The first 169 patients in whom percutaneous transluminal coronary angioplasty was performed have now been followed for five to eight years. The procedure was technically successful in 133 patients (79 percent). In the follow-up period, nine of the 133 patients died (five of cardiac disease), and actuarial cardiac survival was 96 percent at six years. All patients were symptomatic before angioplasty, but 67 percent of the 133 who had technically successful procedures were asymptomatic at the last follow-up evaluation. Exercise stress testing, positive in 97 percent before angioplasty, was positive at the last follow-up study in only 10 percent of the patients who had technically successful procedures. Stenosis recurred during the first six months in 30 percent of the patients, and six more recurrences were observed among the 41 patients who had follow-up angiograms at two to seven years. A second angioplasty was required in 27 patients, and coronary bypass surgery was subsequently needed in 19. Actuarial event-free survival (freedom from death, myocardial infarction, and coronary bypass surgery) was 79 percent at six years. Follow-up of patients with multivessel disease showed a higher mortality from cardiac causes and a lower rate of long-term success than occurred among patients with single-vessel disease. These long-term results indicate that most episodes of restenosis occurred within six months of angioplasty, but some late recurrences were seen. Patients with single-vessel disease had a better long-term outcome after angioplasty than those with multivessel disease.
This article has been cited by other articles:
Patel, M. R., Holmes, D. R. Jr
(2008). Next-Generation Drug-Eluting Stents: A Spirited Step Forward or More of the Same. JAMA
299: 1952-1953
[Full Text]
Salahas, A., Vrahatis, A., Karabinos, I., Antonellis, I., Ifantis, G., Gavaliatsis, I., Anthopoulos, P., Tavernarakis, A.
(2007). Success, Safety, and Efficacy of Implantation of Diamond-Like Carbon-Coated Stents. ANGIOLOGY
58: 203-210
[Abstract]
King, S. B. III
(2005). Angioplasty Is Better Than Medical Therapy for Alleviating Chronic Angina Pectoris. Arch Intern Med
165: 2589-2592
[Full Text]
Zellweger, M. J., Weinbacher, M., Zutter, A. W., Jeger, R. V., Mueller-Brand, J., Kaiser, C., Buser, P. T., Pfisterer, M. E.
(2003). Long-term outcome of patients with silent versus symptomatic ischemia six months after percutaneous coronary intervention and stenting. J Am Coll Cardiol
42: 33-40
[Abstract][Full Text]
Faxon, D.
(2002). Restenosis: do we need to understand it to treat it?. J Am Coll Cardiol
40: 2090-2091
[Full Text]
Serruys, P.W., Sianos, G., van der Giessen, W., Bonnier, H.J.R.M., Urban, P., Wijns, W., Benit, E., Vandormael, M., Dorr, R., Disco, C., Debbas, N., Silber, S.
(2002). Intracoronary {beta}-radiation to reduce restenosis after balloon angioplasty and stenting. The Beta Radiation In Europe (BRIE) study. Eur Heart J
23: 1351-1359
[Abstract][Full Text]
Agema, W. R. P., Jukema, J. W., Pimstone, S. N., Kastelein, J. J. P.
(2001). Genetic aspects of restenosis after percutaneous coronary interventions;towards more tailored therapy. Eur Heart J
22: 2058-2074
Rodriguez, A., Bernardi, V., Navia, J., Baldi, J., Grinfeld, L., Martinez, J., Vogel, D., Grinfeld, R., Delacasa, A., Garrido, M., Oliveri, R., Mele, E., Palacios, I., O'Neill, W., for the ERACI II Investigators,
(2001). Argentine randomized study: coronary angioplasty with stenting versus coronary bypass surgery in patients with multiple-vessel disease (ERACI II): 30-day and one-year follow-up results. J Am Coll Cardiol
37: 51-58
[Abstract][Full Text]
Miyatake, S.-I., Yukawa, H., Toda, H., Matsuoka, N., Takahashi, R., Hashimoto, N., Kontos, C. D.
(1999). Inhibition of Rat Vascular Smooth Muscle Cell Proliferation In Vitro and In Vivo by Recombinant Replication-Competent Herpes Simplex Virus • Editorial Comment. Stroke
30
: 2431-2439
[Abstract][Full Text]
Manegold, C., Alwazzeh, M., Jablonowski, H., Adams, O., Medve, M., Seidlitz, B., Heidland, U., Haussinger, D., Strauer, B.-E., Heintzen, M. P.
(1999). Prior Cytomegalovirus Infection and the Risk of Restenosis After Percutaneous Transluminal Coronary Balloon Angioplasty. Circulation
99: 1290-1294
[Abstract][Full Text]
Bech, G. J. W., Pijls, N. H. J., De Bruyne, B., Peels, K. H., Michels, H. R., Bonnier, H. J. R. M., Koolen, J. J.
(1999). Usefulness of Fractional Flow Reserve to Predict Clinical Outcome After Balloon Angioplasty. Circulation
99: 883-888
[Abstract][Full Text]
King, S. B., Williams, D. O., Chougule, P., Klein, J. L., Waksman, R., Hilstead, R., Macdonald, J., Anderberg, K., Crocker, I. R.
(1998). Endovascular ß-Radiation to Reduce Restenosis After Coronary Balloon Angioplasty : Results of the Beta Energy Restenosis Trial (BERT). Circulation
97: 2025-2030
[Abstract][Full Text]
Rohrer-Gubler, I., Niederhauser, U., Turina, M. I.
(1998). Late Outcome of Coronary Artery Bypass Grafting in Young Versus Older Patients. Ann. Thorac. Surg.
65: 377-382
[Abstract][Full Text]
Jenkins, G. M., Crow, M. T., Bilato, C., Gluzband, Y., Ryu, W.-S., Li, Z., Stetler-Stevenson, W., Nater, C., Froehlich, J. P., Lakatta, E. G., Cheng, L.
(1998). Increased Expression of Membrane-Type Matrix Metalloproteinase and Preferential Localization of Matrix Metalloproteinase-2 to the Neointima of Balloon-Injured Rat Carotid Arteries. Circulation
97: 82-90
[Abstract][Full Text]
Baker, W. F. JR
(1998). Thrombosis and Hemostasis in Cardiology: Review of Pathophysiology and Clinical Practice (Part I). CLIN APPL THROMB HEMOST
4: 51-75
[Abstract]
Aristides, M., Gliksman, M., Rajan, N., Davey, P.
(1998). Effectiveness and cost-effectiveness of single bolus treatment with abciximab (Reo Pro) in preventing restenosis following percutaneous transluminal coronary angioplasty in high risk patients. Heart
79: 12-17
[Abstract][Full Text]
Ormiston, J. A., Stewart, F. M., Roche, A. H. G., Webber, B. J., Whitlock, R. M. L., Webster, M. W. I.
(1997). Late Regression of the Dilated Site After Coronary Angioplasty : A 5-Year Quantitative Angiographic Study. Circulation
96: 468-474
[Abstract][Full Text]
Verin, V., Urban, P., Popowski, Y., Schwager, M., Nouet, P., Dorsaz, P. A., Chatelain, P., Kurtz, J. M., Rutishauser, W.
(1997). Feasibility of Intracoronary ß-Irradiation to Reduce Restenosis After Balloon Angioplasty: A Clinical Pilot Study. Circulation
95: 1138-1144
[Abstract][Full Text]
Zhao, X.-Q., Brown, B. G., Stewart, D. K., Hillger, L. A., Barnhart, H. X., Kosinski, A. S., Weintraub, W. S., King, S. B. III
(1996). Effectiveness of Revascularization in the Emory Angioplasty Versus Surgery Trial : A Randomized Comparison of Coronary Angioplasty With Bypass Surgery. Circulation
93: 1954-1962
[Abstract][Full Text]
Bennett, M. R., Schwartz, S. M.
(1995). Antisense Therapy for Angioplasty Restenosis : Some Critical Considerations. Circulation
92: 1981-1993
[Full Text]
Pomerantz, M.
(1995). Is there a renaissance in thoracic surgery?. J. Thorac. Cardiovasc. Surg.
109: 197-205
[Full Text]
Millaire, A., de Groote, P., Decoulx, E., Coullet, J.M., Marache, P., Brunet, J.Y., Bertrand, M.E., Ducloux, G.
(1994). Long-Term Follow-up After Peripheral and Coronary Angioplasty in Patients Undergoing Both Types of Procedure. ANGIOLOGY
45: 923-929
[Abstract]
King, S. B., Lembo, N. J., Weintraub, W. S., Kosinski, A. S., Barnhart, H. X., Kutner, M. H., Alazraki, N. P., Guyton, R. A., Zhao, X.-Q., The Emory Angioplasty versus Surgery Trial (EAST),
(1994). A Randomized Trial Comparing Coronary Angioplasty with Coronary Bypass Surgery. NEJM
331: 1044-1050
[Abstract][Full Text]
Fischman, D. L., Leon, M. B., Baim, D. S., Schatz, R. A., Savage, M. P., Penn, I., Detre, K., Veltri, L., Ricci, D., Nobuyoshi, M., Cleman, M., Heuser, R., Almond, D., Teirstein, P. S., Fish, R. D., Colombo, A., Brinker, J., Moses, J., Shaknovich, A., Hirshfeld, J., Bailey, S., Ellis, S., Rake, R., Goldberg, S., The Stent Restenosis Study Investigators,
(1994). A Randomized Comparison of Coronary-Stent Placement and Balloon Angioplasty in the Treatment of Coronary Artery Disease. NEJM
331: 496-501
[Abstract][Full Text]
The EPIC Investigators,
(1994). Use of a Monoclonal Antibody Directed against the Platelet Glycoprotein IIb/IIIa Receptor in High-Risk Coronary Angioplasty. NEJM
330: 956-961
[Abstract][Full Text]
Landau, C., Lange, R. A., Hillis, L. D.
(1994). Percutaneous Transluminal Coronary Angioplasty. NEJM
330: 981-993
[Full Text]
Yeager, R. A., Moneta, G. L.
(1989). Assessing Cardiac Risk in Vascular Surgical Patients: Current Status. PERSPECT VASC SURG ENDOVASC THER
2: 18-36
Previous
