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Volume 345:779-783 September 13, 2001 Number 11 Next

	Full Text PDF Editorial by Ansell, J. E. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

ABSTRACT

Background Air travel is believed to be a risk factor for pulmonary embolism, but the relation between pulmonary embolism and distance flown has not been documented. The aim of this study was to investigate whether the duration of air travel is related to the risk of pulmonary embolism.

Methods From November 1993 to December 2000, we systematically reviewed all cases of pulmonary embolism requiring medical care on arrival at France's busiest international airport. Data on the geographic origins of all flights and the numbers of passengers were collected in order to evaluate the incidence of pulmonary embolism per million passenger arrivals as a function of the distance traveled.

Results A total of 135.29 million passengers from 145 countries or other areas arrived at Charles de Gaulle Airport during the period of the study, of whom 56 had confirmed pulmonary embolism. The incidence of pulmonary embolism was much higher among passengers traveling more than 5000 km (3100 mi) (1.5 cases per million, as compared with 0.01 case per million among those traveling less than 5000 km). The incidence of pulmonary embolism was 4.8 cases per million for those traveling more than 10,000 km (6200 mi).

Conclusions A greater distance traveled is a significant contributing risk factor for pulmonary embolism associated with air travel.

Source Information

From Service d'Aide Médicale Urgente (SAMU) 93, Hôpital Avicenne, Université Paris XIII, Bobigny, France (F.L., V.S., S.W.B., M.D., D.S., C.L., M.C., F.A.); and the Department of Emergency Medicine and the Division of Occupational and Environmental Health, George Washington University School of Medicine, Washington, D.C. (S.W.B.).

Address reprint requests to Dr. Lapostolle at SAMU 93, Hôpital Avicenne, 125 rue de Stalingrad, 93009 Bobigny, France, or at frederic.lapostolle{at}avc.ap-hop-paris.fr.

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