Pain is one of the most feared consequences of cancer. Control of pain from cancer should be possible with the approaches discussed above. Changing attitudes toward the effective use of narcotic analgesics, the development of novel routes and methods of administration, and a clinical approach based on scientific principles and humane care offer the promise of improved management of pain in patients with cancer.
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(2009). Classification of pain in cancer patients - a systematic literature review. Palliat Med
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[Abstract][Full Text]
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Pour, A. E., Parvizi, J., Sharkey, P. F., Hozack, W. J., Rothman, R. H.
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Benoliel, R., Epstein, J., Eliav, E., Jurevic, R., Elad, S.
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[Abstract][Full Text]
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(2007). Clinical Experience with Transdermal and Orally Administered Opioids in Palliative Care Patients--A Retrospective Study. Jpn J Clin Oncol
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[Abstract][Full Text]
Yun, Y. H., Park, S. M., Lee, K., Chang, Y. J., Heo, D. S., Kim, S.-Y., Hong, Y. S., Huh, B. Y.
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[Abstract][Full Text]
Reisfield, G. M., Silberstein, E. B., Wilson, G. R.
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[Abstract]
Stockler, M., Vardy, J., Pillai, A., Warr, D.
(2004). Acetaminophen (Paracetamol) Improves Pain and Well-Being in People With Advanced Cancer Already Receiving a Strong Opioid Regimen: A Randomized, Double-Blind, Placebo-Controlled Cross-Over Trial. JCO
22: 3389-3394
[Abstract][Full Text]
Dahl, J. L.
(2004). Pain: Impediments and Suggestions for Solutions. J Natl Cancer Inst Monogr
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[Abstract][Full Text]
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(2004). Methadone Versus Morphine As a First-Line Strong Opioid for Cancer Pain: A Randomized, Double-Blind Study. JCO
22: 185-192
[Abstract][Full Text]
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[Abstract][Full Text]
Gutgsell, T., Walsh, D., Zhukovsky, D. S., Gonzales, F., Lagman, R.
(2003). A prospective study of the pathophysiology and clinical characteristics of pain in a palliative medicine population. AM J HOSP PALLIAT CARE
20: 140-148
[Abstract]
Fizazi, K., Doubre, H., Le Chevalier, T., Riviere, A., Viala, J., Daniel, C., Robert, L., Barthelemy, P., Fandi, A., Ruffie, P.
(2003). Combination of Raltitrexed and Oxaliplatin Is an Active Regimen in Malignant Mesothelioma: Results of a Phase II Study. JCO
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[Abstract][Full Text]
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(2002). The Placorhen Study: A Double-Blind, Placebo-Controlled, Randomized Radionuclide Study with 186Re-Etidronate in Hormone-Resistant Prostate Cancer Patients with Painful Bone Metastases. JNM
43: 1150-1156
[Abstract][Full Text]
McNamara, P.
(2002). Opioid switching from morphine to transdermal fentanyl for toxicity reduction in palliative care. Palliat Med
16: 425-434
[Abstract]
Rozans, M., Dreisbach, A., Lertora, J. J.L., Kahn, M. J.
(2002). Palliative Uses of Methylphenidate in Patients With Cancer: A Review. JCO
20: 335-339
[Abstract][Full Text]
Kwarcinski, M., Pappagallo, M., Dickerson, E. D., Hulka, S., Knowlton, H. L.
(2001). Conversion ratio and cost of oxycodone.. AM J HOSP PALLIAT CARE
18: 159-160
Anderson, R., Saiers, J. H., Schlicht, C., Abram, S.
(2000). Continuous infusion sufentanil for malignant pain: A case report. AM J HOSP PALLIAT CARE
17: 265-268
O'Connor, A., Schug, S. A, Cardwell, H.
(2000). A comparison of the efficacy and safety of morphine and pethidine as analgesia for suspected renal colic in the emergency setting. Emerg. Med. J.
17: 261-264
[Abstract][Full Text]
Kumar, K S., Rajagopal, M R, Naseema, A M
(2000). Intravenous morphine for emergency treatment of cancer pain. Palliat Med
14: 183-188
[Abstract]
Duggleby, W.
(2000). Elderly hospice cancer patients' descriptions of their pain experiences. AM J HOSP PALLIAT CARE
17: 111-117
[Abstract]
Benjamin, L. J., Swinson, G. I., Nagel, R. L.
(2000). Sickle cell anemia day hospital: an approach for the management of uncomplicated painful crises. Blood
95: 1130-1136
[Abstract][Full Text]
Carver, A. C., Vickrey, B. G., Bernat, J. L., Keran, C., Ringel, S. P., Foley, K. M.
(1999). End-of-life care: A survey of US neurologists' attitudes, behavior, and knowledge. Neurology
53: 284-284
[Abstract][Full Text]
Nekolaichuk, C. L, Bruera, E., Spachynski, K., MacEachern, T., Hanson, J., Maguire, T. O
(1999). A comparison of patient and proxy symptom assessments in advanced cancer patients. Palliat Med
13: 311-323
[Abstract]
Sze, F. K.-h., Chung, T K, Wong, E., Lam, K K, Lo, R., Woo, J.
(1998). Pain in Chinese cancer patients under palliative care. Palliat Med
12: 271-277
[Abstract]
Oneschuk, D., Bruera, E.
(1998). Access to palliative medicine training for Canadian family medicine residents. Palliat Med
12: 23-27
[Abstract]
AARON, A. D.
(1997). Current Concepts Review - Treatment of Metastatic Adenocarcinoma of the Pelvis and the Extremities. JBJS
79: 917-32
[Full Text]
Yeo, W., Lam, K. K, Chan, A. T., Leung, T. W., Wu Nip, S. Y, Johnson, P. J
(1997). Transdermal fentanyl for severe cancer-related pain. Palliat Med
11: 233-239
[Abstract]
Shapiro, R. S.
(1996). Health Care Providers'Liability Exposure for Inappropriate Pain Management. J Law Med Ethics
24: 360-364
Jadad, A. R., Browman, G. P.
(1995). The WHO Analgesic Ladder for Cancer Pain Management: Stepping Up the Quality of Its Evaluation. JAMA
274: 1870-1873
[Abstract]
Ritch, P., Plezia, P., Rushing, D., Heilman, R., Finn, J., Andresen, S., Schobelock, M., Mosdell, K., Shepard, K.
(1995). A multicenter, multiple dose, open label study of the initiation of sustained-release morphine sulfate (SRMS) in chronic pain. AM J HOSP PALLIAT CARE
12: 18-23
Larue, F., Colleau, S. M, Brasseur, L., Cleeland, C. S
(1995). Multicentre study of cancer pain and its treatment in France. BMJ
310: 1034-1037
[Abstract][Full Text]
Saxena, A., Andley, M., Gnanasekaran, N.
(1994). Comparison of piroxicam and acetylsalicylic acid for pain in head and neck cancers: a double-blind study. Palliat Med
8: 223-229
[Abstract]
Cleeland, C. S., Gonin, R., Hatfield, A. K., Edmonson, J. H., Blum, R. H., Stewart, J. A., Pandya, K. J.
(1994). Pain and Its Treatment in Outpatients with Metastatic Cancer. NEJM
330: 592-596
[Abstract][Full Text]
Jacox, A., Carr, D. B., Payne, R.
(1994). New Clinical-Practice Guidelines for the Management of Pain in Patients with Cancer. NEJM
330: 651-655
[Full Text]
Morgan, A. E., Lindley, C. M., Berry, J. I.
(1994). Assessment of pain and patterns of analgesic use in hospice patients. AM J HOSP PALLIAT CARE
11: 13-25
[Abstract]
Von Roenn, J. H., Cleeland, C. S., Gonin, R., Hatfield, A. K., Pandya, K. J.
(1993). Physician Attitudes and Practice in Cancer Pain Management: A Survey From the Eastern Cooperative Oncology Group. ANN INTERN MED
119: 121-126
[Abstract][Full Text]
Berry, Z. S., Lynn, J.
(1993). Hospice Medicine. JAMA
270: 221-223
[Abstract]
Blackwell, N., Bangham, L., Hughes, M., Melzack, D., Trotman, I.
(1993). Subcutaneous ketorolac- a new development in pain control. Palliat Med
7: 63-65
[Abstract]
Portenoy, R.
(1992). Drug therapy for cancer pain.. AM J HOSP PALLIAT CARE
9: 22-31
Brookoff, D., Polomano, R.
(1992). Treating Sickle Cell Pain like Cancer Pain. ANN INTERN MED
116: 364-368
[Abstract]
Portenoy, R.
(1990). Drug therapy for cancer pain.. AM J HOSP PALLIAT CARE
7: 10-19
Blum, R. H., Simpson, P. K., Blum, D. S.
(1990). Factors limiting the use of indicated opioid analgesics for cancer pain. AM J HOSP PALLIAT CARE
7: 31-35
Rhymes, J.
(1990). Hospice Care in America. JAMA
264: 369-372
[Abstract]
Toscani, F., Barosi, K., Scazzina, M., Camerini, S.
(1989). Sodium naproxen: continuous subcutaneous infusion in neoplastic pain control. Palliat Med
3: 207-211
[Abstract]
Dunlop, R. J
(1989). Is terminal restlessness sometimes drug induced?. Palliat Med
3: 65-66
[Abstract]
Berry, J. I.
(1988). The use of analgesics: In patients with pain from terminal disease. AM J HOSP PALLIAT CARE
5: 26-42
Stern, T. A
(1988). Neuropsychiatric Effects of Narcotic Analgesia: Stern TA. Neuropsychiatric effects of narcotic analgesia. J In tensive Care Med 1988;3:237-238. J Intensive Care Med
3: 237-238
Enck, R. E.
(1988). Pain management: An overview. AM J HOSP PALLIAT CARE
5: 17-19
KERR, I. G., SONE, M., DeANGELIS, C., ISCOE, N., MacKENZIE, R., SCHUELLER, T.
(1988). Continuous Narcotic Infusion with Patient-Controlled Analgesia for Chronic Cancer Pain in Outpatients. ANN INTERN MED
108: 554-557
[Abstract]
Byrd, S., Taylor, K., Aitmiller, R.
(1987). Pain management practices in a home care hospice program: Physicians, staff should share responsibility. AM J HOSP PALLIAT CARE
4: 21-29
MULROW, C. D.
(1987). The Medical Review Article: State of the Science. ANN INTERN MED
106: 485-488
[Abstract]
Ench, R. E.
(1987). Alzheimer's Disease and Hospice Care. AM J HOSP PALLIAT CARE
4: 19-23