Coverage by the News Media of the Benefits and Risks of Medications
Ray Moynihan, B.A., Lisa Bero, Ph.D., Dennis Ross-Degnan, Sc.D., David Henry, M.B., Ch.B., Kirby Lee, M.A., Judy Watkins, B.A., Connie Mah, B.A., and Stephen B. Soumerai, Sc.D.
Background The news media are an important source of informationabout new medical treatments, but there is concern that somecoverage may be inaccurate and overly enthusiastic.
Methods We studied coverage by U.S. news media of the benefitsand risks of three medications that are used to prevent majordiseases. The medications were pravastatin, a cholesterol-loweringdrug for the prevention of cardiovascular disease; alendronate,a bisphosphonate for the treatment and prevention of osteoporosis;and aspirin, which is used for the prevention of cardiovasculardisease. We analyzed a systematic probability sample of 180newspaper articles (60 for each drug) and 27 television reportsthat appeared between 1994 and 1998.
Results Of the 207 stories, 83 (40 percent) did not report benefitsquantitatively. Of the 124 that did, 103 (83 percent) reportedrelative benefits only, 3 (2 percent) absolute benefits only,and 18 (15 percent) both absolute and relative benefits. Ofthe 207 stories, 98 (47 percent) mentioned potential harm topatients, and only 63 (30 percent) mentioned costs. Of the 170stories citing an expert or a scientific study, 85 (50 percent)cited at least one expert or study with a financial tie to amanufacturer of the drug that had been disclosed in the scientificliterature. These ties were disclosed in only 33 (39 percent)of the 85 stories.
Conclusions News-media stories about medications may includeinadequate or incomplete information about the benefits, risks,and costs of the drugs as well as the financial ties betweenstudy groups or experts and pharmaceutical manufacturers.
Source Information
From the Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston (R.M., D.R.-D., C.M., S.B.S.); the Australian Broadcasting Corporation, Sydney, N.S.W., Australia (R.M.); the Department of Clinical Pharmacy, School of Pharmacy (L.B., K.L.), and Institute for Health Policy Studies, School of Medicine (L.B.), University of California, San Francisco; and the School of Population Health Sciences, Faculty of Medicine and Health Sciences, University of Newcastle, Newcastle, N.S.W., Australia (D.H.).
Address reprint requests to Dr. Soumerai at the Department of Ambulatory Care and Prevention, Harvard Medical School, 126 Brookline Ave., Suite 200, Boston, MA 02215, or at ssoumerai{at}hms.harvard.edu.
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