Background Coronary-artery stents are known to reduce ratesof restenosis after coronary angioplasty, but it is uncertainhow long this benefit is maintained.
Methods We evaluated clinical and angiographic follow-up informationfor up to three years after the implantation of PalmazSchatzmetallic coronary-artery stents in 143 patients with 147 lesionsof native coronary arteries.
Results The rate of survival free of myocardial infarction,bypass surgery, and repeated coronary angioplasty for stentedlesions was 74.6 percent at three years. After 14 months, revascularizationof the stented lesion was necessary in only three patients (2.1percent). In contrast, coronary angioplasty for a new lesionwas required in 11 patients (7.7 percent). Follow-up coronaryangiography of 137 lesions at six months, 114 lesions at oneyear, and 72 lesions at three years revealed a decrease in minimalluminal diameter from 2.54±0.44 mm immediately afterstent implantation to 1.87±0.56 mm at six months, butno further decrease in diameter at one year (in patients withpaired angiograms, 1.95±0.49 mm at both six months andone year). Significant late improvement in luminal diameterwas observed at three years (in patients with paired angiograms,1.94±0.48 mm at six months and 2.09±0.48 mm atthree years; P<0.001).
Conclusions Clinical and angiographic outcomes up to three yearsafter coronary-artery stenting were favorable, with a low rateof revascularization of the stented lesions. Late improvementin luminal diameter appears to occur between six months andthree years.
Source Information
From the Department of Cardiology, Kokura Memorial Hospital, 1-1 Kifune-machi, Kokurakita-ku, Kitakyushu, 802, Japan, where reprint requests should be addressed to Dr. Nobuyoshi.
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