Full Text]
Sanner, B. M., Tepel, M., Esser, M., Klewer, J., Hoehmann-Riese, B., Zidek, W., Hellmich, B.
(2002). Sleep-related breathing disorders impair quality of life in haemodialysis recipients. Nephrol Dial Transplant
17: 1260-1265
[Abstract][Full Text]
Stack, A. G.
(2002). Determinants of Modality Selection among Incident US Dialysis Patients: Results from a National Study. J. Am. Soc. Nephrol.
13: 1279-1287
[Abstract][Full Text]
LANZETTA, M., NOLLI, R., BORGONOVO, A., OWEN, E. R., DUBERNARD, J. M., KAPILA, H., MARTIN, X., HAKIM, N., DAWAHRA, M.
(2001). Hand Transplantation: Ethics, Immunosuppression and Indications. J Hand Surg Eur Vol
26: 511-516
Kalantar-Zadeh, K., Kopple, J. D., Block, G., Humphreys, M. H.
(2001). Association Among SF36 Quality of Life Measures and Nutrition, Hospitalization, and Mortality in Hemodialysis. J. Am. Soc. Nephrol.
12: 2797-2806
[Abstract][Full Text]
Goldsmith, I. R.A., Lip, G. Y.H., Patel, R. L.
(2001). A prospective study of changes in the quality of life of patients following mitral valve repair and replacement. Eur. J. Cardiothorac. Surg.
20: 949-955
[Abstract][Full Text]
Peri, U. N., Fenves, A. Z., Middleton, J. P.
(2001). Improving survival of octogenarian patients selected for haemodialysis. Nephrol Dial Transplant
16: 2201-2206
[Abstract][Full Text]
Rebollo, P., Ortega, F., Baltar, J. M., Alvarez-Ude, F., Navascues, R. A., Alvarez-Grande, J.
(2001). Is the loss of health-related quality of life during renal replacement therapy lower in elderly patients than in younger patients?. Nephrol Dial Transplant
16: 1675-1680
[Abstract][Full Text]
Mittal, S. K., Ahern, L., Flaster, E., Maesaka, J. K., Fishbane, S.
(2001). Self-assessed physical and mental function of haemodialysis patients. Nephrol Dial Transplant
16: 1387-1394
[Abstract][Full Text]
Piillips, L., Davies, S. J., White, E.
(2001). Health-related quality of life assessment in end-stage renal failure. Journal of Research in Nursing
6: 658-670
[Abstract]
OJO, A. O., HANSON, J. A., MEIER-KRIESCHE, H.-U., OKECHUKWU, C. N., WOLFE, R. A., LEICHTMAN, A. B., AGODOA, L. Y., KAPLAN, B., PORT, F. K.
(2001). Survival in Recipients of Marginal Cadaveric Donor Kidneys Compared with Other Recipients and Wait-Listed Transplant Candidates. J. Am. Soc. Nephrol.
12: 589-597
[Abstract][Full Text]
Furth, S. L., Hwang, W., Yang, C., Neu, A. M., Fivush, B. A., Powe, N. R.
(2001). Relation Between Pediatric Experience and Treatment Recommendations for Children and Adolescents With Kidney Failure. JAMA
285: 1027-1033
[Abstract][Full Text]
Epstein, A. M., Ayanian, J. Z., Keogh, J. H., Noonan, S. J., Armistead, N., Cleary, P. D., Weissman, J. S., David-Kasdan, J. A., Carlson, D., Fuller, J., Marsh, D., Conti, R. M.
(2000). Racial Disparities in Access to Renal Transplantation -- Clinically Appropriate or Due to Underuse or Overuse?. NEJM
343: 1537-1544
[Abstract][Full Text]
Ledebo, I., Lameire, N., Charra, B., Locatelli, F., Kooistra, M., Kessler, M., Jacobs, C.
(2000). Improving the outcome of dialysis--opinion vs scientific evidence. Nephrol Dial Transplant
15: 1310-1316
[Full Text]
Morreim, E. H.
(2000). Quality of Life: Erosions and Opportunities Under Managed Care. J Law Med Ethics
28: 144-158
GARG, P. P., FURTH, S. L., FIVUSH, B. A., POWE, N. R.
(2000). Impact of Gender on Access to the Renal Transplant Waiting List for Pediatric and Adult Patients. J. Am. Soc. Nephrol.
11: 958-964
[Abstract][Full Text]
Wolfe, R. A., Ashby, V. B., Milford, E. L., Ojo, A. O., Ettenger, R. E., Agodoa, L. Y.C., Held, P. J., Port, F. K.
(1999). Comparison of Mortality in All Patients on Dialysis, Patients on Dialysis Awaiting Transplantation, and Recipients of a First Cadaveric Transplant. NEJM
341: 1725-1730
[Abstract][Full Text]
Mazzuchi, N., Gonzalez-Martinez, F., Carbonell, E., Curi, L., Fernandez-Cean, J., Orihuela, S.
(1999). Comparison of survival for haemodialysis patients vs renal transplant recipients treated in Uruguay. Nephrol Dial Transplant
14: 2849-2854
[Abstract][Full Text]
Garg, P. P., Frick, K. D., Diener-West, M., Powe, N. R.
(1999). Effect of the Ownership of Dialysis Facilities on Patients' Survival and Referral for Transplantation. NEJM
341: 1653-1660
[Abstract][Full Text]
Ayanian, J. Z., Cleary, P. D., Weissman, J. S., Epstein, A. M.
(1999). The Effect of Patients' Preferences on Racial Differences in Access to Renal Transplantation. NEJM
341: 1661-1669
[Abstract][Full Text]
Bass, E. B., Jenckes, M. W., Fink, N. E., Cagney, K. A., Wu, A. W., Sadler, J. H., Meyer, K. B., Levey, Andrews., Powe, N. R.
(1999). Use of Focus Groups to Identify Concerns about Dialysis. Med Decis Making
19: 287-295
[Abstract]
Rummans, T. A., Frost, M., Suman, V. J., Taylor, M., Novotny, P., Gendron, T., Johnson, R., Hartmann, L., Dose, A. M., Evans, R. W.
(1998). Quality of Life and Pain in Patients With Recurrent Breast and Gynecologic Cancer. Psychosomatics
39: 437-445
[Abstract][Full Text]
Plevak, D. J., De Ruyter, M. L.
(1998). Intensive Care of the Intra-Abdominal Organ Transplant Recipient. SEMIN CARDIOTHORAC VASC ANESTH
2: 155-165
[Abstract]
Gelijns, A. C., Richards, A. F., Williams, D. L., Oz, M. C., Oliveira, J., Moskowitz, A. J.
(1997). Evolving Costs of Long-Term Left Ventricular Assist Device Implantation. Ann. Thorac. Surg.
64: 1312-1319
[Abstract][Full Text]
WEINERT, C. R., GROSS, C. R., KANGAS, J. R., BURY, C. L., MARINELLI, W. A.
(1997). Health-related Quality of Life after Acute Lung Injury. Am. J. Respir. Crit. Care Med.
156: 1120-1128
[Abstract][Full Text]
Yufei Yuan, , Gafni, A., Russell, J. D., Ludwin, D.
(1994). Development of a Central Matching System for the Allocation of Cadaveric Kidneys: A simulation of Clinical Effectiveness versus Equity. Med Decis Making
14: 124-136
[Abstract]
Levinsky, N. G.
(1993). The Organization of Medical Care -- Lessons from the Medicare End Stage Renal Disease Program. NEJM
329: 1395-1399
[Full Text]
McCauley, C., Bremer, B. A.
(1991). Subjective Quality of Life Measures for Evaluating Medical Intervention. Eval Health Prof
14: 371-387
[Abstract]
Miller, R. J.
(1989). The role of chemotherapy in the hospice patient: A problem of definition. AM J HOSP PALLIAT CARE
6: 19-26
Simon, D. G.
(1986). A Cost-effectiveness Analysis of Cyclosporine in Cadaveric Kidney Transplantation. Med Decis Making
6: 199-207
[Abstract]
Cantani, A., Bamonte, G., Ceccoli, D., Biribicchi, G., Farinella, F.
(1986). Familial Juvenile Nephronophthisis: A Review and Differential Diagnosis. CLIN PEDIATR
25: 90-95
[Abstract]
Previous
