We assessed the relation of risk factors for cardiovascular disease to early atherosclerotic lesions in the aorta and coronary arteries in 35 persons (mean age at death, 18 years). Aortic involvement with fatty streaks was greater in blacks than in whites (37 vs. 17 percent, P less than 0.01). However, aortic fatty streaks were strongly related to antemortem levels of both total and low-density lipoprotein cholesterol (r = 0.67, P less than 0.0001 for each association), independently of race, sex, and age, and were inversely correlated with the ratio of high-density lipoprotein cholesterol to low-density plus very-low-density lipoprotein cholesterol (r = -0.35, P = 0.06). Coronary-artery fatty streaks were correlated with very-low-density lipoprotein cholesterol (r = 0.41, P = 0.04). Mean systolic blood-pressure levels also tended to be higher in the four subjects with coronary-artery fibrous plaques than in those without them: 112 mm Hg as compared with 104 (P = 0.09). These results document the importance of risk-factor levels to early anatomical changes in the aorta and coronary arteries. The progression of fatty streaks to fibrous plaques is uncertain, but these data suggest that a rational approach to the prevention of cardiovascular disease should begin early in life.
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[Abstract][Full Text]
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[Abstract]
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112: 3184-3209
[Abstract][Full Text]
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111: 1866-1868
[Full Text]
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[Abstract][Full Text]
Goodman, E., McEwen, B. S., Huang, B., Dolan, L. M., Adler, N. E.
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67: 9-15
[Abstract][Full Text]
Woodard, L. D., Kressin, N. R., Petersen, L. A.
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[Abstract][Full Text]
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[Abstract][Full Text]
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110: 2266-2275
[Full Text]
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158: 418-419
[Full Text]
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89: 108-113
[Abstract][Full Text]
von Birgelen, C., Hartmann, M., Mintz, G. S., Baumgart, D., Schmermund, A., Erbel, R.
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108: 2757-2762
[Abstract][Full Text]
Li, S., Chen, W., Srinivasan, S. R., Bond, M. G., Tang, R., Urbina, E. M., Berenson, G. S.
(2003). Childhood Cardiovascular Risk Factors and Carotid Vascular Changes in Adulthood: The Bogalusa Heart Study. JAMA
290: 2271-2276
[Abstract][Full Text]
Moran, C. M., Panzarino, V. M., Darden, P. M., Routt Reigart, J.
(2003). Preventive Services: Blood Pressure Checks at Well Child Visits. CLIN PEDIATR
42: 627-634
[Abstract]
American Diabetes Association,
(2003). Management of Dyslipidemia in Children and Adolescents With Diabetes. Diabetes Care
26: 2194-2197
[Full Text]
German, J. B., Roberts, M.-A., Watkins, S. M.
(2003). Genomics and Metabolomics as Markers for the Interaction of Diet and Health: Lessons from Lipids. J. Nutr.
133: 2078S-2083
[Abstract][Full Text]
Lee, T. C., O'Malley, P. G., Feuerstein, I., Taylor, A. J.
(2003). The prevalence and severity of coronaryartery calcification on coronary arterycomputed tomography in black and white subjects. J Am Coll Cardiol
41: 39-44
[Abstract][Full Text]
Treiber, F. A., Kamarck, T., Schneiderman, N., Sheffield, D., Kapuku, G., Taylor, T.
(2003). Cardiovascular Reactivity and Development of Preclinical and Clinical Disease States. Psychosom. Med.
65: 46-62
[Abstract][Full Text]
Srinivasan, S. R., Myers, L., Berenson, G. S.
(2002). Distribution and Correlates of Non-High-Density Lipoprotein Cholesterol in Children: The Bogalusa Heart Study. Pediatrics
110: e29-29
[Abstract][Full Text]
Deanfield, J.E.
(2002). The management of special patient populations. Eur Heart J Suppl
4: F19-F23
[Abstract]
Jaffer, F. A., O'Donnell, C. J., Larson, M. G., Chan, S. K., Kissinger, K. V., Kupka, M. J., Salton, C., Botnar, R. M., Levy, D., Manning, W. J.
(2002). Age and Sex Distribution of Subclinical Aortic Atherosclerosis: A Magnetic Resonance Imaging Examination of the Framingham Heart Study. Arterioscler. Thromb. Vasc. Bio.
22: 849-854
[Abstract][Full Text]
Miura, K., Nakagawa, H., Greenland, P.
(2002). Invited Commentary: Height-Cardiovascular Disease Relation: Where to Go from Here?. Am J Epidemiol
155: 688-689
[Full Text]
Perry, A. C., Okuyama, T., Tanaka, K., Signorile, J., Kaplan, T. A., Wang, X.
(2002). A Comparison of Health and Fitness-Related Variables in a Small Sample of Children of Japanese Descent on 2 Continents. Arch Pediatr Adolesc Med
156: 362-368
[Abstract][Full Text]
Bertram, C. E, Hanson, M. A
(2001). Animal models and programming of the metabolic syndrome: Type 2 diabetes. Br Med Bull
60: 103-121
[Abstract][Full Text]
Rogers, I. S., Emmett, P. M., the ALSPAC Study Team,
(2001). Fat Content of the Diet Among Preschool Children in Southwest Britain: II. Relationship With Growth, Blood Lipids, and Iron Status. Pediatrics
108: e49-49
[Abstract][Full Text]
Miura, K., Daviglus, M. L., Dyer, A. R., Liu, K., Garside, D. B., Stamler, J., Greenland, P.
(2001). Relationship of Blood Pressure to 25-Year Mortality Due to Coronary Heart Disease, Cardiovascular Diseases, and All Causes in Young Adult Men: The Chicago Heart Association Detection Project in Industry. Arch Intern Med
161: 1501-1508
[Abstract][Full Text]
Tuzcu, E. M., Kapadia, S. R., Tutar, E., Ziada, K. M., Hobbs, R. E., McCarthy, P. M., Young, J. B., Nissen, S. E.
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103: 2705-2710
[Abstract][Full Text]
Miyanishi, K., Yamamoto, T., Irisa, T., Yamashita, A., Jingushi, S., Noguchi, Y., Iwamoto, Y.
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40: 196-201
[Abstract][Full Text]
Stary, H. C
(2000). Lipid and macrophage accumulations in arteries of children and the development of atherosclerosis. Am. J. Clin. Nutr.
72
: 1297S-1306S
[Abstract][Full Text]
Simell, O., Niinikoski, H., Ronnemaa, T., Lapinleimu, H., Routi, T., Lagstrom, H., Salo, P., Jokinen, E., Viikari, J.
(2000). Special Turku Coronary Risk Factor Intervention Project for Babies (STRIP). Am. J. Clin. Nutr.
72
: 1316S-1331S
[Abstract][Full Text]
Rask-Nissila, L., Jokinen, E., Ronnemaa, T., Viikari, J., Tammi, A., Niinikoski, H., Seppanen, R., Tuominen, J., Simell, O.
(2000). Prospective, Randomized, Infancy-Onset Trial of the Effects of a Low-Saturated-Fat, Low-Cholesterol Diet on Serum Lipids and Lipoproteins Before School Age : The Special Turku Coronary Risk Factor Intervention Project (STRIP). Circulation
102: 1477-1483
[Abstract][Full Text]
Isasi, C. R., Shea, S., Deckelbaum, R. J., Couch, S. C., Starc, T. J., Otvos, J. D., Berglund, L.
(2000). Apolipoprotein epsilon 2 Allele Is Associated With an Anti-atherogenic Lipoprotein Profile in Children: The Columbia University BioMarkers Study. Pediatrics
106: 568-575
[Abstract][Full Text]
Rask-Nissila, L., Jokinen, E., Terho, P., Tammi, A., Lapinleimu, H., Ronnemaa, T., Viikari, J., Seppanen, R., Korhonen, T., Tuominen, J., Valimaki, I., Simell, O.
(2000). Neurological Development of 5-Year-Old Children Receiving a Low-Saturated Fat, Low-Cholesterol Diet Since Infancy: A Randomized Controlled Trial. JAMA
284: 993-1000
[Abstract][Full Text]
Treiber, F. A., Jackson, R. W., Davis, H., Pollock, J. S., Kapuku, G., Mensah, G. A., Pollock, D. M.
(2000). Racial Differences in Endothelin-1 at Rest and in Response to Acute Stress in Adolescent Males. Hypertension
35: 722-725
[Abstract][Full Text]
Alderson, T. S. J., Ogden, J.
(1999). What do mothers feed their children and why?. Health Educ Res
14: 717-727
[Abstract][Full Text]
Morrison, J. A., Jacobsen, D. W., Sprecher, D. L., Robinson, K., Khoury, P., Daniels, S. R.
(1999). Serum Glutathione in Adolescent Males Predicts Parental Coronary Heart Disease. Circulation
100: 2244-2247
[Abstract][Full Text]
Nader, P. R., Stone, E. J., Lytle, L. A., Perry, C. L., Osganian, S. K., Kelder, S., Webber, L. S., Elder, J. P., Montgomery, D., Feldman, H. A., Wu, M., Johnson, C., Parcel, G. S., Luepker, R. V.
(1999). Three-Year Maintenance of Improved Diet and Physical Activity: The CATCH Cohort. Arch Pediatr Adolesc Med
153: 695-704
[Abstract][Full Text]
Reynolds, K. D., Baranowski, T., Bishop, D. B., Farris, R. P., Binkley, D., Nicklas, T. A., Elmer, P. J.
(1999). Patterns in Child and Adolescent Consumption of Fruit and Vegetables: Effects of Gender and Ethnicity across Four Sites. J. Am. Coll. Nutr.
18: 248-254
[Abstract][Full Text]
Jolley, C. D., Dietschy, J. M., Turley, S. D.
(1999). Genetic differences in cholesterol absorption in 129/Sv and C57BL/6 mice: effect on cholesterol responsiveness. Am. J. Physiol. Gastrointest. Liver Physiol.
276: G1117-G1124
[Abstract][Full Text]
Toikka, J. O., Niemi, P., Ahotupa, M., Niinikoski, H., Viikari, J. S. A., Ronnemaa, T., Hartiala, J. J., Raitakari, O. T.
(1999). Large-Artery Elastic Properties in Young Men : Relationships to Serum Lipoproteins and Oxidized Low-Density Lipoproteins. Arterioscler. Thromb. Vasc. Bio.
19: 436-441
[Abstract][Full Text]
Gidding, S. S., Bookstein, L. C., Chomka, E. V.
(1998). Usefulness of Electron Beam Tomography in Adolescents and Young Adults With Heterozygous Familial Hypercholesterolemia. Circulation
98: 2580-2583
[Abstract][Full Text]
Kimm, S. Y. S., Payne, G. H., Stylianou, M. P., Waclawiw, M. A., Lichtenstein, C.
(1998). National Trends in the Management of Cardiovascular Disease Risk Factors in Children: Second NHLBI Survey of Primary Care Physicians. Pediatrics
102: 50e-50
[Abstract][Full Text]
McGill, H. C. Jr, McMahan, C. A., Tracy, R. E., Oalmann, M. C., Cornhill, J. F., Herderick, E. E., Strong, J. P.
(1998). Relation of a Postmortem Renal Index of Hypertension to Atherosclerosis and Coronary Artery Size in Young Men and Women. Arterioscler. Thromb. Vasc. Bio.
18: 1108-1118
[Abstract][Full Text]
Berenson, G. S., Srinivasan, S. R., Bao, W., Newman, W. P., Tracy, R. E., Wattigney, W. A., The Bogalusa Heart Study,
(1998). Association between Multiple Cardiovascular Risk Factors and Atherosclerosis in Children and Young Adults. NEJM
338: 1650-1656
[Abstract][Full Text]
Willi, S. M., Oexmann, M. J., Wright, N. M., Collop, N. A., Key Jr, L. L.
(1998). The Effects of a High-protein, Low-fat, Ketogenic Diet on Adolescents With Morbid Obesity: Body Composition, Blood Chemistries, and Sleep Abnormalities. Pediatrics
101: 61-67
[Abstract][Full Text]
Dwyer, T., Iwane, H., Dean, K., Odagiri, Y., Shimomitsu, T., Blizzard, L., Srinivasan, S., Nicklas, T., Wattigney, W., Riley, M., Berenson, G.
(1997). Differences in HDL Cholesterol Concentrations in Japanese, American, and Australian Children. Circulation
96: 2830-2836
[Abstract][Full Text]
Vuorio, A. F., Turtola, H., Kontula, K.
(1997). Neonatal Diagnosis of Familial Hypercholesterolemia in Newborns Born to a Parent With a Molecularly Defined Heterozygous Familial Hypercholesterolemia. Arterioscler. Thromb. Vasc. Bio.
17: 3332-3337
[Abstract][Full Text]
Niinikoski, H., Viikari, J., Ronnemaa, T., Helenius, H., Jokinen, E., Lapinleimu, H., Routi, T., Lagstrom, H., Seppanen, R., Valimaki, I., Simell, O.
(1997). Regulation of Growth of 7- to 36-Month-Old Children by Energy and Fat Intake in the Prospective, Randomized STRIP Baby Trial. Pediatrics
100: 810-816
[Abstract][Full Text]
Freedman, D. S., Serdula, M. K., Percy, C. A., Ballew, C., White, L.
(1997). Obesity, Levels of Lipids and Glucose, and Smoking among Navajo Adolescents. J. Nutr.
127: 2120-2120
[Abstract][Full Text]
Hayashi, K., Gohda, M., Matzno, S., Kubo, Y., Kido, H., Yamauchi, T., Nakamura, N.
(1997). Possible Mechanism of Action of AE0047, a Calcium Antagonist, on Triglyceride Metabolism. J. Pharmacol. Exp. Ther.
282: 882-890
[Abstract][Full Text]
Fitch, J., Garcia, R. E., Moodie, D. S., Secic, M.
(1997). Influence of Cholesterol Screening and Nutritional Counseling in Reducing Cholesterol Levels in Children. CLIN PEDIATR
36: 267-272
[Abstract]
Nader, P. R., Yang, M., Luepker, R. V., Parcel, G. S., Pirie, P., Feldman, H. A., Stone, E. J., Webber, L. S.
(1997). Parent and Physician Response to Children's Cholesterol Values of 200 mg/dL or Greater: The Child and Adolescent Trial for Cardiovascular Health Experiment. Pediatrics
99: e5-e5
[Abstract][Full Text]
Niinikoski, H., Lapinleimu, H., Viikari, J., Ronnemaa, T., Jokinen, E., Seppanen, R., Terho, P., Tuominen, J., Valimaki, I., Simell, O.
(1997). Growth Until 3 Years of Age in a Prospective, Randomized Trial of a Diet With Reduced Saturated Fat and Cholesterol. Pediatrics
99: 687-694
[Abstract][Full Text]
Daniels, S. R.
(1997). Consultation with the Specialist: The Diagnosis of Hypertension in Children: An Update. Pediatr. Rev.
18: 131-135
[Full Text]
Turner, S., Zimvrakaki, H., Athanasiou, K.
(1997). Investigating children's ideas about fat consumption and health: a comparative study. Health Education Journal
56: 329-339
[Abstract]
McGill, H. C. Jr, McMahan, C. A., Malcom, G. T., Oalmann, M. C., Strong, J. P.
(1997). Effects of Serum Lipoproteins and Smoking on Atherosclerosis in Young Men and Women. Arterioscler. Thromb. Vasc. Bio.
17: 95-106
[Abstract][Full Text]
Jousilahti, P., Vartiainen, E., Tuomilehto, J., Puska, P.
(1996). Twenty-Year Dynamics of Serum Cholesterol Levels in the Middle-Aged Population of Eastern Finland. ANN INTERN MED
125: 713-722
[Abstract][Full Text]
Niinikoski, H., Viikari, J., Ronnemaa, T., Lapinleimu, H., Jokinen, E., Salo, P., Seppanen, R., Leino, A., Tuominen, J., Valimaki, I., Simell, O.
(1996). Prospective Randomized Trial of Low-Saturated-Fat, Low-Cholesterol Diet During the First 3 Years of Life: The STRIP Baby Project. Circulation
94: 1386-1393
[Abstract][Full Text]
McGill, H. C. Jr, Strong, J. P., Tracy, R. E., McMahan, C. A., Oalmann, M. C.
(1995). Relation of a Postmortem Renal Index of Hypertension to Atherosclerosis in Youth. Arterioscler. Thromb. Vasc. Bio.
15: 2222-2228
[Abstract][Full Text]
Schieken, R. M.
(1995). Large Hearts in Children : Biology or Disease?. Circulation
92: 3156-3157
[Full Text]
Levine, G. N., Keaney, J. F., Vita, J. A.
(1995). Cholesterol Reduction in Cardiovascular Disease -- Clinical Benefits and Possible Mechanisms. NEJM
332: 512-521
[Full Text]
Uiterwaal, C. S. P. M., Grobbee, D. E., Witteman, J. C. M., van Stiphout, W.-A. H. J., Krauss, X. H., Havekes, L. M., de Bruijn, A. M., van Tol, A., Hofman, A.
(1994). Postprandial Triglyceride Response in Young Adult Men and Familial Risk for Coronary Atherosclerosis. ANN INTERN MED
121: 576-583
[Abstract][Full Text]
Klag, M. J., Ford, D. E., Mead, L. A., He, J., Whelton, P. K., Liang, K.-Y., Levine, D. M.
(1993). Serum Cholesterol in Young Men and Subsequent Cardiovascular Disease. NEJM
328: 313-318
[Abstract][Full Text]
Cale, L., Almond, L.
(1992). Physical activity levels of young children: a review of the evidence. Health Education Journal
51: 94-99
DeClue, T. J., Schocken, D. M.
(1991). Cholesterol Screening Management of Florida's Pediatric Population. CLIN PEDIATR
30: 340-342
[Abstract]
Stone, E. J., Perry, C. L., Luepker, R. V.
(1989). Synthesis of Cardiovascular Behavioral Research for Youth Health Promotion. Health Educ Behav
16: 155-169
Walter, H. J.
(1989). Primary Prevention of Chronic Disease among Children: The School-Based "Know Your Body" Intervention Trials. Health Educ Behav
16: 201-214
Butcher, A. H., Frank, G. C., Harsha, D. W., Serpas, D. C., Little, S. D., Nicklas, T. A., Hunter, S. MacD., Berenson, G. S.
(1988). Heart Smart: A School Health Program Meeting the 1990 Objectives for the Nation. Health Educ Behav
15: 17-34
[Abstract]
He, Q., Horlick, M., Fedun, B., Wang, J., Pierson, R. N. Jr, Heshka, S., Gallagher, D.
(2002). Trunk Fat and Blood Pressure in Children Through Puberty. Circulation
105: 1093-1098
[Abstract][Full Text]
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