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Previous Volume 340:847-851 March 18, 1999 Number 11 Next

	Full Text PDF Editorial by Suratt, P. M. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

ABSTRACT

Background and Methods Drowsiness and lack of concentration may contribute to traffic accidents. We conducted a case–control study of the relation between sleep apnea and the risk of traffic accidents. The case patients were 102 drivers who received emergency treatment at hospitals in Burgos or Santander, Spain, after highway traffic accidents between April and December 1995. The controls were 152 patients randomly selected from primary care centers in the same cities and matched with the case patients for age and sex. Respiratory polygraphy was used to screen the patients for sleep apnea at home, and conventional polysomnography was used to confirm the diagnosis. The apnea–hypopnea index (the total number of episodes of apnea and hypopnea divided by the number of hours of sleep) was calculated for each participant.

Results The mean age of the participants was 44 years; 77 percent were men. As compared with those without sleep apnea, patients with an apnea–hypopnea index of 10 or higher had an odds ratio of 6.3 (95 percent confidence interval, 2.4 to 16.2) for having a traffic accident. This relation remained significant after adjustment for potential confounders, such as alcohol consumption, visual-refraction disorders, body-mass index, years of driving, age, history with respect to traffic accidents, use of medications causing drowsiness, and sleep schedule. Among subjects with an apnea–hypopnea index of 10 or more, the risk of an accident was higher among those who had consumed alcohol on the day of the accident than among those who had not.

Conclusions There is a strong association between sleep apnea, as measured by the apnea–hypopnea index, and the risk of traffic accidents.

Source Information

From the General Yagüe Hospital, Burgos (J.T.-S., J.C.-G.); and the Marqués de Valdecilla University Hospital, Santander (A.J.-G.) — both in Spain.

Address reprint requests to Dr. Jiménez at H.U.M. de Valdecilla, Servicio de Respiratorio, Avda. de Valdecilla s/n, 3900 Santander, Spain, or at nmljga{at}humv.es.

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• Mulgrew, A T, Nasvadi, G, Butt, A, Cheema, R, Fox, N, Fleetham, J A, Ryan, C F, Cooper, P, Ayas, N T (2008). Risk and severity of motor vehicle crashes in patients with obstructive sleep apnoea/hypopnoea. Thorax 63: 536-541 [Abstract] [Full Text]  
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• George, C. F. P. (2007). Sleep Apnea, Alertness, and Motor Vehicle Crashes. Am. J. Respir. Crit. Care Med. 176: 954-956 [Abstract] [Full Text]  
• Ahmed, M., Patel, N. P., Rosen, I. (2007). Portable Monitors in the Diagnosis of Obstructive Sleep Apnea. Chest 132: 1672-1677 [Abstract] [Full Text]  
• Montserrat, J. M., Garcia-Rio, F., Barbe, F. (2007). Diagnostic and Therapeutic Approach to Nonsleepy Apnea. Am. J. Respir. Crit. Care Med. 176: 6-9 [Abstract] [Full Text]  
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• McNicholas, W. T., Bonsignore, M. R., the Management Committee of EU COST ACTION B26, (2007). Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 29: 156-178 [Abstract] [Full Text]  
• Czeisler, C. A., Gooley, J. J. (2007). Sleep and Circadian Rhythms in Humans. Cold Spring Harb Symp Quant Biol 72: 579-597 [Abstract]  
• Edmonds, J. N., Vinson, D. C. (2007). Three Measures of Sleep, Sleepiness, and Sleep Deprivation and the Risk of Injury: A Case-Control and Case-Crossover Study. J Am Board Fam Med 20: 16-22 [Abstract] [Full Text]  
• Mazza, S., Pepin, J-L., Naegele, B., Rauch, E., Deschaux, C., Ficheux, P., Levy, P. (2006). Driving ability in sleep apnoea patients before and after CPAP treatment: evaluation on a road safety platform. Eur Respir J 28: 1020-1028 [Abstract] [Full Text]  
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• Plainis, S, Murray, I J, Pallikaris, I G (2006). Road traffic casualties: understanding the night-time death toll.. Inj. Prev. 12: 125-138 [Abstract] [Full Text]  
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• Turkington, P M, Sircar, M, Saralaya, D, Elliott, M W (2004). Time course of changes in driving simulator performance with and without treatment in patients with sleep apnoea hypopnoea syndrome. Thorax 59: 56-59 [Abstract] [Full Text]  
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• Patel, S. R., White, D. P., Malhotra, A., Stanchina, M. L., Ayas, N. T. (2003). Continuous Positive Airway Pressure Therapy for Treating gess in a Diverse Population With Obstructive Sleep Apnea: Results of a Meta-analysis. Arch Intern Med 163: 565-571 [Abstract] [Full Text]  
• Mar, J., Rueda, J.R., Duran-Cantolla, J., Schechter, C., Chilcott, J. (2003). The cost-effectiveness of nCPAP treatment in patients with moderate-to-severe obstructive sleep apnoea. Eur Respir J 21: 515-522 [Abstract] [Full Text]  
• Dingli, K., Coleman, E.L., Vennelle, M., Finch, S.P., Wraith, P.K., Mackay, T.W., Douglas, N.J. (2003). Evaluation of a portable device for diagnosing the sleep apnoea/hypopnoea syndrome. Eur Respir J 21: 253-259 [Abstract] [Full Text]  
• Whitlock, G., Norton, R., Clark, T., Jackson, R., MacMahon, S. (2003). Is body mass index a risk factor for motor vehicle driver injury? A cohort study with prospective and retrospective outcomes. Int J Epidemiol 32: 147-149 [Abstract] [Full Text]  
• (2003). Rebuttal from Dr. Black. Am. J. Respir. Crit. Care Med. 167: 107-108 [Full Text]  
• Marti, S., Sampol, G., Munoz, X., Torres, F., Roca, A., Lloberes, P., Sagales, T., Quesada, P., Morell, F. (2002). Mortality in severe sleep apnoea/hypopnoea syndrome patients: impact of treatment. Eur Respir J 20: 1511-1518 [Abstract] [Full Text]  
• Sin, D. D., Mayers, I., Man, G. C.W., Ghahary, A., Pawluk, L. (2002). Can Continuous Positive Airway Pressure Therapy Improve the General Health Status of Patients With Obstructive Sleep Apnea?: A Clinical Effectiveness Study. Chest 122: 1679-1685 [Abstract] [Full Text]  
• Golpe, R., Jimenez, A., Carpizo, R. (2002). Home Sleep Studies in the Assessment of Sleep Apnea/Hypopnea Syndrome. Chest 122: 1156-1161 [Abstract] [Full Text]  
• Dingli, K., Fietze, I., Assimakopoulos, T., Quispe-Bravo, S., Witt, C., Douglas, N.J. (2002). Arousability in sleep apnoea/hypopnoea syndrome patients. Eur Respir J 20: 733-740 [Abstract] [Full Text]  
• Schafer, H., Pauleit, D., Sudhop, T., Gouni-Berthold, I., Ewig, S., Berthold, H. K. (2002). Body Fat Distribution, Serum Leptin, and Cardiovascular Risk Factors in Men With Obstructive Sleep Apnea*. Chest 122: 829-839 [Abstract] [Full Text]  
• Boyer, S., Kapur, V. (2002). Obstructive Sleep Apnea: Its Relevance in the Care of Diabetic Patients. Clin. Diabetes 20: 126-132 [Abstract] [Full Text]  
• Namen, A. M., Dunagan, D. P., Fleischer, A., Tillett, J., Barnett, M., McCall, W. V., Haponik, E. F. (2002). Increased Physician-Reported Sleep Apnea* : The National Ambulatory Medical Care Survey. Chest 121: 1741-1747 [Abstract] [Full Text]  
• Connor, J., Norton, R., Ameratunga, S., Robinson, E., Civil, I., Dunn, R., Bailey, J., Jackson, R. (2002). Driver sleepiness and risk of serious injury to car occupants: population based case control study. BMJ 324: 1125-1125 [Abstract] [Full Text]  
• Young, T., Peppard, P. E., Gottlieb, D. J. (2002). Epidemiology of Obstructive Sleep Apnea: A Population Health Perspective. Am. J. Respir. Crit. Care Med. 165: 1217-1239 [Abstract] [Full Text]  
• George, C. F. P., Findley, L. J., Hack, M. A., McEvoy, R. D. (2002). Across-Country Viewpoints on Sleepiness during Driving. Am. J. Respir. Crit. Care Med. 165: 746-749 [Full Text]  
• Garrigue, S., Bordier, P., Jais, P., Shah, D. C., Hocini, M., Raherison, C., Tunon De Lara, M., Haissaguerre, M., Clementy, J. (2002). Benefit of Atrial Pacing in Sleep Apnea Syndrome. NEJM 346: 404-412 [Abstract] [Full Text]  
• FOGEL, R. B., MALHOTRA, A., PILLAR, G., EDWARDS, J. K., BEAUREGARD, J., SHEA, S. A., WHITE, D. P. (2001). Genioglossal Activation in Patients with Obstructive Sleep Apnea versus Control Subjects . Mechanisms of Muscle Control. Am. J. Respir. Crit. Care Med. 164: 2025-2030 [Abstract] [Full Text]  
• PACK, A. I., BLACK, J. E., SCHWARTZ, J. R. L., MATHESON, J. K. (2001). Modafinil as Adjunct Therapy for Daytime Sleepiness in Obstructive Sleep Apnea. Am. J. Respir. Crit. Care Med. 164: 1675-1681 [Abstract] [Full Text]  
• Turkington, P M, Sircar, M, Allgar, V, Elliott, M W (2001). Relationship between obstructive sleep apnoea, driving simulator performance, and risk of road traffic accidents. Thorax 56: 800-805 [Abstract] [Full Text]  
• MONASTERIO, C., VIDAL, S., DURAN, J., FERRER, M., CARMONA, C., BARBE, F., MAYOS, M., GONZALEZ-MANGADO, N., JUNCADELLA, M., NAVARRO, A., BARREIRA, R., CAPOTE, F., MAYORALAS, L. R., PECES-BARBA, G., ALONSO, J., MONTSERRAT, J. M. (2001). Effectiveness of Continuous Positive Airway Pressure in Mild Sleep Apnea-Hypopnea Syndrome. Am. J. Respir. Crit. Care Med. 164: 939-943 [Abstract] [Full Text]  
• Cummings, P, Koepsell, T D, Moffat, J M, Rivara, F P (2001). Drowsiness, counter-measures to drowsiness, and the risk of a motor vehicle crash. Inj. Prev. 7: 194-199 [Abstract] [Full Text]  
• Douglas, N. J (2001). THE SLEEPY PATIENT. J. Neurol. Neurosurg. Psychiatry 71: i3-i6 [Full Text]  
• Popescu, G, Latham, M, Allgar, V, Elliott, M W (2001). Continuous positive airway pressure for sleep apnoea/hypopnoea syndrome: usefulness of a 2 week trial to identify factors associated with long term use. Thorax 56: 727-733 [Abstract] [Full Text]  
• George, C F P (2001). Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP. Thorax 56: 508-512 [Abstract] [Full Text]  
• Pack, A. I., Maislin, G. (2001). Who Should Get Treated for Sleep Apnea?. ANN INTERN MED 134: 1065-1067 [Full Text]  
• Mena Gutierrez, A.L., Rodenstein, D.O. (2001). The search for the Holy Grail and the upper airway resistance syndrome. New data are welcome. Eur Respir J 17: 835-837 [Full Text]  
• DURAN, J., ESNAOLA, S., RUBIO, R., IZTUETA, A. (2001). Obstructive Sleep Apnea-Hypopnea and Related Clinical Features in a Population-based Sample of Subjects Aged 30 to 70 Yr. Am. J. Respir. Crit. Care Med. 163: 685-689 [Abstract] [Full Text]  
• FACCENDA, J. F., MACKAY, T. W., BOON, N. A., DOUGLAS, N. J. (2001). Randomized Placebo-controlled Trial of Continuous Positive Airway Pressure on Blood Pressure in the Sleep Apnea-Hypopnea Syndrome. Am. J. Respir. Crit. Care Med. 163: 344-348 [Abstract] [Full Text]  
• Ip, M. S. M., Lam, B., Lauder, I. J., Tsang, K. W. T., Chung, K.-f., Mok, Y.-w., Lam, W.-k. (2001). A Community Study of Sleep-Disordered Breathing in Middle-aged Chinese Men in Hong Kong. Chest 119: 62-69 [Abstract] [Full Text]  
• Staniforth, A D, Kinnear, W J M, Cowley, A J (2001). Cognitive impairment in heart failure with Cheyne-Stokes respiration. Heart 85: 18-22 [Abstract] [Full Text]  
• Peppard, P. E., Young, T., Palta, M., Dempsey, J., Skatrud, J. (2000). Longitudinal Study of Moderate Weight Change and Sleep-Disordered Breathing. JAMA 284: 3015-3021 [Abstract] [Full Text]  
• MASA, J. F., RUBIO, M., FINDLEY, L. J. (2000). Habitually Sleepy Drivers Have a High Frequency of Automobile Crashes Associated with Respiratory Disorders during Sleep. Am. J. Respir. Crit. Care Med. 162: 1407-1412 [Abstract] [Full Text]  
• Blankfield, R. P., Hudgel, D. W., Tapolyai, A. A., Zyzanski, S. J. (2000). Bilateral Leg Edema, Obesity, Pulmonary Hypertension, and Obstructive Sleep Apnea. Arch Intern Med 160: 2357-2362 [Abstract] [Full Text]  
• FRIEDLANDER, A. H., WALKER, L. A., FRIEDLANDER, I. K., FELSENFELD, A. L. (2000). DIAGNOSING AND COMANAGING PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME. Journal of the American Dental Association 131: 1178-1184 [Abstract] [Full Text]  
• Hack, M., Davies, R. J O, Mullins, R., Choi, S. J., Ramdassingh-Dow, S., Jenkinson, C., Stradling, J. R (2000). Randomised prospective parallel trial of therapeutic versus subtherapeutic nasal continuous positive airway pressure on simulated steering performance in patients with obstructive sleep apnoea. Thorax 55: 224-231 [Abstract] [Full Text]  
• McAbee, G., Madison, A., Drachman, D. A., Krauss, G. L., Krumholz, A., Li, G. (1999). Risk factors for seizure-related motor vehicle crashes in patients with epilepsy. Neurology 53: 2211-2211 [Full Text]  
• Loube, D. I. (1999). Technologic Advances in the Treatment of Obstructive Sleep Apnea Syndrome. Chest 116: 1426-1433 [Abstract] [Full Text]  
• (1999). Sleep Apnea and Traffic Accidents. JWatch Psychiatry 1999: 5-5 [Full Text]  
• (1999). Sleep Apnea and Risk for Traffic Accidents. JWatch General 1999: 3-3 [Full Text]  
• Suratt, P. M., Findley, L. J. (1999). Driving with Sleep Apnea. NEJM 340: 881-883 [Full Text]