FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 331:1416-1420 November 24, 1994 Number 21 Next

	Full Text Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

ABSTRACT

Background Injections of radiocontrast agents are a frequent cause of acute decreases in renal function, occurring most often in patients with chronic renal insufficiency and diabetes mellitus.

Methods We prospectively studied 78 patients with chronic renal insufficiency (mean [±SD] serum creatinine concentration, 2.1 ±0.6 mg per deciliter [186 ±53 µmol per liter]) who underwent cardiac angiography. The patients were randomly assigned to receive 0.45 percent saline alone for 12 hours before and 12 hours after angiography, saline plus mannitol, or saline plus furosemide. The mannitol and furosemide were given just before angiography. Serum creatinine was measured before and for 48 hours after angiography, and urine was collected for 24 hours after angiography. An acute radiocontrast-induced decrease in renal function was defined as an increase in the base-line serum creatinine concentration of at least 0.5 mg per deciliter (44 µmol per liter) within 48 hours after the injection of radiocontrast agents.

Results Twenty of the 78 patients (26 percent) had an increase in the serum creatinine concentration of at least 0.5 mg per deciliter after angiography. Among the 28 patients in the saline group, 3 (11 percent) had such an increase in serum creatinine, as compared with 7 of 25 in the mannitol group (28 percent) and 10 of 25 in the furosemide group (40 percent) (P = 0.05). The mean increase in serum creatinine 48 hours after angiography was significantly greater in the furosemide group (P = 0.01) than in the saline group.

Conclusions In patients with chronic renal insufficiency who are undergoing cardiac angiography, hydration with 0.45 percent saline provides better protection against acute decreases in renal function induced by radiocontrast agents than does hydration with 0.45 percent saline plus mannitol or furosemide.

Source Information

From New England Deaconess Hospital, Joslin Diabetes Center, and Harvard Medical School -- all in Boston. Presented at the 25th Annual Meeting of the American Society of Nephrology, Baltimore, November 15-18, 1992.

Address reprint requests to Dr. Solomon at Joslin Diabetes Center, 1 Joslin Pl., Boston, MA 02215.

Full Text of this Article

Related Letters:

Prevention of Radiocontrast-Induced Renal Insufficiency
Shumate M. J., Pilote L., Eisenberg M. J., Solomon R., D'Elia J., Mann D.
Extract | Full Text  
N Engl J Med 1995; 332:1035-1036, Apr 13, 1995. Correspondence

This article has been cited by other articles:

• Weisbord, S. D., Mor, M. K., Resnick, A. L., Hartwig, K. C., Palevsky, P. M., Fine, M. J. (2008). Incidence and Outcomes of Contrast-Induced AKI Following Computed Tomography. CJASN 3: 1274-1281 [Abstract] [Full Text]  
• Maioli, M., Toso, A., Leoncini, M., Gallopin, M., Tedeschi, D., Micheletti, C., Bellandi, F. (2008). Sodium Bicarbonate Versus Saline for the Prevention of Contrast-Induced Nephropathy in Patients With Renal Dysfunction Undergoing Coronary Angiography or Intervention. J Am Coll Cardiol 52: 599-604 [Abstract] [Full Text]  
• Trivedi, H. (2008). Is There Enough Evidence to Support Use of N-Acetylcysteine in Contrast-Induced Nephropathy?. ANN INTERN MED 149: 213-213 [Full Text]  
• Kelly, A. M., Dwamena, B., Carlos, R. C. (2008). Is There Enough Evidence to Support Use of N-Acetylcysteine in Contrast-Induced Nephropathy?. ANN INTERN MED 149: 215-216 [Full Text]  
• Baumgarten, D. A., Ellis, J. H. (2008). Contrast-Induced Nephropathy: Contrast Material Not Required?. Am. J. Roentgenol. 191: 383-386 [Abstract] [Full Text]  
• Himmelfarb, J., Joannidis, M., Molitoris, B., Schietz, M., Okusa, M. D., Warnock, D., Laghi, F., Goldstein, S. L., Prielipp, R., Parikh, C. R., Pannu, N., Lobo, S. M., Shah, S., D'Intini, V., Kellum, J. A. (2008). Evaluation and Initial Management of Acute Kidney Injury. CJASN 3: 962-967 [Abstract] [Full Text]  
• Weisbord, S. D., Mor, M. K., Resnick, A. L., Hartwig, K. C., Sonel, A. F., Fine, M. J., Palevsky, P. M. (2008). Prevention, Incidence, and Outcomes of Contrast-Induced Acute Kidney Injury. Arch Intern Med 168: 1325-1332 [Abstract] [Full Text]  
• Kane, G. C., Stanson, A. W., Kalnicka, D., Rosenthal, D. W., Lee, C. U., Textor, S. C., Garovic, V. D. (2008). Comparison between gadolinium and iodine contrast for percutaneous intervention in atherosclerotic renal artery stenosis: clinical outcomes. Nephrol Dial Transplant 23: 1233-1240 [Abstract] [Full Text]  
• Mahesh, B., Yim, B., Robson, D., Pillai, R., Ratnatunga, C., Pigott, D. (2008). Does furosemide prevent renal dysfunction in high-risk cardiac surgical patients? Results of a double-blinded prospective randomised trial. Eur. J. Cardiothorac. Surg. 33: 370-376 [Abstract] [Full Text]  
• Ritz, E. (2008). Cardiovascular Literature--Beyond Nephrology. CJASN 3: 317-323 [Full Text]  
• Weisbord, S. D., Palevsky, P. M. (2008). Prevention of Contrast-Induced Nephropathy with Volume Expansion. CJASN 3: 273-280 [Abstract] [Full Text]  
• Heyman, S. N., Rosen, S., Rosenberger, C. (2008). Renal Parenchymal Hypoxia, Hypoxia Adaptation, and the Pathogenesis of Radiocontrast Nephropathy. CJASN 3: 288-296 [Abstract] [Full Text]  
• Del Duca, D., Iqbal, S., Rahme, E., Goldberg, P., de Varennes, B. (2007). Renal Failure After Cardiac Surgery: Timing of Cardiac Catheterization and Other Perioperative Risk Factors. Ann. Thorac. Surg. 84: 1264-1271 [Abstract] [Full Text]  
• Wong, G. T. C., Irwin, M. G. (2007). Contrast-induced nephropathy. Br J Anaesth 99: 474-483 [Abstract] [Full Text]  
• Lee, P.-T., Chou, K.-J., Liu, C.-P., Mar, G.-Y., Chen, C.-L., Hsu, C.-Y., Fang, H.-C., Chung, H.-M. (2007). Renal Protection for Coronary Angiography in Advanced Renal Failure Patients by Prophylactic Hemodialysis: A Randomized Controlled Trial. J Am Coll Cardiol 50: 1015-1020 [Abstract] [Full Text]  
• Poletti, P.-A., Saudan, P., Platon, A., Mermillod, B., Sautter, A.-M., Vermeulen, B., Sarasin, F. P., Becker, C. D., Martin, P.-Y. (2007). IV N-Acetylcysteine and Emergency CT: Use of Serum Creatinine and Cystatin C as Markers of Radiocontrast Nephrotoxicity. Am. J. Roentgenol. 189: 687-692 [Abstract] [Full Text]  
• Venkataraman, R., Kellum, J. A. (2007). Defining Acute Renal Failure: The RIFLE Criteria. J Intensive Care Med 22: 187-193 [Abstract]  
• Solomon, R. (2007). Contrast media nephropathy--how to diagnose and how to prevent?. Nephrol Dial Transplant 22: 1812-1815 [Full Text]  
• Authors/Task Force Members, , Bassand, J.-P., Hamm, C. W., Ardissino, D., Boersma, E., Budaj, A., Fernandez-Aviles, F., Fox, K. A.A., Hasdai, D., Ohman, E. M., Wallentin, L., Wijns, W., ESC Committee for Practice Guidelines (CPG), , Vahanian, A., Camm, J., De Caterina, R., Dean, V., Dickstein, K., Filippatos, G., Kristensen, S. D., Widimsky, P., McGregor, K., Sechtem, U., Tendera, M., Hellemans, I., Gomez, J. L. Z., Silber, S., Funck-Brentano, C., Document Reviewers, , Kristensen, S. D., Andreotti, F., Benzer, W., Bertrand, M., Betriu, A., De Caterina, R., DeSutter, J., Falk, V., Ortiz, A. F., Gitt, A., Hasin, Y., Huber, K., Kornowski, R., Lopez-Sendon, J., Morais, J., Nordrehaug, J. E., Silber, S., Steg, P. G., Thygesen, K., Tubaro, M., Turpie, A. G.G., Verheugt, F., Windecker, S. (2007). Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes: The Task Force for the Diagnosis and Treatment of Non-ST-Segment Elevation Acute Coronary Syndromes of the European Society of Cardiology. Eur Heart J 28: 1598-1660 [Full Text]  
• Onbasili, A. O, Yeniceriglu, Y., Agaoglu, P., Karul, A., Tekten, T., Akar, H., Discigil, G. (2007). Trimetazidine in the prevention of contrast-induced nephropathy after coronary procedures. Heart 93: 698-702 [Abstract] [Full Text]  
• Briguori, C., Airoldi, F., D'Andrea, D., Bonizzoni, E., Morici, N., Focaccio, A., Michev, I., Montorfano, M., Carlino, M., Cosgrave, J., Ricciardelli, B., Colombo, A. (2007). Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): A Randomized Comparison of 3 Preventive Strategies. Circulation 115: 1211-1217 [Abstract] [Full Text]  
• Venkataraman, R., Kellum, J. A. (2007). Prevention of Acute Renal Failure. Chest 131: 300-308 [Abstract] [Full Text]  
• Mannebach, P. C., Dieter, R. S., Marks, D. S. (2006). Use of Gadolinium-Based Angiography for Renal Artery Stenting in a Patient With Renal Insufficiency: A Case Report. ANGIOLOGY 57: 526-529 [Abstract]  
• Dussol, B., Morange, S., Loundoun, A., Auquier, P., Berland, Y. (2006). A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients. Nephrol Dial Transplant 21: 2120-2126 [Abstract] [Full Text]  
• Becker, J., Thompson, H., Remy-Jardin, M., Remy, J., Dequiedt, P. (2006). Renal Safety of Gadolinium-based Contrast Agent for Ionizing Radiation Imaging.. Radiology 240: 301-302 [Full Text]  
• Pannu, N., Wiebe, N., Tonelli, M., for the Alberta Kidney Disease Network, (2006). Prophylaxis Strategies for Contrast-Induced Nephropathy. JAMA 295: 2765-2779 [Abstract] [Full Text]  
• Prasad, P. V. (2006). Functional MRI of the kidney: tools for translational studies of pathophysiology of renal disease. Am. J. Physiol. Renal Physiol. 290: F958-F974 [Abstract] [Full Text]  
• Tepel, M., Aspelin, P., Lameire, N. (2006). Contrast-Induced Nephropathy: A Clinical and Evidence-Based Approach. Circulation 113: 1799-1806 [Full Text]  
• Williams, M. E. (2006). Coronary Revascularization in Diabetic Chronic Kidney Disease/End-Stage Renal Disease: A Nephrologist's Perspective. CJASN 1: 209-220 [Full Text]  
• Remy-Jardin, M., Bahepar, J., Lafitte, J.-J., Dequiedt, P., Ertzbischoff, O., Bruzzi, J., Delannoy-Deken, V., Duhamel, A., Remy, J. (2006). Multi-Detector Row CT Angiography of Pulmonary Circulation with Gadolinium-based Contrast Agents: Prospective Evaluation in 60 Patients. Radiology 238: 1022-1035 [Abstract] [Full Text]  
• Barrett, B. J., Parfrey, P. S. (2006). Preventing Nephropathy Induced by Contrast Medium. NEJM 354: 379-386 [Full Text]  
• Gill, N., Nally, J. V. Jr, Fatica, R. A. (2005). Renal Failure Secondary to Acute Tubular Necrosis: Epidemiology, Diagnosis, and Management. Chest 128: 2847-2863 [Abstract] [Full Text]  
• Brinker, J. A., Davidson, C. J., Laskey, W. (2005). Preventing in-hospital cardiac and renal complications in high-risk PCI patients. Eur Heart J Suppl 7: G13-G24 [Abstract] [Full Text]  
• Sear, J. W. (2005). Kidney dysfunction in the postoperative period. Br J Anaesth 95: 20-32 [Abstract] [Full Text]  
• Gomes, V O, Poli de Figueredo, C E, Caramori, P, Lasevitch, R, Bodanese, L C, Araujo, A, Roedel, A P, Caramori, A P, Brito, F S Jr, Bezerra, H G, Nery, P, Brizolara, A (2005). N-acetylcysteine does not prevent contrast induced nephropathy after cardiac catheterisation with an ionic low osmolality contrast medium: a multicentre clinical trial. Heart 91: 774-778 [Abstract] [Full Text]  
• Katzberg, R. W. (2005). Contrast Medium-induced Nephrotoxicity: Which Pathway?. Radiology 235: 752-755 [Full Text]  
• Goldenberg, I., Matetzky, S. (2005). Nephropathy induced by contrast media: pathogenesis, risk factors and preventive strategies. CMAJ 172: 1461-1471 [Abstract] [Full Text]  
• Weisbord, S. D., Palevsky, P. M. (2005). Radiocontrast-Induced Acute Renal Failure. J Intensive Care Med 20: 63-75 [Abstract]  
• Kwolek, C. J. (2004). Endovascular Management of Renal Artery Stenosis: Current Techniques and Results. PERSPECT VASC SURG ENDOVASC THER 16: 261-276 [Abstract]  
• Gleeson, T. G., Bulugahapitiya, S. (2004). Contrast-Induced Nephropathy. Am. J. Roentgenol. 183: 1673-1689 [Full Text]  
• Maeder, M., Klein, M., Fehr, T., Rickli, H. (2004). Contrast nephropathy: Review focusing on prevention. J Am Coll Cardiol 44: 1763-1771 [Abstract] [Full Text]  
• Spargias, K., Alexopoulos, E., Kyrzopoulos, S., Iacovis, P., Greenwood, D. C., Manginas, A., Voudris, V., Pavlides, G., Buller, C. E., Kremastinos, D., Cokkinos, D. V. (2004). Ascorbic Acid Prevents Contrast-Mediated Nephropathy in Patients With Renal Dysfunction Undergoing Coronary Angiography or Intervention. Circulation 110: 2837-2842 [Abstract] [Full Text]  
• Ix, J. H., McCulloch, C. E., Chertow, G. M. (2004). Theophylline for the prevention of radiocontrast nephropathy: a meta-analysis. Nephrol Dial Transplant 19: 2747-2753 [Abstract] [Full Text]  
• Gupta, R., Birnbaum, Y., Uretsky, B. F. (2004). The renal patient with coronary artery disease: Current concepts and dilemmas. J Am Coll Cardiol 44: 1343-1353 [Abstract] [Full Text]  
• Bettmann, M. A. (2004). Frequently Asked Questions: Iodinated Contrast Agents. RadioGraphics 24: S3-S10 [Abstract] [Full Text]  
• Briguori, C., Colombo, A., Airoldi, F., Violante, A., Castelli, A., Balestrieri, P., Paolo Elia, P., Golia, B., Lepore, S., Riviezzo, G., Scarpato, P., Librera, M., Focaccio, A., Ricciardelli, B. (2004). N-acetylcysteine versus fenoldopam mesylate to prevent contrast agent-associated nephrotoxicity. J Am Coll Cardiol 44: 762-765 [Abstract] [Full Text]  
• Lassnigg, A., Schmidlin, D., Mouhieddine, M., Bachmann, L. M., Druml, W., Bauer, P., Hiesmayr, M. (2004). Minimal Changes of Serum Creatinine Predict Prognosis in Patients after Cardiothoracic Surgery: A Prospective Cohort Study. J. Am. Soc. Nephrol. 15: 1597-1605 [Abstract] [Full Text]  
• Merten, G. J., Burgess, W. P., Gray, L. V., Holleman, J. H., Roush, T. S., Kowalchuk, G. J., Bersin, R. M., Van Moore, A., Simonton, C. A. III, Rittase, R. A., Norton, H. J., Kennedy, T. P. (2004). Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate: A Randomized Controlled Trial. JAMA 291: 2328-2334 [Abstract] [Full Text]  
• Chertow, G. M. (2004). Prevention of Radiocontrast Nephropathy: Back to Basics. JAMA 291: 2376-2377 [Full Text]  
• Cox, C. D., Tsikouris, J. P. (2004). Preventing Contrast Nephropathy: What Is the Best Strategy? A Review of the Literature. J Clin Pharmacol 44: 327-337 [Abstract] [Full Text]  
• Ayerdi, J., Hodgson, K. J. (2004). Balloon Angioplasty and Stenting for Renovascular Occlusive Disease. PERSPECT VASC SURG ENDOVASC THER 16: 25-38 [Abstract]  
• Kshirsagar, A. V., Poole, C., Mottl, A., Shoham, D., Franceschini, N., Tudor, G., Agrawal, M., Denu-Ciocca, C., Magnus Ohman, E., Finn, W. F. (2004). N-Acetylcysteine for the Prevention of Radiocontrast Induced Nephropathy: A Meta-Analysis of Prospective Controlled Trials. J. Am. Soc. Nephrol. 15: 761-769 [Abstract] [Full Text]  
• Briguori, C., Colombo, A., Violante, A., Balestrieri, P., Manganelli, F., Paolo Elia, P., Golia, B., Lepore, S., Riviezzo, G., Scarpato, P., Focaccio, A., Librera, M., Bonizzoni, E., Ricciardelli, B. (2004). Standard vs double dose of N-acetylcysteine to prevent contrast agent associated nephrotoxicity. Eur Heart J 25: 206-211 [Abstract] [Full Text]  
• Goldenberg, I., Shechter, M., Matetzky, S., Jonas, M., Adam, M., Pres, H., Elian, D., Agranat, O., Schwammenthal, E., Guetta, V. (2004). Oral acetylcysteine as an adjunct to saline hydration for the prevention of contrast-induced nephropathy following coronary angiography: A randomized controlled trial and review of the current literature. Eur Heart J 25: 212-218 [Abstract] [Full Text]  
• Fishbane, S., Durham, J. H., Marzo, K., Rudnick, M. (2004). N-Acetylcysteine In The Prevention Of Radiocontrast-Induced Nephropathy. J. Am. Soc. Nephrol. 15: 251-260 [Abstract] [Full Text]  
• Hoffmann, U., Fischereder, M., Kruger, B., Drobnik, W., Kramer, B. K. (2004). The Value of N-Acetylcysteine in the Prevention of Radiocontrast Agent-Induced Nephropathy Seems Questionable. J. Am. Soc. Nephrol. 15: 407-410 [Abstract] [Full Text]  
• Baker, C. S. R., Johnston, A., Baker, L. R. I., Knight, C. J. (2003). Reply. J Am Coll Cardiol 42: 2169-2170 [Full Text]  
• Baker, C. S. R., Johnston, A., Baker, L. R. I., Knight, C. J. (2003). Did contrast nephropathy in rappid really occur? reply. J Am Coll Cardiol 42: 2167-2169 [Full Text]  
• Sadeghi, H. M., Stone, G. W., Grines, C. L., Mehran, R., Dixon, S. R., Lansky, A. J., Fahy, M., Cox, D. A., Garcia, E., Tcheng, J. E., Griffin, J. J., Stuckey, T. D., Turco, M., Carroll, J. D. (2003). Impact of Renal Insufficiency in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction. Circulation 108: 2769-2775 [Abstract] [Full Text]  
• Thomsen, H. S. (2003). Guidelines for Contrast Media from the European Society of Urogenital Radiology. Am. J. Roentgenol. 181: 1463-1471 [Full Text]  
• Stone, G. W., McCullough, P. A., Tumlin, J. A., Lepor, N. E., Madyoon, H., Murray, P., Wang, A., Chu, A. A., Schaer, G. L., Stevens, M., Wilensky, R. L., O'Neill, W. W. (2003). Fenoldopam Mesylate for the Prevention of Contrast-Induced Nephropathy: A Randomized Controlled Trial. JAMA 290: 2284-2291 [Abstract] [Full Text]  
• Marenzi, G., Marana, I., Lauri, G., Assanelli, E., Grazi, M., Campodonico, J., Trabattoni, D., Fabbiocchi, F., Montorsi, P., Bartorelli, A. L. (2003). The Prevention of Radiocontrast-Agent-Induced Nephropathy by Hemofiltration. NEJM 349: 1333-1340 [Abstract] [Full Text]  
• Thomsen, H S, Morcos, S K (2003). Contrast media and the kidney: European Society of Urogenital Radiology (ESUR) Guidelines. Br. J. Radiol. 76: 513-518 [Abstract] [Full Text]  
• Mehta, R. L., Chertow, G. M. (2003). Acute Renal Failure Definitions and Classification: Time for Change?. J. Am. Soc. Nephrol. 14: 2178-2187 [Full Text]  
• Levine, G. N., Kern, M. J., Berger, P. B., Brown, D. L., Klein, L. W., Kereiakes, D. J., Sanborn, T. A., Jacobs, A. K., for the American Heart Association Diagnostic and, (2003). Management of Patients Undergoing Percutaneous Coronary Revascularization. ANN INTERN MED 139: 123-136 [Abstract] [Full Text]  
• Baker, C. S. R., Wragg, A., Kumar, S., De Palma, R., Baker, L. R. I., Knight, C. J. (2003). A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study. J Am Coll Cardiol 41: 2114-2118 [Abstract] [Full Text]  
• Gruber, S. J., Shapiro, C. J., Braun, C., Birck, R., Bridges, C. M., Swaroop, V. S., Cuddihy, M.-T., Aspelin, P., Berg, K. J. (2003). Nephropathy Induced by Contrast Medium. NEJM 348: 2257-2259 [Full Text]  
• Provenchere, S., Plantefeve, G., Hufnagel, G., Vicaut, E., de Vaumas, C., Lecharny, J.-B., Depoix, J.-P., Vrtovsnik, F., Desmonts, J.-M., Philip, I. (2003). Renal Dysfunction After Cardiac Surgery with Normothermic Cardiopulmonary Bypass: Incidence, Risk Factors, and Effect on Clinical Outcome. Anesth. Analg. 96: 1258-1264 [Abstract] [Full Text]  
• Wijeysundera, D. N., Rao, V., Beattie, W. S., Ivanov, J., Karkouti, K. (2003). Evaluating Surrogate Measures of Renal Dysfunction After Cardiac Surgery. Anesth. Analg. 96: 1265-1273 [Abstract] [Full Text]  
• De Vriese, A. S. (2003). Prevention and Treatment of Acute Renal Failure in Sepsis. J. Am. Soc. Nephrol. 14: 792-805 [Full Text]  
• Singri, N., Ahya, S. N., Levin, M. L. (2003). Acute Renal Failure. JAMA 289: 747-751 [Full Text]  
• Aspelin, P., Aubry, P., Fransson, S.-G., Strasser, R., Willenbrock, R., Berg, K. J., the NEPHRIC Study Investigators, (2003). Nephrotoxic Effects in High-Risk Patients Undergoing Angiography. NEJM 348: 491-499 [Abstract] [Full Text]  
• Kay, J., Chow, W. H., Chan, T. M., Lo, S. K., Kwok, O. H., Yip, A., Fan, K., Lee, C. H., Lam, W. F. (2003). Acetylcysteine for Prevention of Acute Deterioration of Renal Function Following Elective Coronary Angiography and Intervention: A Randomized Controlled Trial. JAMA 289: 553-558 [Abstract] [Full Text]  
• Curhan, G. C. (2003). Prevention of Contrast Nephropathy. JAMA 289: 606-608 [Full Text]  
• Mehta, R. L., Pascual, M. T., Soroko, S., Chertow, G. M., for the PICARD Study Group, (2002). Diuretics, Mortality, and Nonrecovery of Renal Function in Acute Renal Failure. JAMA 288: 2547-2553 [Abstract] [Full Text]  
• Kapoor, A., Kumar, S., Gulati, S., Gambhir, S., Sethi, R. S., Sinha, N. (2002). The role of theophylline in contrast-induced nephropathy: a case-control study. Nephrol Dial Transplant 17: 1936-1941 [Abstract] [Full Text]  
• Shyu, K.-G. i, Cheng, J.-J., Kuan, P. (2002). Acetylcysteine protects against acute renal damage in patients with abnormal renal function undergoing a coronary procedure. J Am Coll Cardiol 40: 1383-1388 [Abstract] [Full Text]  
• Chamsuddin, A. A., Kowalik, K. J., Bjarnason, H., Dietz, C. A., Rosenberg, M. S., Gomes, M. D., McDermott, C. M., Hunter, D. W. (2002). Using a Dopamine Type IA Receptor Agonist in High-Risk Patients to Ameliorate Contrast-Associated Nephropathy. Am. J. Roentgenol. 179: 591-596 [Abstract] [Full Text]  
• Esnault, V. L. M. (2002). Radiocontrast media-induced nephrotoxicity in patients with renal failure: rationale for a new double-blind, prospective, randomized trial testing calcium channel antagonists. Nephrol Dial Transplant 17: 1362-1364 [Full Text]  
• Briguori, C., Manganelli, F., Scarpato, P., Elia, P. P., Golia, B., Riviezzo, G., Lepore, S., Librera, M., Villari, B., Colombo, A., Ricciardelli, B. (2002). Acetylcysteine and contrast agent-associated nephrotoxicity. J Am Coll Cardiol 40: 298-303 [Abstract] [Full Text]  
• Huber, W., Ilgmann, K., Page, M., Hennig, M., Schweigart, U., Jeschke, B., Lutilsky, L., Weiss, W., Salmhofer, H., Classen, M. (2002). Effect of Theophylline on Contrast Material-induced Nephropathy in Patients with Chronic Renal Insufficiency: Controlled, Randomized, Double-blinded Study. Radiology 223: 772-779 [Abstract] [Full Text]  
• Rieger, J., Sitter, T., Toepfer, M., Linsenmaier, U., Pfeifer, K. J., Schiffl, H. (2002). Gadolinium as an alternative contrast agent for diagnostic and interventional angiographic procedures in patients with impaired renal function. Nephrol Dial Transplant 17: 824-828 [Abstract] [Full Text]  
• Spinosa, D. J., Kaufmann, J. A., Hartwell, G. D. (2002). Gadolinium Chelates in Angiography and Interventional Radiology: A Useful Alternative to Iodinated Contrast Media for Angiography. Radiology 223: 319-325 [Abstract] [Full Text]  
• Mueller, C., Buerkle, G., Buettner, H. J., Petersen, J., Perruchoud, A. P., Eriksson, U., Marsch, S., Roskamm, H. (2002). Prevention of Contrast Media-Associated Nephropathy: Randomized Comparison of 2 Hydration Regimens in 1620 Patients Undergoing Coronary Angioplasty. Arch Intern Med 162: 329-336 [Abstract] [Full Text]  
• BLOCK, C. A., MANNING, H. L. (2002). Prevention of Acute Renal Failure in the Critically Ill. Am. J. Respir. Crit. Care Med. 165: 320-324 [Full Text]  
• Kessel, D O, Robertson, I, Patel, J V, Simpson, S, Taylor, E J (2001). Angiographic strategies when iodinated contrast medium is undesirable. Imaging 13: 349-356 [Abstract] [Full Text]  
• Schindler, R., Stahl, C., Venz, S., Ludat, K., Krause, W., Frei, U. (2001). Removal of contrast media by different extracorporeal treatments. Nephrol Dial Transplant 16: 1471-1474 [Abstract] [Full Text]  
• Bassilios, N., Mercadal, L., Deray, G. (2001). Immunoglobulin as a risk factor for contrast media nephrotoxicity. Nephrol Dial Transplant 16: 1513-1514 [Full Text]  
• Elsner, D. (2001). How to diagnose and treat coronary artery disease in the uraemic patient: an update. Nephrol Dial Transplant 16: 1103-1108 [Full Text]  
• Spinosa, D. J., Matsumoto, A. H., Angle, J. F., Hagspiel, K. D., Cage, D., Bissonette, E. A., Koenig, K. G., Ayers, C. R., McConnell, K. (2001). Safety of CO2- and Gadodiamide-Enhanced Angiography for the Evaluation and Percutaneous Treatment of Renal Artery Stenosis in Patients with Chronic Renal Insufficiency. Am. J. Roentgenol. 176: 1305-1311 [Abstract] [Full Text]  
• Hauptman, P. J., O'Connor, K. J., Wolf, R. E., McNeil, B. J. (2001). Angiography of potential cardiac donors. J Am Coll Cardiol 37: 1252-1258 [Abstract] [Full Text]  
• BAKER, C S R, BAKER, L R I (2001). Prevention of contrast nephropathy after cardiac catheterisation. Heart 85: 361-362 [Full Text]  
• Laisalmi, M., Eriksson, H., Koivusalo, A.-M., Pere, P., Rosenberg, P., Lindgren, MD, L. (2001). Ketorolac is Not Nephrotoxic in Connection with Sevoflurane Anesthesia in Patients Undergoing Breast Surgery. Anesth. Analg. 92: 1058-1063 [Abstract] [Full Text]  
• Gruberg, L., Mintz, G. S., Mehran, R., Dangas, G., Lansky, A. J., Kent, K. M., Pichard, A. D., Satler, L. F., Leon, M. B. (2000). The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency. J Am Coll Cardiol 36: 1542-1548 [Abstract] [Full Text]