Background Right ventricular infarction occurs in conjunctionwith inferior myocardial infarction caused by proximal occlusionof the right coronary artery. However, right ventricular infarctionoccurs infrequently, and the reasons for this are uncertain.
Methods We retrospectively assessed the association betweenpreinfarction angina and right ventricular infarction, as wellas the short-term outcome, in 113 patients with a first acuteinferior myocardial infarction caused by right-coronary-arteryocclusion. The association between the timing of angina duringthe week before infarction and the clinical outcome was alsoassessed.
Results The absence of preinfarction angina predicted the developmentof right ventricular infarction (odds ratio, 6.3; 95 percentconfidence interval, 2.7 to 15.1; P<0.001), complete atrioventricularblock (odds ratio, 3.6; 95 percent confidence interval, 1.4to 10.3; P = 0.01), and combined hypotension and shock (oddsratio, 12.4; 95 percent confidence interval, 4.5 to 40.6; P<0.001).Angina 24 to 72 hours before infarction was most strongly associatedwith reductions in the rates of right ventricular infarction(adjusted odds ratio, 0.2; 95 percent confidence interval, 0to 0.8; P = 0.02) and combined hypotension and shock (adjustedodds ratio, 0.1; 95 percent confidence interval, 0 to 0.5; P= 0.02).
Conclusions Preinfarction angina was an independent predictorof the absence of right ventricular infarction in patients withacute inferior myocardial infarction. The patients with preinfarctionangina also had better short-term outcomes than those withoutpreinfarction angina.
Source Information
From the Department of Cardiology, Yokohama Municipal Hospital, Yokohama (H.S., K.N., T.T.); and the Department of Internal Medicine, Keio University School of Medicine, Tokyo (T.Y., T.A., Y.A., M.A., H.M., S.O.) both in Japan.
Address reprint requests to Dr. Shiraki at the Department of Cardiology, Yokohama Municipal Hospital, 56 Okazawa-cho Hodogaya-ku, Yokohama 240-0062, Japan.
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