A Controlled Trial of Inpatient and Outpatient Geriatric Evaluation and Management
Harvey Jay Cohen, M.D., John R. Feussner, M.D., Morris Weinberger, Ph.D., Molly Carnes, M.D., Ronald C. Hamdy, M.D., Frank Hsieh, Ph.D., Ciaran Phibbs, Ph.D., Donald Courtney, M.D., Kenneth W. Lyles, M.D., Conrad May, M.D., Cynthia McMurtry, M.D., Leslye Pennypacker, M.D., David M. Smith, M.D., Nina Ainslie, M.D., Thomas Hornick, M.D., Kayla Brodkin, M.D., and Philip Lavori, Ph.D.
Background Over the past 20 years, both inpatient units andoutpatient clinics have developed programs for geriatric evaluationand management. However, the effects of these interventionson survival and functional status remain uncertain.
Methods We conducted a randomized trial involving frail patients65 years of age or older who were hospitalized at 11 VeteransAffairs medical centers. After their condition had been stabilized,patients were randomly assigned, according to a two-by-two factorialdesign, to receive either care in an inpatient geriatric unitor usual inpatient care, followed by either care at an outpatientgeriatric clinic or usual outpatient care. The interventionsinvolved teams that provided geriatric assessment and managementaccording to Veterans Affairs standards and published guidelines.The primary outcomes were survival and health-related qualityof life, measured with the use of the Medical Outcomes Study36-Item Short-Form General Health Survey (SF-36), one year afterrandomization. Secondary outcomes were the ability to performactivities of daily living, physical performance, utilizationof health services, and costs.
Results A total of 1388 patients were enrolled and followed.Neither the inpatient nor the outpatient intervention had asignificant effect on mortality (21 percent at one year overall),nor were there any synergistic effects between the two interventions.At discharge, patients assigned to the inpatient geriatric unitshad significantly greater improvements in the scores for fourof the eight SF-36 subscales, activities of daily living, andphysical performance than did those assigned to usual inpatientcare. At one year, patients assigned to the outpatient geriatricclinics had better scores on the SF-36 mental health subscale,even after adjustment for the score at discharge, than thoseassigned to usual outpatient care. Total costs at one year weresimilar for the intervention and usual-care groups.
Conclusions In this controlled trial, care provided in inpatientgeriatric units and outpatient geriatric clinics had no significanteffects on survival. There were significant reductions in functionaldecline with inpatient geriatric evaluation and management andimprovements in mental health with outpatient geriatric evaluationand management, with no increase in costs.
Source Information
From the Veterans Affairs Medical Center, Durham, N.C. (H.J.C.); the Veterans Affairs Central Office, Washington, D.C. (J.R.F.); the Veterans Affairs Medical Center, Indianapolis (M.W.); the Veterans Affairs Medical Center, Madison, Wis. (M.C.); the Veterans Affairs Medical Center, Mt. Home, Tenn. (R.C.H.); and the Veterans Affairs Cooperative Studies Program Coordinating Center, Palo Alto, Calif. (F.H., C.P., P.L.). Other authors were Donald Courtney, M.D., Veterans Affairs Medical Center, Leavenworth, Kans.; Kenneth W. Lyles, M.D., Veterans Affairs Medical Center, Durham, N.C.; Conrad May, M.D., Veterans Affairs Medical Center, Baltimore; Cynthia McMurtry, M.D., Veterans Affairs Medical Center, Richmond, Va.; Leslye Pennypacker, M.D., Veterans Affairs Medical Center, Charleston, S.C.; David M. Smith, M.D., Veterans Affairs Medical Center, Indianapolis; Nina Ainslie, M.D., Veterans Affairs Medical Center, Kansas City, Mo.; Thomas Hornick, M.D., Veterans Affairs Medical Center, Cleveland; and Kayla Brodkin, M.D., Veterans Affairs Medical Center, Seattle.
Address reprint requests to Dr. Cohen at the Veterans Affairs Medical Center, 508 Fulton St., Durham, NC 27705.
A Controlled Trial of Geriatric Evaluation
Stuck A. E., Egger M., Beck J. C., Bernabei R., Gambassi G., Carbonin P., Nikolaus T., Becker C., Meuleman J., Cohen H. J., Weinberger M., Feussner J. R.
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N Engl J Med 2002;
347:371-373, Aug 1, 2002.
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