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Previous Volume 327:1928-1937 December 31, 1992 Number 27 Next

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Abstract

There is an active inflammatory process in the airways of patients with asthma, even when the patients are asymptomatic. Some of the types of cells involved in this process possess the necessary biologic activities to produce many of the pathophysiologic features of asthma, but the underlying mechanisms have not yet been elucidated. Reducing the severity of the inflammatory process appears to be a reasonable goal of therapy, with potential long-range implications for the morbidity of asthma. Whether this theoretical benefit will be realized awaits further observation.

Source Information

Airway Disease Center, Case Western Reserve University School of Medicine, Cleveland, OH.

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