In 220 consecutive outpatients with clinically suspected deep-vein thrombosis of the leg, we compared contrast venography with real-time B-mode ultrasonography, using the single criterion of vein compressibility with the ultrasound transducer probe. The common femoral and popliteal veins were evaluated for full compressibility (no thrombosis) and noncompressibility (thrombosis). Both veins were fully compressible in 142 of the 143 patients with normal venograms (specificity, 99 percent; 95 percent confidence interval, 97 to 100). All 66 patients with proximal-vein thrombosis had noncompressible femoral veins, popliteal veins, or both (sensitivity, 100 percent; 95 percent confidence interval, 95 to 100). For all patients (including 11 with calf-vein thrombi), sensitivity and specificity were 91 (95 percent confidence interval, 82 to 96) and 99 percent, respectively. The sensitivity for isolated calf-vein thrombosis was only 36 percent. The compression ultrasound test was repeated in a subset of 45 consecutive patients by a second examiner, unaware of the results of the first test, whose results agreed in all patients with those of the first examiner (kappa = 1). We conclude that ultrasonography with the single criterion of vein compressibility is a highly accurate, simple, objective, and reproducible noninvasive method for detecting proximal-vein thrombosis in outpatients with clinically suspected deep-venous thrombosis.
Source Information
Center for Thrombosis, Haemostasis and Atherosclerosis Research, Academic Medical Center, Amsterdam, the Netherlands.
This article has been cited by other articles:
Kalva, S. P., Jagannathan, J. P., Hahn, P. F., Wicky, S. T.
(2008). Venous Thromboembolism: Indirect CT Venography during CT Pulmonary Angiography--Should the Pelvis Be Imaged?. Radiology
246: 605-611
[Abstract][Full Text]
Remy-Jardin, M., Pistolesi, M., Goodman, L. R., Gefter, W. B., Gottschalk, A., Mayo, J. R., Sostman, H. D.
(2007). Management of Suspected Acute Pulmonary Embolism in the Era of CT Angiography: A Statement from the Fleischner Society. Radiology
245: 315-329
[Full Text]
Piazza, G., Seddighzadeh, A., Goldhaber, S. Z.
(2007). Double Trouble for 2,609 Hospitalized Medical Patients Who Developed Deep Vein Thrombosis: Prophylaxis Omitted More Often and Pulmonary Embolism More Frequent. Chest
132: 554-561
[Abstract][Full Text]
Uppal, B., Flinn, W. R., Benjamin, M. E.
(2007). The Bedside Insertion of Inferior Vena Cava Filters Using Ultrasound Guidance. PERSPECT VASC SURG ENDOVASC THER
19: 78-84
[Abstract]
Rutschmann, O. T, Cornuz, J., Poletti, P.-A., Bridevaux, P.-O., Hugli, O. W, Qanadli, S. D, Perrier, A.
(2007). Should pulmonary embolism be suspected in exacerbation of chronic obstructive pulmonary disease?. Thorax
62: 121-125
[Abstract][Full Text]
Dhupar, S., Iorio, R., Healy, W. L., Dhimitri, K.
(2006). A Comparison of Discharge and Two-Week Duplex Ultrasound Screening Protocols for Deep Venous Thrombosis Detection Following Primary Total Joint Arthroplasty. JBJS
88: 2380-2385
[Abstract][Full Text]
Grifoni, S., Vanni, S., Magazzini, S., Olivotto, I., Conti, A., Zanobetti, M., Polidori, G., Pieralli, F., Peiman, N., Becattini, C., Agnelli, G.
(2006). Association of persistent right ventricular dysfunction at hospital discharge after acute pulmonary embolism with recurrent thromboembolic events.. Arch Intern Med
166: 2151-2156
[Abstract][Full Text]
Ely, J. W., Osheroff, J. A., Chambliss, M. L., Ebell, M. H.
(2006). Approach to Leg Edema of Unclear Etiology. J Am Board Fam Med
19: 148-160
[Abstract][Full Text]
Subramaniam, R. M., Heath, R., Chou, T., Cox, K., Davis, G., Swarbrick, M.
(2005). Deep Venous Thrombosis: Withholding Anticoagulation Therapy after Negative Complete Lower Limb US Findings. Radiology
237: 348-352
[Abstract][Full Text]
Oudega, R., Hoes, A. W., Moons, K. G.M.
(2005). The Wells Rule Does Not Adequately Rule Out Deep Venous Thrombosis in Primary Care Patients. ANN INTERN MED
143: 100-107
[Abstract][Full Text]
Patel, S., Kazerooni, E. A.
(2005). Helical CT for the Evaluation of Acute Pulmonary Embolism. Am. J. Roentgenol.
185: 135-149
[Abstract][Full Text]
Perrier, A., Roy, P.-M., Sanchez, O., Le Gal, G., Meyer, G., Gourdier, A.-L., Furber, A., Revel, M.-P., Howarth, N., Davido, A., Bounameaux, H.
(2005). Multidetector-Row Computed Tomography in Suspected Pulmonary Embolism. NEJM
352: 1760-1768
[Abstract][Full Text]
Olin, J. W, Gustavson, S. M, Lookstein, R.
(2005). Images in vascular ultrasound: Do not overlook the subtle clues. Vasc Med
10: 63-64
Joffe, H. V., Kucher, N., Tapson, V. F., Goldhaber, S. Z., for the Deep Vein Thrombosis (DVT) FREE Steering C,
(2004). Upper-Extremity Deep Vein Thrombosis: A Prospective Registry of 592 Patients. Circulation
110: 1605-1611
[Abstract][Full Text]
Linkins, L.-A., Pasquale, P., Paterson, S., Kearon, C.
(2004). Change in Thrombus Length on Venous Ultrasound and Recurrent Deep Vein Thrombosis. Arch Intern Med
164: 1793-1796
[Abstract][Full Text]
Bates, S. M., Greer, I. A., Hirsh, J., Ginsberg, J. S.
(2004). Use of Antithrombotic Agents During Pregnancy: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest
126: 627S-644S
[Abstract][Full Text]
El Kheir, D., Buller, H.
(2004). One-Time Comprehensive Ultrasonography To Diagnose Deep Venous Thrombosis: Is That the Solution?. ANN INTERN MED
140: 1052-1053
[Full Text]
Rathbun, S. W., Whitsett, T. L., Vesely, S. K., Raskob, G. E.
(2004). Clinical Utility of D-dimer in Patients With Suspected Pulmonary Embolism and Nondiagnostic Lung Scans or Negative CT Findings. Chest
125: 851-855
[Abstract][Full Text]
Otten, H.-M. M. B., Mathijssen, J., ten Cate, H., Soesan, M., Inghels, M., Richel, D. J., Prins, M. H.
(2004). Symptomatic Venous Thromboembolism in Cancer Patients Treated With Chemotherapy: An Underestimated Phenomenon. Arch Intern Med
164: 190-194
[Abstract][Full Text]
Parma, M., Belotti, D., Marinoni, S., Pogliani, E. M.
(2003). Congenital Absence of the Inferior Vena Cava and Genetic Coagulation Abnormalities: A Rare Associated Risk Factor for Recurrent Idiopathic Deep Vein Thrombosis. CLIN APPL THROMB HEMOST
9: 347-348
[Abstract]
Schrecengost, J. E., LeGallo, R. D., Boyd, J. C., Moons, K. G.M., Gonias, S. L., Rose, C. E. Jr, Bruns, D. E.
(2003). Comparison of Diagnostic Accuracies in Outpatients and Hospitalized Patients of D-Dimer Testing for the Evaluation of Suspected Pulmonary Embolism. Clin. Chem.
49: 1483-1490
[Abstract][Full Text]
Stein, P. D., Hull, R. D., Patel, K. C., Olson, R. E., Ghali, W. A., Alshab, A. K., Meyers, F. A.
(2003). Venous Thromboembolic Disease: Comparison of the Diagnostic Process in Blacks and Whites. Arch Intern Med
163: 1843-1848
[Abstract][Full Text]
Quinlan, D. J., Alikhan, R., Gishen, P., Sidhu, P. S.
(2003). Variations in Lower Limb Venous Anatomy: Implications for US Diagnosis of Deep Vein Thrombosis. Radiology
228: 443-448
[Abstract][Full Text]
The Superficial Thrombophlebitis Treated by Enoxap,
(2003). A Pilot Randomized Double-blind Comparison of a Low-Molecular-Weight Heparin, a Nonsteroidal Anti-inflammatory Agent, and Placebo in the Treatment of Superficial Vein Thrombosis. Arch Intern Med
163: 1657-1663
[Abstract][Full Text]
Stein, P. D., Hull, R. D., Patel, K. C., Olson, R. E., Ghali, W. A., Alshab, A. K., Meyers, F. A.
(2003). Venous Thromboembolic Disease: Comparison of the Diagnostic Process in Men and Women. Arch Intern Med
163: 1689-1694
[Abstract][Full Text]
Lee, A. Y.Y., Levine, M. N., Baker, R. I., Bowden, C., Kakkar, A. K., Prins, M., Rickles, F. R., Julian, J. A., Haley, S., Kovacs, M. J., Gent, M., the Randomized Comparison of Low-Molecular-Weight,
(2003). Low-Molecular-Weight Heparin versus a Coumarin for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer. NEJM
349: 146-153
[Abstract][Full Text]
Stein, P. D., Hull, R. D., Ghali, W. A., Patel, K. C., Olson, R. E., Meyers, F. A., Kalra, N. K.
(2003). Tracking the Uptake of Evidence: Two Decades of Hospital Practice Trends for Diagnosing Deep Vein Thrombosis and Pulmonary Embolism. Arch Intern Med
163: 1213-1219
[Abstract][Full Text]
Bates, S. M., Kearon, C., Crowther, M., Linkins, L., O'Donnell, M., Douketis, J., Lee, A. Y.Y., Weitz, J. I., Johnston, M., Ginsberg, J. S.
(2003). A Diagnostic Strategy Involving a Quantitative Latex D-Dimer Assay Reliably Excludes Deep Venous Thrombosis. ANN INTERN MED
138: 787-794
[Abstract][Full Text]
Bates, S. M., Ginsberg, J. S.
(2002). How we manage venous thromboembolism during pregnancy. Blood
100: 3470-3478
[Abstract][Full Text]
Noren, A., Ottosson, E., Rosfors, S.
(2002). Is It Safe to Withhold Anticoagulation Based on a Single Negative Color Duplex Examination in Patients with Suspected Deep Venous Thrombosis? A Prospective 3-Month Follow-up Study. ANGIOLOGY
53: 521-527
[Abstract]
Maskell, N A, Cooke, S, Meecham Jones, D J, Prior, J G, Butland, R J A
(2002). The use of automated strain gauge plethysmography in the diagnosis of deep vein thrombosis. Br. J. Radiol.
75: 648-651
[Abstract][Full Text]
Baarslag, H.-J., van Beek, E. J.R., Koopman, M. M.W., Reekers, J. A.
(2002). Prospective Study of Color Duplex Ultrasonography Compared with Contrast Venography in Patients Suspected of Having Deep Venous Thrombosis of the Upper Extremities. ANN INTERN MED
136: 865-872
[Abstract][Full Text]
Pistolesi, M., Miniati, M.
(2002). Imaging techniques in treatment algorithms of pulmonary embolism. Eur Respir J
19: 28S-39s
[Abstract][Full Text]
Chunilal, S. D., Brill-Edwards, P. A., Stevens, P. B., Joval, J. P., McGinnis, J. A., Rupwate, M., Ginsberg, J. S.
(2002). The Sensitivity and Specificity of a Red Blood Cell Agglutination D-Dimer Assay for Venous Thromboembolism When Performed on Venous Blood. Arch Intern Med
162: 217-220
[Abstract][Full Text]
Perrier, A., Howarth, N., Didier, D., Loubeyre, P., Unger, P.-F., de Moerloose, P., Slosman, D., Junod, A., Bounameaux, H.
(2001). Performance of Helical Computed Tomography in Unselected Outpatients with Suspected Pulmonary Embolism. ANN INTERN MED
135: 88-97
[Abstract][Full Text]
Wells, P. S., Anderson, D. R., Rodger, M., Stiell, I., Dreyer, J. F., Barnes, D., Forgie, M., Kovacs, G., Ward, J., Kovacs, M. J.
(2001). Excluding Pulmonary Embolism at the Bedside without Diagnostic Imaging: Management of Patients with Suspected Pulmonary Embolism Presenting to the Emergency Department by Using a Simple Clinical Model and D-dimer. ANN INTERN MED
135: 98-107
[Abstract][Full Text]
Giess, C. S., Bach, A. M., Hann, L. E.
(2001). Lower Extremity Venous Sonography in the High-Risk Cancer Population: One Leg or Two?. Am. J. Roentgenol.
176: 1049-1052
[Abstract][Full Text]
Bates, S. M., Grand'Maison, A., Johnston, M., Naguit, I., Kovacs, M. J., Ginsberg, J. S.
(2001). A Latex D-Dimer Reliably Excludes Venous Thromboembolism. Arch Intern Med
161: 447-453
[Abstract][Full Text]
Ginsberg, J. S., Greer, I., Hirsh, J.
(2001). Use of Antithrombotic Agents During Pregnancy. Chest
119: 122S-131S
[Full Text]
HARTMANN, I. J. C., HAGEN, P. J., MELISSANT, C. F., POSTMUS, P. E., PRINS, M. H.
(2000). Diagnosing Acute Pulmonary Embolism . Effect of Chronic Obstructive Pulmonary Disease on the Performance of D-dimer Testing, Ventilation/Perfusion Scintigraphy, Spiral Computed Tomographic Angiography, and Conventional Angiography. Am. J. Respir. Crit. Care Med.
162: 2232-2237
[Abstract][Full Text]
Duwe, K. M., Shiau, M., Budorick, N. E., Austin, J. H. M., Berkmen, Y. M.
(2000). Evaluation of the Lower Extremity Veins in Patients with Suspected Pulmonary Embolism: A Retrospective Comparison of Helical CT Venography and Sonography. Am. J. Roentgenol.
175: 1525-1531
[Abstract][Full Text]
Brill-Edwards, P., Ginsberg, J. S., Gent, M., Hirsh, J., Burrows, R., Kearon, C., Geerts, W., Kovacs, M., Weitz, J. I., Robinson, K. S., Whittom, R., Couture, G., The Recurrence of Clot in This Pregnancy Study Gro,
(2000). Safety of Withholding Heparin in Pregnant Women with a History of Venous Thromboembolism. NEJM
343: 1439-1444
[Abstract][Full Text]
Maki, D. D., Kumar, N., Nguyen, B., Langer, J. E., Miller, W. T. Jr., Gefter, W. B.
(2000). Distribution of Thrombi in Acute Lower Extremity Deep Venous Thrombosis: Implications for Sonography and CT and MR Venography. Am. J. Roentgenol.
175: 1299-1301
[Abstract][Full Text]
(2000). Guidelines on diagnosis and management of acute pulmonary embolism. Eur Heart J
21: 1301-1336
Blum, J. E., Handmaker, H.
(2000). 1999 Plenary Session: Friday Imaging Symposium : Role of Small-Peptide Radiopharmaceuticals in the Evaluation of Deep Venous Thrombosis. RadioGraphics
20: 1187-1193
[Full Text]
Boccalon, H., Elias, A., Chale, J.-J., Cadene, A., Gabriel, S., for the Vascular Midi-Pyrenees Network Group,
(2000). Clinical Outcome and Cost of Hospital vs Home Treatment of Proximal Deep Vein Thrombosis With a Low-Molecular-Weight Heparin: The Vascular Midi-Pyrenees Study. Arch Intern Med
160: 1769-1773
[Abstract][Full Text]
Grifoni, S., Olivotto, I., Cecchini, P., Pieralli, F., Camaiti, A., Santoro, G., Conti, A., Agnelli, G., Berni, G.
(2000). Short-Term Clinical Outcome of Patients With Acute Pulmonary Embolism, Normal Blood Pressure, and Echocardiographic Right Ventricular Dysfunction. Circulation
101: 2817-2822
[Abstract][Full Text]
BERGHOUT, A., OUDKERK, M., HICKS, S.G., TENG, T.H., PILLAY, M., BULLER, H.R.
(2000). Active implementation of a consensus strategy improves diagnosis and management in suspected pulmonary embolism. QJM
93: 335-340
[Abstract][Full Text]
Perrier, A., Miron, M.-J., Desmarais, S., de Moerloose, P., Slosman, D., Didier, D., Unger, P.-F., Junod, A., Patenaude, J.-V., Bounameaux, H.
(2000). Using Clinical Evaluation and Lung Scan to Rule Out Suspected Pulmonary Embolism: Is It a Valid Option in Patients With Normal Results of Lower-Limb Venous Compression Ultrasonography?. Arch Intern Med
160: 512-516
[Abstract][Full Text]
Birdwell, B. G., Raskob, G. E., Whitsett, T. L., Durica, S. S., Comp, P. C., George, J. N., Tytle, T. L., Owen, W. L., McKee, P. A.
(2000). Predictive Value of Compression Ultrasonography for Deep Vein Thrombosis in Symptomatic Outpatients: Clinical Implications of the Site of Vein Noncompressibility. Arch Intern Med
160: 309-313
[Abstract][Full Text]
Hull, R. D., Raskob, G. E., Brant, R. F., Pineo, G. F., Elliott, G., Stein, P. D., Gottschalk, A., Valentine, K. A., Mah, A. F., for the American-Canadian Thrombosis Study Group,
(2000). Low-Molecular-Weight Heparin vs Heparin in the Treatment of Patients With Pulmonary Embolism. Arch Intern Med
160: 229-236
[Abstract][Full Text]
Le Blanche, A. F., Siguret, V., Settegrana, C., Bohus, S., Le Masne de Chermont, E., Andreux, J.-P., Gaussem, P.
(1999). Ruling Out Acute Deep Vein Thrombosis by ELISA Plasma D-Dimer Assay Versus Ultrasound in Inpatients More Than 70 Years Old. ANGIOLOGY
50: 873-882
[Abstract]
Tapson, V.
(1999). The Diagnostic Approach to Acute Venous Thromboembolism . Clinical Practice Guideline. Am. J. Respir. Crit. Care Med.
160: 1043-1066
[Full Text]
Michiels, J. J., Oortwijn, W. J., Naaborg, R.
(1999). Exclusion and Diagnosis of Deep Vein Thrombosis by a Rapid ELISA D-dimer Test, Compression Ultrasonography, and a Simple Clinical Model. CLIN APPL THROMB HEMOST
5: 171-180
[Abstract]
Yusen, R. D., Haraden, B. M., Gage, B. F., Woodward, R. S., Rubin, B. G., Botney, M. D.
(1999). Criteria for Outpatient Management of Proximal Lower Extremity Deep Venous Thrombosis. Chest
115: 972-979
[Abstract][Full Text]
Fraser, J. D., Anderson, D. R.
(1999). Deep Venous Thrombosis: Recent Advances and Optimal Investigation with US. Radiology
211: 9-24
[Full Text]
Anderson, D. R., Wells, P. S., Stiell, I., MacLeod, B., Simms, M., Gray, L., Robinson, K. S., Bormanis, J., Mitchell, M., Lewandowski, B., Flowerdew, G.
(1999). Thrombosis in the Emergency Department: Use of a Clinical Diagnosis Model to Safely Avoid the Need for Urgent Radiological Investigation. Arch Intern Med
159: 477-482
[Abstract][Full Text]
Bloemenkamp, K. W. M., Rosendaal, F. R., Buller, H. R., Helmerhorst, F. M., Colly, L. P., Vandenbroucke, J. P.
(1999). Risk of Venous Thrombosis With Use of Current Low-Dose Oral Contraceptives Is Not Explained by Diagnostic Suspicion and Referral Bias. Arch Intern Med
159: 65-70
[Abstract][Full Text]
Pasquariello, F., Kurol, M., Wiberg, S., Krekmanova, M., Leppert, J.
(1999). Diagnosis of Deep Venous Thrombosis of the Lower Limbs: It Is Premature to Introduce Ultrasound as a Routine Method. ANGIOLOGY
50: 31-36
[Abstract]
Bernardi, E., Prandoni, P., Lensing, A. W A, Agnelli, G., Guazzaloca, G., Scannapieco, G., Piovella, F., Verlato, F., Tomasi, C., Moia, M., Scarano, L., Girolami, A.
(1998). D-dimer testing as an adjunct to ultrasonography in patients with clinically suspected deep vein thrombosis: prospective cohort study. BMJ
317: 1037-1040
[Abstract][Full Text]
CICCONE, W. J., FOX, P. S., NEUMYER, M., RUBENS, D., PARRISH, W. M., PELLEGRINI, V. D.
(1998). Ultrasound Surveillance for Asymptomatic Deep Venous Thrombosis after Total Joint Replacement. JBJS
80: 1167-74
[Abstract][Full Text]
Goldhaber, S. Z.
(1998). Pulmonary Embolism. NEJM
339: 93-104
[Full Text]
Noel, A. A., Pappas, P. J., Haser, P. B., Silva, M. B. JR, Hobson, R. W.
(1998). Experience with Greenfield Filters in Pregnant Women for Deep Venous Thrombosis and Pulmonary Embolism Case Reports. VASC ENDOVASCULAR SURG
32: 367-372
[Abstract]
Anand, S. S., Wells, P. S., Hunt, D., Brill-Edwards, P., Cook, D., Ginsberg, J. S.
(1998). Does This Patient Have Deep Vein Thrombosis?. JAMA
279: 1094-1099
[Abstract][Full Text]
Davidson, B. L, Deppert, E. J
(1998). Ultrasound for the diagnosis of deep vein thrombosis: where to now?. BMJ
316: 2-3
[Full Text]
Cogo, A., Lensing, A. W A, Koopman, M. M W, Piovella, F., Siragusa, S., Wells, P. S, Villalta, S., Büller, H. R, Turpie, A. G G, Prandoni, P.
(1998). Compression ultrasonography for diagnostic management of patients with clinically suspected deep vein thrombosis: prospective cohort study. BMJ
316: 17-20
[Abstract][Full Text]
Girolami, A., Prandoni, P., Zanardi, A., Girolami, B., Zanon, E.
(1997). Isolated Iliac Vein Thrombosis During Oral Contraceptive Therapy in Three "Normal" Women. CLIN APPL THROMB HEMOST
3: 284-287
[Abstract]
Hull, R. D., Pineo, G. F.
(1997). Overview of Treatment of Venous Thromboembolism Based on Levels of Evidence. CLIN APPL THROMB HEMOST
3: S68-S71
Zahn, R., Fromm, E., Thoma, S., Lotter, R., Zander, M., Wagner, S., Seidl, K., Senges, J.
(1997). Local Venous Thrombosis After Cardiac Catheterization. ANGIOLOGY
48: 1-7
[Abstract]
GARINO, J. P., LOTKE, P. A., KITZIGER, K. J., STEINBERG, M. E.
(1996). Deep Venous Thrombosis after Total Joint Arthroplasty. The Role of Compression Ultrasonography and the Importance of the Experience of the Technician. JBJS
78: 1359-65
[Abstract][Full Text]
Harvey, R. L., Roth, E. J., Yarnold, P. R., Durham, J. R., Green, D.
(1996). Deep Vein Thrombosis in Stroke: The Use of Plasma D-Dimer Level as a Screening Test in the Rehabilitation Setting. Stroke
27: 1516-1520
[Abstract][Full Text]
Hirsh, J., Hoak, J.
(1996). Management of Deep Vein Thrombosis and Pulmonary Embolism : A Statement for Healthcare Professionals From the Council on Thrombosis (in Consultation With the Council on Cardiovascular Radiology), American Heart Association. Circulation
93: 2212-2245
[Full Text]
Levine, M., Gent, M., Hirsh, J., Leclerc, J., Anderson, D., Weitz, J., Ginsberg, J., Turpie, A. G., Demers, C., Kovacs, M., Geerts, W., Kassis, J., Desjardins, L., Cusson, J., Cruickshank, M., Powers, P., Brien, W., Haley, S., Willan, A.
(1996). A Comparison of Low-Molecular-Weight Heparin Administered Primarily at Home with Unfractionated Heparin Administered in the Hospital for Proximal Deep-Vein Thrombosis. NEJM
334: 677-681
[Abstract][Full Text]
Bona, R., Hickey, A., Greenwald, L., Sullivan, E., Livadiotis, P., Johnson, O., Kulak, A., Wajcs, S., Vose, K.
(1996). Low Risk of Subsequent Deep-Venous Thrombosis in Patients with a Negative Venous Duplex Scan. CLIN APPL THROMB HEMOST
2: 30-34
[Abstract]
Cogo, A., Lensing, A. W. A., Prandoni, P., Simioni, P., Bernardi, E., Girolami, B., Piccioli, A., Villalta, S., Wouter ten Cate, J., Girolami, A.
(1996). Relevance of Inherited Risk Factors in Young Patients with Deep-Vein Thrombosis. CLIN APPL THROMB HEMOST
2: 55-59
[Abstract]
Meyer, C., Berczeller, P. H., Needles, C. F., Green, D., Parise, P., Berrettini, M., Kettler, R. E., Greenberg, D. L., Root, R. K.
(1995). Clinical Problem-Solving: Decision Making by Analogy. NEJM
333: 127-129
[Full Text]
Hull, R. D., Raskob, G. E., Pineo, G. F., Brant, R. F.
(1995). The Treatment of Proximal Vein Thrombosis with Subcutaneous Low-Mole Molecular-Weight Heparin Compared with Continuous Intravenous Heparin. CLIN APPL THROMB HEMOST
1: 151-159
[Abstract]
Weinmann, E. E., Salzman, E. W.
(1994). Deep-Vein Thrombosis. NEJM
331: 1630-1641
[Full Text]
White, T. M., Kellis, D. S., Hightower, S. F.
(1994). Conformance of Clinical Practice to Established Recommendations for the Diagnosis and Treatment of Venous Thromboembolic Disease: Robin Revisited. American Journal of Medical Quality
9: 153-157
[Abstract]
Keefe, D. L., Roistacher, N., Pierri, M. K.
(1994). Evaluation of Suspected Deep Venous Thrombosis in Oncologic Patients. ANGIOLOGY
45: 771-775
[Abstract]
Cogo, A., Prandoni, P., Villalta, S., Polistena, P., Bernardi, E., Simioni, P., Vigo, M., Benedetti, L., Girolami, A.
(1994). Changing Features of Proximal Vein Thrombosis Over Time. ANGIOLOGY
45: 377-382
[Abstract]
Heijboer, H., Buller, H. R., Lensing, A., Turpie, A., Colly, L. P., ten Cate, J. W.
(1993). A Comparison of Real-Time Compression Ultrasonography with Impedance Plethysmography for the Diagnosis of Deep-Vein Thrombosis in Symptomatic Outpatients. NEJM
329: 1365-1369
[Abstract][Full Text]
Verstraete, M.
(1993). The Diagnosis and Treatment of Deep-Vein Thrombosis. NEJM
329: 1418-1420
[Full Text]
Elliott, C. G., Suchyta, M., Rose, S. C., Talbot, S., Ford, C., Raskob, G., Hull, R., Davidson, B.
(1993). Duplex Ultrasonography for the Detection of Deep Vein Thrombi After Total Hip or Knee Arthroplasty. ANGIOLOGY
44: 26-33
[Abstract]
Cogo, A., Lensing, A., Prandoni, P., Canova, G., De Toni, R., Cuppini, S., Ruol, A.
(1992). Failure of Thrombin-Antithrombin III Complexes in the Diagnosis of Deep Vein Thrombosis. ANGIOLOGY
43: 975-979
[Abstract]
Arkfeld, S. J., Rouse, G. A., de Lange, M.
(1991). Deep Venous Thrombosis of the Lower Extremity: Current Sonographic Concepts and Techniques. Journal of Diagnostic Medical Sonography
7: 2-6
[Abstract]
Smith, P. C.
(1990). Noninvasive venous investigation. Vasc Med
1: 139-166
Habscheid, W., Hohmann, M., Wilhelm, T., Epping, J.
(1990). Real-Time Ultrasound in the Diagnosis of Acute Deep Venous Thrombosis of the Lower Extremity. ANGIOLOGY
41: 599-608
[Abstract]
(1989). ULTRASOUND ACCURATELY DETECTS DEEP VENOUS THROMBOSIS. JWatch General
1989: 6-6
[Full Text]
Previous
