BACKGROUND. Pulmonary embolism is a potentially fatal disorder. Information about the outcome of clinically recognized pulmonary embolism is sparse, particularly given that new treatments for more seriously ill patients are now available. METHODS. We prospectively followed 399 patients with pulmonary embolism diagnosed by lung scanning and pulmonary angiography, who were enrolled in a multicenter diagnostic trial. We reviewed all hospitalizations, all new investigations of pulmonary embolism, and all deaths among the patients within one year of diagnosis. RESULTS. Of the 399 patients, 375 (94 percent) received treatment for pulmonary embolism, usually conventional anticoagulation. Only 10 patients (2.5 percent) died of pulmonary embolism; 9 of them had clinically suspected recurrent pulmonary embolism. Clinically apparent pulmonary embolism recurred in 33 patients (8.3 percent), of whom 45 percent died during follow-up. Ninety-five patients with pulmonary embolism (23.8 percent) died within one year. The conditions associated with these deaths were cancer (relative risk, 3.8; 95 percent confidence interval, 2.3 to 6.4), left-sided congestive heart failure (relative risk, 2.7; 95 percent confidence interval, 1.5 to 4.6), and chronic lung disease (relative risk, 2.2; 95 percent confidence interval, 1.2 to 4.0). The most frequent causes of death in patients with pulmonary embolism were cancer (in 34.7 percent), infection (22.1 percent), and cardiac disease (16.8 percent). CONCLUSIONS. When properly diagnosed and treated, clinically apparent pulmonary embolism was an uncommon cause of death, and it recurred in only a small minority of patients. Most deaths were due to underlying diseases. Patients with pulmonary embolism who had cancer, congestive heart failure, or chronic lung disease had a higher risk of dying within one year than did other patients with pulmonary embolism.
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Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903.
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[Abstract][Full Text]
Goodman, L. R.
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234: 654-658
[Full Text]
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Becattini, C., Agnelli, G., Prandoni, P., Silingardi, M., Salvi, R., Taliani, M. R., Poggio, R., Imberti, D., Ageno, W., Pogliani, E., Porro, F., Casazza, F.
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[Abstract][Full Text]
O'Neill, J, Murchison, J T, Wright, L, Williams, J
(2005). Effect of the introduction of helical CT on radiation dose in the investigation of pulmonary embolism. Br. J. Radiol.
78: 46-50
[Abstract][Full Text]
Prologo, J. D., Gilkeson, R. C., Diaz, M., Asaad, J.
(2004). CT Pulmonary Angiography: A Comparative Analysis of the Utilization Patterns in Emergency Department and Hospitalized Patients Between 1998 and 2003. Am. J. Roentgenol.
183: 1093-1096
[Abstract][Full Text]
Buller, H. R., Agnelli, G., Hull, R. D., Hyers, T. M., Prins, M. H., Raskob, G. E.
(2004). Antithrombotic Therapy for Venous Thromboembolic Disease: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest
126: 401S-428S
[Abstract][Full Text]
ten Wolde, M., Sohne, M., Quak, E., Mac Gillavry, M. R., Buller, H. R.
(2004). Prognostic Value of Echocardiographically Assessed Right Ventricular Dysfunction in Patients With Pulmonary Embolism. Arch Intern Med
164: 1685-1689
[Abstract][Full Text]
Pengo, V., Lensing, A. W.A., Prins, M. H., Marchiori, A., Davidson, B. L., Tiozzo, F., Albanese, P., Biasiolo, A., Pegoraro, C., Iliceto, S., Prandoni, P., the Thromboembolic Pulmonary Hypertension Study Gr,
(2004). Incidence of Chronic Thromboembolic Pulmonary Hypertension after Pulmonary Embolism. NEJM
350: 2257-2264
[Abstract][Full Text]
Rascona, D. A.
(2004). Prevention of Fatal Pulmonary Embolism in the Hospital. Chest
125: 1595-1596
[Full Text]
Kanne, J. P., Lalani, T. A.
(2004). Role of Computed Tomography and Magnetic Resonance Imaging for Deep Venous Thrombosis and Pulmonary Embolism. Circulation
109: I-15-I-21
[Abstract][Full Text]
Kavanagh, E. C., O'Hare, A., Hargaden, G., Murray, J. G.
(2004). Risk of Pulmonary Embolism After Negative MDCT Pulmonary Angiography Findings. Am. J. Roentgenol.
182: 499-504
[Abstract][Full Text]
Eichinger, S., Weltermann, A., Minar, E., Stain, M., Schonauer, V., Schneider, B., Kyrle, P. A.
(2004). Symptomatic Pulmonary Embolism and the Risk of Recurrent Venous Thromboembolism. Arch Intern Med
164: 92-96
[Abstract][Full Text]
Haydar, A. A, Goldsmith, D. J A
(2004). Pulmonary embolism-- or vasculitis?. JRSM
97: 27-28
[Full Text]
Hasegawa, I., Boiselle, P. M., Hatabu, H.
(2004). Bronchial Artery Dilatation on MDCT Scans of Patients with Acute Pulmonary Embolism: Comparison with Chronic or Recurrent Pulmonary Embolism. Am. J. Roentgenol.
182: 67-72
[Abstract][Full Text]
Fedullo, P. F., Tapson, V. F.
(2003). The Evaluation of Suspected Pulmonary Embolism. NEJM
349: 1247-1256
[Full Text]
Donato, A. A., Scheirer, J. J., Atwell, M. S., Gramp, J., Duszak, R. Jr
(2003). Clinical Outcomes in Patients With Suspected Acute Pulmonary Embolism and Negative Helical Computed Tomographic Results in Whom Anticoagulation Was Withheld. Arch Intern Med
163: 2033-2038
[Abstract][Full Text]
Iles, S., Dalen, J. E.
(2003). Clot Burden and Comorbidity in Natural History of Untreated Pulmonary Thromboembolism: Autopsy Data in the Trial by Barritt And Jordan. Chest
124: 1178-1179
[Full Text]
Heit, J. A.
(2003). The Potential Role of Direct Thrombin Inhibitors in the Prevention and Treatment of Venous Thromboembolism. Chest
124
: 40S-48S
[Abstract][Full Text]
Howard, R. S, Radcliffe, J., Hirsch, N. P
(2003). General medical care on the neuromedical intensive care unit. J. Neurol. Neurosurg. Psychiatry
74: iii10-15
[Full Text]
Meneveau, N., Ming, L. P., Seronde, M. F., Mersin, N., Schiele, F., Caulfield, F., Bernard, Y., Bassand, J.-P.
(2003). In-hospital and long-term outcome after sub-massive and massive pulmonary embolism submitted to thrombolytic therapy. Eur Heart J
24: 1447-1454
[Abstract][Full Text]
Horlander, K. T., Mannino, D. M., Leeper, K. V.
(2003). Pulmonary Embolism Mortality in the United States, 1979-1998: An Analysis Using Multiple-Cause Mortality Data. Arch Intern Med
163: 1711-1717
[Abstract][Full Text]
Agnelli, G., Prandoni, P., Becattini, C., Silingardi, M., Taliani, M. R., Miccio, M., Imberti, D., Poggio, R., Ageno, W., Pogliani, E., Porro, F., Zonzin, P., for the Warfarin Optimal Duration Italian Trial In,
(2003). Extended Oral Anticoagulant Therapy after a First Episode of Pulmonary Embolism. ANN INTERN MED
139: 19-25
[Abstract][Full Text]
Lee, A. Y.Y., Levine, M. N.
(2003). Venous Thromboembolism and Cancer: Risks and Outcomes. Circulation
107: I-17-21
[Abstract][Full Text]
Kearon, C.
(2003). Natural History of Venous Thromboembolism. Circulation
107: I-22-30
[Abstract][Full Text]
Patel, S., Kazerooni, E. A., Cascade, P. N.
(2003). Pulmonary Embolism: Optimization of Small Pulmonary Artery Visualization at Multi-Detector Row CT. Radiology
227: 455-460
[Abstract][Full Text]
ten Wolde, M., Tulevski, I.I., Mulder, J.W.M., Sohne, M., Boomsma, F., Mulder, B.J.M., Buller, H.R.
(2003). Brain Natriuretic Peptide as a Predictor of Adverse Outcome in Patients With Pulmonary Embolism. Circulation
107: 2082-2084
[Abstract][Full Text]
Bourriot, K., Couffinhal, T., Bernard, V., Montaudon, M., Bonnet, J., Laurent, F.
(2003). Clinical Outcome After a Negative Spiral CT Pulmonary Angiographic Finding in an Inpatient Population From Cardiology and Pneumology Wards. Chest
123: 359-365
[Abstract][Full Text]
Kearon, C.
(2003). Diagnosis of pulmonary embolism. CMAJ
168: 183-194
[Abstract][Full Text]
Madani, M. M., Jamieson, S. W.
(2003). Pulmonary Thromboendarterectomy. Card Surg Adult
2: 1205-1228
[Full Text]
Dalen, J. E.
(2002). The Uncertain Role of Thrombolytic Therapy in the Treatment of Pulmonary Embolism. Arch Intern Med
162: 2521-2523
[Full Text]
Pruszczyk, P., Szulc, M., Torbicki, A., Wood, K. E.
(2002). Cardiac Troponins in Acute Pulmonary Embolism. Chest
122: 2264-2265
[Full Text]
Prandoni, P., Lensing, A. W. A., Piccioli, A., Bernardi, E., Simioni, P., Girolami, B., Marchiori, A., Sabbion, P., Prins, M. H., Noventa, F., Girolami, A.
(2002). Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis. Blood
100: 3484-3488
[Abstract][Full Text]
Thabut, G., Thabut, D., Myers, R. P., Bernard-Chabert, B., Marrash-Chahla, R., Mal, H., Fournier, M.
(2002). Thrombolytic therapy of pulmonary embolism: A meta-analysis. J Am Coll Cardiol
40: 1660-1667
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Beckh, S., Bolcskei, P. L., Lessnau, K.-D.
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122: 1759-1773
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Dalen, J. E.
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122: 1801-1817
[Full Text]
Konstantinides, S., Geibel, A., Heusel, G., Heinrich, F., Kasper, W., the Management Strategies and Prognosis of Pulmona,
(2002). Heparin plus Alteplase Compared with Heparin Alone in Patients with Submassive Pulmonary Embolism. NEJM
347: 1143-1150
[Abstract][Full Text]
Col, N. F., Goldberg, R. J., Orr, R. K., Erban, J. K., Fortin, J. M., Chlebowski, R. T.
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22: 386-393
[Abstract]
Dalen, J. E.
(2002). Pulmonary Embolism: What Have We Learned Since Virchow?: Natural History, Pathophysiology, and Diagnosis. Chest
122: 1440-1456
[Full Text]
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(2002). Importance of Cardiac Troponins I and T in Risk Stratification of Patients With Acute Pulmonary Embolism. Circulation
106: 1263-1268
[Abstract][Full Text]
Podbregar, M., Krivec, B., Voga, G.
(2002). Impact of Morphologic Characteristics of Central Pulmonary Thromboemboli in Massive Pulmonary Embolism*. Chest
122: 973-979
[Abstract][Full Text]
Savin, M. A., Panicker, H. K., Sadiq, S., Albeer, Y. A., Olson, R. E.
(2002). Placement of Vena Cava Filters: Factors Affecting Technical Success and Immediate Complications. Am. J. Roentgenol.
179: 597-602
[Abstract][Full Text]
Grann, V. R., Jacobson, J. S., Thomason, D., Hershman, D., Heitjan, D. F., Neugut, A. I.
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[Abstract][Full Text]
Eckman, M. H., Singh, S. K., Erban, J. K., Kao, G.
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22: 108-124
[Abstract]
Cundiff, D. K.
(2002). Significant Omission in Antithrombotic Supplement. Chest
121: 1378-1379
[Full Text]
Rose, P. S., Punjabi, N. M., Pearse, D. B.
(2002). Treatment of Right Heart Thromboemboli. Chest
121: 806-814
[Abstract][Full Text]
Hershman, D., Sundararajan, V., Jacobson, J. S., Heitjan, D. F., Neugut, A. I., Grann, V. R.
(2002). Outcomes of Tamoxifen Chemoprevention for Breast Cancer in Very High-Risk Women: A Cost-Effectiveness Analysis. JCO
20: 9-16
[Abstract][Full Text]
LEE, J.-H., CHUN, Y.-G., LEE, I.-C., TUDER, R. M., HONG, S.-B., SHIM, T.-S., LIM, C.-M., KOH, Y., KIM, W.-S., KIM, D.-S., KIM, W.-D., LEE, S.-D.
(2001). Pathogenic Role of Endothelin 1 in Hemodynamic Dysfunction in Experimental Acute Pulmonary Thromboembolism. Am. J. Respir. Crit. Care Med.
164: 1282-1287
[Abstract][Full Text]
Tait, R C
(2001). Anticoagulation in patients with thromboembolic disease. Thorax
56: ii30-37
[Full Text]
Wells, P. S., Anderson, D. R., Rodger, M., Stiell, I., Dreyer, J. F., Barnes, D., Forgie, M., Kovacs, G., Ward, J., Kovacs, M. J.
(2001). Excluding Pulmonary Embolism at the Bedside without Diagnostic Imaging: Management of Patients with Suspected Pulmonary Embolism Presenting to the Emergency Department by Using a Simple Clinical Model and D-dimer. ANN INTERN MED
135: 98-107
[Abstract][Full Text]
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120: 115-119
[Abstract][Full Text]
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119: 1791-1800
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