FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 352:1436-1444 April 7, 2005 Number 14 Next

	Full Text PDF PDA Full Text PowerPoint Slide Set Supplementary Material Editorial by Chambers, H. F. Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article PubMed Citation

ABSTRACT

Background Methicillin-resistant Staphylococcus aureus (MRSA) infection has emerged in patients who do not have the established risk factors. The national burden and clinical effect of this novel presentation of MRSA disease are unclear.

Methods We evaluated MRSA infections in patients identified from population-based surveillance in Baltimore and Atlanta and from hospital-laboratory–based sentinel surveillance of 12 hospitals in Minnesota. Information was obtained by interviewing patients and by reviewing their medical records. Infections were classified as community-acquired MRSA disease if no established risk factors were identified.

Results From 2001 through 2002, 1647 cases of community-acquired MRSA infection were reported, representing between 8 and 20 percent of all MRSA isolates. The annual disease incidence varied according to site (25.7 cases per 100,000 population in Atlanta vs. 18.0 per 100,000 in Baltimore) and was significantly higher among persons less than two years old than among those who were two years of age or older (relative risk, 1.51; 95 percent confidence interval, 1.19 to 1.92) and among blacks than among whites in Atlanta (age-adjusted relative risk, 2.74; 95 percent confidence interval, 2.44 to 3.07). Six percent of cases were invasive, and 77 percent involved skin and soft tissue. The infecting strain of MRSA was often (73 percent) resistant to prescribed antimicrobial agents. Among patients with skin or soft-tissue infections, therapy to which the infecting strain was resistant did not appear to be associated with adverse patient-reported outcomes. Overall, 23 percent of patients were hospitalized for the MRSA infection.

Conclusions Community-associated MRSA infections are now a common and serious problem. These infections usually involve the skin, especially among children, and hospitalization is common.

Source Information

From the Division of Bacterial and Mycotic Diseases (S.K.F.) and Division of Healthcare Quality Promotion (J.C.H., M.M., J.A.J.), National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta; Emory University School of Medicine and the Veterans Affairs Medical Center, Atlanta (M.M., J.A.J., M.M.F.); Johns Hopkins University Bloomberg School of Public Health, Baltimore (L.T.S., L.H.H.); and the Minnesota Department of Health, Minneapolis (K.C.-S., K.H., R.L.).

Address reprint requests to Dr. Fridkin at the CDC, NCID, DBMD, MDB, MS C-09, 1600 Clifton Rd., NE, Atlanta, GA 30333, or at skf0{at}cdc.gov.

Full Text of this Article

Related Letters:

MRSA in the Community
Chapman A. L.N., Greig J. M., Innes J. A., Hageman J. C., Lynfield R., Fridkin S. K., Miller L. G., Perdreau-Remington F., Spellberg B.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:530-532, Aug 4, 2005. Correspondence

This article has been cited by other articles:

• Deger, G. E., Quick, D. W. (2009). The Enduring Menace of MRSA: Incidence, Treatment, and Prevention in a County Jail. J Correct Health Care 15: 174-178 [Abstract]  
• Parta, M., Goebel, M., Matloobi, M., Stager, C., Musher, D. M. (2009). Identification of Methicillin-Resistant or Methicillin-Susceptible Staphylococcus aureus in Blood Cultures and Wound Swabs by GeneXpert. J. Clin. Microbiol. 47: 1609-1610 [Full Text]  
• Trinh, T. T., Short, W. R., Mermel, L. A. (2009). Community-Associated Methicillin-Resistant Staphylococcus aureus Skin and Soft-Tissue Infection in HIV-Infected Patients. J Int Assoc Physicians AIDS Care (Chic Ill) 8: 176-180 [Abstract]  
• Ellis, M. W., Griffith, M. E., Jorgensen, J. H., Hospenthal, D. R., Mende, K., Patterson, J. E. (2009). Presence and Molecular Epidemiology of Virulence Factors in Methicillin-Resistant Staphylococcus aureus Strains Colonizing and Infecting Soldiers. J. Clin. Microbiol. 47: 940-945 [Abstract] [Full Text]  
• Many, P. S. (2008). Preventing Community-Associated Methicillin-Resistant Staphylococcus aureus Among Student Athletes. The Journal of School Nursing 24: 370-378 [Abstract] [Full Text]  
• Rehm, S. J., Boucher, H., Levine, D., Campion, M., Eisenstein, B. I., Vigliani, G. A., Corey, G.R., Abrutyn, E. (2008). Daptomycin versus vancomycin plus gentamicin for treatment of bacteraemia and endocarditis due to Staphylococcus aureus: subset analysis of patients infected with methicillin-resistant isolates. J Antimicrob Chemother 62: 1413-1421 [Abstract] [Full Text]  
• Leonard, S. N., Kaatz, G. W., Rucker, L. R., Rybak, M. J. (2008). Synergy between gemifloxacin and trimethoprim/sulfamethoxazole against community-associated methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother 62: 1305-1310 [Abstract] [Full Text]  
• Pakyz, A. L., MacDougall, C., Oinonen, M., Polk, R. E. (2008). Trends in Antibacterial Use in US Academic Health Centers: 2002 to 2006. Arch Intern Med 168: 2254-2260 [Abstract] [Full Text]  
• Dai, C., Ma, Y., Zhao, Z., Zhao, R., Wang, Q., Wu, Y., Cao, Z., Li, W. (2008). Mucroporin, the First Cationic Host Defense Peptide from the Venom of Lychas mucronatus. Antimicrob. Agents Chemother. 52: 3967-3972 [Abstract] [Full Text]  
• Patel, A., Calfee, R. P., Plante, M., Fischer, S. A., Arcand, N., Born, C. (2008). Methicillin-resistant Staphylococcus aureus in orthopaedic surgery. J Bone Joint Surg Br 90-B: 1401-1406 [Abstract] [Full Text]  
• Behlau, I., Gilmore, M. S. (2008). Microbial Biofilms in Ophthalmology and Infectious Disease. Arch Ophthalmol 126: 1572-1581 [Abstract] [Full Text]  
• Seybold, U., Halvosa, J. S., White, N., Voris, V., Ray, S. M., Blumberg, H. M. (2008). Emergence of and Risk Factors for Methicillin-Resistant Staphylococcus aureus of Community Origin in Intensive Care Nurseries. Pediatrics 122: 1039-1046 [Abstract] [Full Text]  
• Seaton, R. A. (2008). Daptomycin: rationale and role in the management of skin and soft tissue infections. J Antimicrob Chemother 62: iii15-iii23 [Abstract] [Full Text]  
• Klevens, R. M., Gorwitz, R. J., Collins, A. S. (2008). Methicillin-Resistant Staphylococcus aureus: A Primer for Dentists. Journal of the American Dental Association 139: 1328-1337 [Abstract] [Full Text]  
• Spellberg, B., Ibrahim, A. S., Yeaman, M. R., Lin, L., Fu, Y., Avanesian, V., Bayer, A. S., Filler, S. G., Lipke, P., Otoo, H., Edwards, J. E. Jr. (2008). The Antifungal Vaccine Derived from the Recombinant N Terminus of Als3p Protects Mice against the Bacterium Staphylococcus aureus. Infect. Immun. 76: 4574-4580 [Abstract] [Full Text]  
• David, M. Z., Mennella, C., Mansour, M., Boyle-Vavra, S., Daum, R. S. (2008). Predominance of Methicillin-Resistant Staphylococcus aureus among Pathogens Causing Skin and Soft Tissue Infections in a Large Urban Jail: Risk Factors and Recurrence Rates. J. Clin. Microbiol. 46: 3222-3227 [Abstract] [Full Text]  
• Wargo, K. A., Eiland, E. H. III, Eiland, L. S. (2008). Management and Treatment Considerations for Infections Caused by Methicillin-Resistant Staphylococcus aureus. Journal of Pharmacy Practice 21: 324-336 [Abstract]  
• (2008). Management of Skin and Soft-Tissue Infection. NEJM 359: 1063-1067 [Full Text]  
• Gabbay, V., Coffey, B. J., Babb, J. S., Meyer, L., Wachtel, C., Anam, S., Rabinovitz, B. (2008). Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcus: Comparison of Diagnosis and Treatment in the Community and at a Specialty Clinic. Pediatrics 122: 273-278 [Abstract] [Full Text]  
• Hersh, A. L., Chambers, H. F., Maselli, J. H., Gonzales, R. (2008). National Trends in Ambulatory Visits and Antibiotic Prescribing for Skin and Soft-Tissue Infections. Arch Intern Med 168: 1585-1591 [Abstract] [Full Text]  
• Tillotson, G. S., Draghi, D. C., Sahm, D. F., Tomfohrde, K. M., del Fabro, T., Critchley, I. A. (2008). Susceptibility of Staphylococcus aureus isolated from skin and wound infections in the United States 2005-07: laboratory-based surveillance study. J Antimicrob Chemother 62: 109-115 [Abstract] [Full Text]  
• Kim, E. S., Kim, H. B., Oh, M.-d. (2008). Survey of community-associated methicillin-resistant Staphylococcus aureus in Korea--authors' response. J Antimicrob Chemother 62: 212-213 [Full Text]  
• Laohavaleeson, S., Tessier, P. R., Nicolau, D. P. (2008). Pharmacodynamic Characterization of Ceftobiprole in Experimental Pneumonia Caused by Phenotypically Diverse Staphylococcus aureus Strains. Antimicrob. Agents Chemother. 52: 2389-2394 [Abstract] [Full Text]  
• Fritz, S. A., Garbutt, J., Elward, A., Shannon, W., Storch, G. A. (2008). Prevalence of and Risk Factors for Community-Acquired Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus Colonization in Children Seen in a Practice-Based Research Network. Pediatrics 121: 1090-1098 [Abstract] [Full Text]  
• Stauff, D. L., Bagaley, D., Torres, V. J., Joyce, R., Anderson, K. L., Kuechenmeister, L., Dunman, P. M., Skaar, E. P. (2008). Staphylococcus aureus HrtA Is an ATPase Required for Protection against Heme Toxicity and Prevention of a Transcriptional Heme Stress Response. J. Bacteriol. 190: 3588-3596 [Abstract] [Full Text]  
• Nathwani, D., Morgan, M., Masterton, R. G., Dryden, M., Cookson, B. D., French, G., Lewis, D., on behalf of the British Society for Antimicrobial, (2008). Guidelines for UK practice for the diagnosis and management of methicillin-resistant Staphylococcus aureus (MRSA) infections presenting in the community. J Antimicrob Chemother 61: 976-994 [Abstract] [Full Text]  
• Camargo, I. L. B. C., Gilmore, M. S. (2008). Staphylococcus aureus--Probing for Host Weakness?. J. Bacteriol. 190: 2253-2256 [Full Text]  
• Wright, C. T., Stocks, R. M. S., Armstrong, D. L., Arnold, S. R., Gould, H. J. (2008). Pediatric Mediastinitis as a Complication of Methicillin-Resistant Staphylococcus aureus Retropharyngeal Abscess. Arch Otolaryngol Head Neck Surg 134: 408-413 [Abstract] [Full Text]  
• Feder, H. M. Jr (2008). Occult Methicillin-Resistant Staphylococcus aureus Abscesses in 2 Pediatric Patients. CLIN PEDIATR 47: 176-179 [Abstract]  
• Maresso, A. W., Schneewind, O. (2008). Sortase as a Target of Anti-Infective Therapy. Pharmacol. Rev. 60: 128-141 [Abstract] [Full Text]  
• Gorwitz, R., Fridkin, S. K., Workowski, K. A. (2008). More Challenges in the Prevention and Management of Community-Associated, Methicillin-Resistant Staphylococcus aureus Skin Disease. ANN INTERN MED 148: 310-312 [Full Text]  
• DeLeo, F. R., Otto, M. (2008). An antidote for Staphylococcus aureus pneumonia?. JEM 205: 271-274 [Abstract] [Full Text]  
• Herman, R. A., Kee, V. R., Moores, K. G., Ross, M. B. (2008). Etiology and treatment of community-associated methicillin-resistant Staphylococcus aureus. Am J Health Syst Pharm 65: 219-225 [Abstract] [Full Text]  
• Marcotte, A. L., Trzeciak, M. A. (2008). Community-acquired Methicillin-resistant Staphylococcus aureus: An Emerging Pathogen in Orthopaedics. J Am Acad Orthop Surg 16: 98-106 [Abstract] [Full Text]  
• Campbell, S. J., Deshmukh, H. S., Nelson, C. L., Bae, I.-G., Stryjewski, M. E., Federspiel, J. J., Tonthat, G. T., Rude, T. H., Barriere, S. L., Corey, R., Fowler, V. G. Jr. (2008). Genotypic Characteristics of Staphylococcus aureus Isolates from a Multinational Trial of Complicated Skin and Skin Structure Infections. J. Clin. Microbiol. 46: 678-684 [Abstract] [Full Text]  
• Tan, T. Q. (2008). The Truth About "The Superbug," Community-Associated Methicillin-Resistant Staphylococcus aureus: What the Practicing Clinician Needs to Know. Arch Pediatr Adolesc Med 162: 183-184 [Full Text]  
• McBrien, S., Felizardo, G. R., Orr, D. G., Raymond, M. J. (2008). Using Focus Groups to Revise an Educational Booklet for People Living With Methicillin-Resistant Staphylococcus Aureus (MRSA). Health Promot Pract 9: 19-28 [Abstract]  
• Hoshino, K., Inoue, K., Murakami, Y., Kurosaka, Y., Namba, K., Kashimoto, Y., Uoyama, S., Okumura, R., Higuchi, S., Otani, T. (2008). In Vitro and In Vivo Antibacterial Activities of DC-159a, a New Fluoroquinolone. Antimicrob. Agents Chemother. 52: 65-76 [Abstract] [Full Text]  
• Shelburne, S. A. III, Singh, K. V., White, A. C. Jr., Byrne, L., Carmer, A., Austin, C., Graviss, E., Stager, C., Murray, B. E., Atmar, R. L. (2008). Sequential Outbreaks of Infections by Distinct Acinetobacter baumannii Strains in a Public Teaching Hospital in Houston, Texas. J. Clin. Microbiol. 46: 198-205 [Abstract] [Full Text]  
• Palazzolo-Ballance, A. M., Reniere, M. L., Braughton, K. R., Sturdevant, D. E., Otto, M., Kreiswirth, B. N., Skaar, E. P., DeLeo, F. R. (2008). Neutrophil Microbicides Induce a Pathogen Survival Response in Community-Associated Methicillin-Resistant Staphylococcus aureus. J. Immunol. 180: 500-509 [Abstract] [Full Text]  
• James, L, Gorwitz, R J, Jones, R C, Watson, J T, Hageman, J C, Jernigan, D B, Lord, Y, Caballes, N, Cortes, C, Golash, R G, Price, J S, Gerber, S I (2008). Methicillin-resistant Staphylococcus aureus infections among healthy full-term newborns. Arch. Dis. Child. Fetal Neonatal Ed. 93: F40-F44 [Abstract] [Full Text]  
• Baker, C. J. (2007). Large CA-MRSA disease burden mandates prompt diagnosis, appropriate management. AAP News 28: 1-9 [Full Text]  
• Witte, W., Strommenger, B., Cuny, C., Heuck, D., Nuebel, U. (2007). Methicillin-resistant Staphylococcus aureus containing the Panton-Valentine leucocidin gene in Germany in 2005 and 2006. J Antimicrob Chemother 60: 1258-1263 [Abstract] [Full Text]  
• Park, C., Lee, D.-G., Kim, S. W., Choi, S.-M., Park, S. H., Chun, H.-S., Choi, J.-H., Yoo, J.-H., Shin, W. S., Kang, J. H., Kim, J. H., Lee, S. Y., Kim, S. M., Pyun, B. Y. (2007). Predominance of Community-Associated Methicillin-Resistant Staphylococcus aureus Strains Carrying Staphylococcal Chromosome Cassette mec Type IVA in South Korea. J. Clin. Microbiol. 45: 4021-4026 [Abstract] [Full Text]  
• Gupta, K., MacIntyre, A., Vanasse, G., Dembry, L.-M. (2007). Trends in Prescribing -Lactam Antibiotics for Treatment of Community-Associated Methicillin-Resistant Staphylococcus aureus Infections. J. Clin. Microbiol. 45: 3930-3934 [Abstract] [Full Text]  
• Kim, E. S., Song, J. S., Lee, H. J., Choe, P. G., Park, K. H., Cho, J. H., Park, W. B., Kim, S.-H., Bang, J.-H., Kim, D.-M., Park, K. U., Shin, S., Lee, M. S., Choi, H. J., Kim, N. J., Kim, E.-C., Oh, M.-d., Kim, H. B., Choe, K. W. (2007). A survey of community-associated methicillin-resistant Staphylococcus aureus in Korea. J Antimicrob Chemother 60: 1108-1114 [Abstract] [Full Text]  
• Simor, A. E., Stuart, T. L., Louie, L., Watt, C., Ofner-Agostini, M., Gravel, D., Mulvey, M., Loeb, M., McGeer, A., Bryce, E., Matlow, A., and the Canadian Nosocomial Infection Surveillance, (2007). Mupirocin-Resistant, Methicillin-Resistant Staphylococcus aureus Strains in Canadian Hospitals. Antimicrob. Agents Chemother. 51: 3880-3886 [Abstract] [Full Text]  
• Rajendran, P. M., Young, D., Maurer, T., Chambers, H., Perdreau-Remington, F., Ro, P., Harris, H. (2007). Randomized, Double-Blind, Placebo-Controlled Trial of Cephalexin for Treatment of Uncomplicated Skin Abscesses in a Population at Risk for Community-Acquired Methicillin-Resistant Staphylococcus aureus Infection. Antimicrob. Agents Chemother. 51: 4044-4048 [Abstract] [Full Text]  
• Olszewski, M. A., Falkowski, N. R., Surana, R., Sonstein, J., Hartman, A., Moore, B. B., Huffnagle, G. B., Toews, G. B. (2007). Effect of Laparotomy on Clearance and Cytokine Induction in Staphylococcus aureus infected Lungs. Am. J. Respir. Crit. Care Med. 176: 921-929 [Abstract] [Full Text]  
• Klevens, R. M., Morrison, M. A., Nadle, J., Petit, S., Gershman, K., Ray, S., Harrison, L. H., Lynfield, R., Dumyati, G., Townes, J. M., Craig, A. S., Zell, E. R., Fosheim, G. E., McDougal, L. K., Carey, R. B., Fridkin, S. K., for the Active Bacterial Core surveillance (ABCs), (2007). Invasive Methicillin-Resistant Staphylococcus aureus Infections in the United States. JAMA 298: 1763-1771 [Abstract] [Full Text]  
• Bancroft, E. A. (2007). Antimicrobial Resistance: It's Not Just for Hospitals. JAMA 298: 1803-1804 [Full Text]  
• Korownyk, C., Allan, G. M. (2007). Evidence-based approach to abscess management. cfp 53: 1680-1684 [Abstract] [Full Text]  
• Ellis, M. W., Griffith, M. E., Dooley, D. P., McLean, J. C., Jorgensen, J. H., Patterson, J. E., Davis, K. A., Hawley, J. S., Regules, J. A., Rivard, R. G., Gray, P. J., Ceremuga, J. M., DeJoseph, M. A., Hospenthal, D. R. (2007). Targeted Intranasal Mupirocin To Prevent Colonization and Infection by Community-Associated Methicillin-Resistant Staphylococcus aureus Strains in Soldiers: a Cluster Randomized Controlled Trial. Antimicrob. Agents Chemother. 51: 3591-3598 [Abstract] [Full Text]  
• Ruhe, J. J., Menon, A. (2007). Tetracyclines as an Oral Treatment Option for Patients with Community Onset Skin and Soft Tissue Infections Caused by Methicillin-Resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 51: 3298-3303 [Abstract] [Full Text]  
• Schlievert, P. M. (2007). Chitosan Malate Inhibits Growth and Exotoxin Production of Toxic Shock Syndrome-Inducing Staphylococcus aureus Strains and Group A Streptococci. Antimicrob. Agents Chemother. 51: 3056-3062 [Abstract] [Full Text]  
• Jones, R. N., Nilius, A. M., Akinlade, B. K., Deshpande, L. M., Notario, G. F. (2007). Molecular Characterization of Staphylococcus aureus Isolates from a 2005 Clinical Trial of Uncomplicated Skin and Skin Structure Infections. Antimicrob. Agents Chemother. 51: 3381-3384 [Abstract] [Full Text]  
• van Hal, S. J., Stark, D., Lockwood, B., Marriott, D., Harkness, J. (2007). Methicillin-Resistant Staphylococcus aureus (MRSA) Detection: Comparison of Two Molecular Methods (IDI-MRSA PCR Assay and GenoType MRSA Direct PCR Assay) with Three Selective MRSA Agars (MRSA ID, MRSASelect, and CHROMagar MRSA) for Use with Infection-Control Swabs. J. Clin. Microbiol. 45: 2486-2490 [Abstract] [Full Text]  
• Daum, R. S. (2007). Skin and Soft-Tissue Infections Caused by Methicillin-Resistant Staphylococcus aureus. NEJM 357: 380-390 [Full Text]  
• Lodise, T. P. Jr., Pypstra, R., Kahn, J. B., Murthy, B. P., Kimko, H. C., Bush, K., Noel, G. J., Drusano, G. L. (2007). Probability of Target Attainment for Ceftobiprole as Derived from a Population Pharmacokinetic Analysis of 150 Subjects. Antimicrob. Agents Chemother. 51: 2378-2387 [Abstract] [Full Text]  
• Popovich, K., Hota, B., Rice, T., Aroutcheva, A., Weinstein, R. A. (2007). Phenotypic Prediction Rule for Community-Associated Methicillin-Resistant Staphylococcus aureus. J. Clin. Microbiol. 45: 2293-2295 [Abstract] [Full Text]  
• Davis, S. L., Perri, M. B., Donabedian, S. M., Manierski, C., Singh, A., Vager, D., Haque, N. Z., Speirs, K., Muder, R. R., Robinson-Dunn, B., Hayden, M. K., Zervos, M. J. (2007). Epidemiology and Outcomes of Community-Associated Methicillin-Resistant Staphylococcus aureus Infection. J. Clin. Microbiol. 45: 1705-1711 [Abstract] [Full Text]  
• Bhattacharya, D., Carleton, H., Tsai, C. J., Baron, E. J., Perdreau-Remington, F. (2007). Differences in Clinical and Molecular Characteristics of Skin and Soft Tissue Methicillin-Resistant Staphylococcus aureus Isolates between Two Hospitals in Northern California. J. Clin. Microbiol. 45: 1798-1803 [Abstract] [Full Text]  
• Hota, B., Ellenbogen, C., Hayden, M. K., Aroutcheva, A., Rice, T. W., Weinstein, R. A. (2007). Community-Associated Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections at a Public Hospital: Do Public Housing and Incarceration Amplify Transmission?. Arch Intern Med 167: 1026-1033 [Abstract] [Full Text]  
• (2007). Severe Methicillin-Resistant Staphylococcus aureus Community-Acquired Pneumonia Associated With Influenza--Louisiana and Georgia, December 2006-January 2007. JAMA 297: 2070-2072 [Full Text]  
• Shastry, L., Rahimian, J., Lascher, S. (2007). Community-Associated Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections in Men Who Have Sex With Men in New York City. Arch Intern Med 167: 854-857 [Full Text]  
• Szumowski, J. D., Cohen, D. E., Kanaya, F., Mayer, K. H. (2007). Treatment and Outcomes of Infections by Methicillin-Resistant Staphylococcus aureus at an Ambulatory Clinic. Antimicrob. Agents Chemother. 51: 423-428 [Abstract] [Full Text]  
• Weigel, L. M., Donlan, R. M., Shin, D. H., Jensen, B., Clark, N. C., McDougal, L. K., Zhu, W., Musser, K. A., Thompson, J., Kohlerschmidt, D., Dumas, N., Limberger, R. J., Patel, J. B. (2007). High-Level Vancomycin-Resistant Staphylococcus aureus Isolates Associated with a Polymicrobial Biofilm. Antimicrob. Agents Chemother. 51: 231-238 [Abstract] [Full Text]  
• Bonnstetter, K. K., Wolter, D. J., Tenover, F. C., McDougal, L. K., Goering, R. V. (2007). Rapid Multiplex PCR Assay for Identification of USA300 Community-Associated Methicillin-Resistant Staphylococcus aureus Isolates. J. Clin. Microbiol. 45: 141-146 [Abstract] [Full Text]  
• Phillips, S., MacDougall, C., Holdford, D. A (2007). Analysis of Empiric Antimicrobial Strategies for Cellulitis in the Era of Methicillin-Resistant Staphylococcus aureus. The Annals of Pharmacotherapy 41: 13-20 [Abstract] [Full Text]  
• Javaheri, M, Khurana, R N, O'Hearn, T M, Lai, M M, Sadun, A A (2007). Linezolid-induced optic neuropathy: a mitochondrial disorder?. Br. J. Ophthalmol. 91: 111-115 [Abstract] [Full Text]  
• Kilic, A., Li, H., Stratton, C. W., Tang, Y.-W. (2006). Antimicrobial Susceptibility Patterns and Staphylococcal Cassette Chromosome mec Types of, as Well as Panton-Valentine Leukocidin Occurrence among, Methicillin-Resistant Staphylococcus aureus Isolates from Children and Adults in Middle Tennessee. J. Clin. Microbiol. 44: 4436-4440 [Abstract] [Full Text]  
• Kollef, M. H. (2006). Time to get serious about infection prevention in the ICU.. Chest 130: 1293-1296 [Full Text]  
• Ossowski, K., Chun, R. H., Suskind, D., Baroody, F. M. (2006). Increased Isolation of Methicillin-Resistant Staphylococcus aureus in Pediatric Head and Neck Abscesses.. Arch Otolaryngol Head Neck Surg 132: 1176-1181 [Abstract] [Full Text]  
• Lorber, B. (2006). Update in infectious diseases.. ANN INTERN MED 145: 354-360 [Full Text]  
• Kaka, A. S., Rueda, A. M., Shelburne, S. A. III, Hulten, K., Hamill, R. J., Musher, D. M. (2006). Bactericidal activity of orally available agents against methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother 58: 680-683 [Abstract] [Full Text]  
• Paydar, K. Z., Hansen, S. L., Charlebois, E. D., Harris, H. W., Young, D. M. (2006). Inappropriate Antibiotic Use in Soft Tissue Infections. Arch Surg 141: 850-856 [Abstract] [Full Text]  
• Moran, G. J., Krishnadasan, A., Gorwitz, R. J., Fosheim, G. E., McDougal, L. K., Carey, R. B., Talan, D. A., the EMERGEncy ID Net Study Group, (2006). Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department.. NEJM 355: 666-674 [Abstract] [Full Text]  
• Weems, J. J. Jr., Steinberg, J. P., Filler, S., Baddley, J. W., Corey, G. R., Sampathkumar, P., Winston, L., John, J. F., Kubin, C. J., Talwani, R., Moore, T., Patti, J. M., Hetherington, S., Texter, M., Wenzel, E., Kelley, V. A., Fowler, V. G. Jr. (2006). Phase II, Randomized, Double-Blind, Multicenter Study Comparing the Safety and Pharmacokinetics of Tefibazumab to Placebo for Treatment of Staphylococcus aureus Bacteremia.. Antimicrob. Agents Chemother. 50: 2751-2755 [Abstract] [Full Text]  
• (2006). Methicillin-Resistant Staphylococcus aureus Skin Infections Among Tattoo Recipients--Ohio, Kentucky, and Vermont, 2004-2005. JAMA 296: 385-386 [Full Text]  
• Allen, U. D. (2006). Public health implications of MRSA in Canada. CMAJ 175: 161-161 [Full Text]  
• (2006). Community-Associated Methicillin-Resistant Staphylococcus aureus Infection Among Healthy Newborns--Chicago and Los Angeles County, 2004. JAMA 296: 36-38 [Full Text]  
• Knight, C. L., Fihn, S. D. (2006). Update in General Internal Medicine. ANN INTERN MED 145: 52-61 [Full Text]  
• Patel, M., Waites, K. B., Moser, S. A., Cloud, G. A., Hoesley, C. J. (2006). Prevalence of Inducible Clindamycin Resistance among Community- and Hospital-Associated Staphylococcus aureus Isolates.. J. Clin. Microbiol. 44: 2481-2484 [Abstract] [Full Text]  
• Forrest, G. N., Mehta, S., Weekes, E., Lincalis, D. P., Johnson, J. K., Venezia, R. A. (2006). Impact of rapid in situ hybridization testing on coagulase-negative staphylococci positive blood cultures. J Antimicrob Chemother 58: 154-158 [Abstract] [Full Text]  
• Yao, J., Zhong, J., Fang, Y., Geisinger, E., Novick, R. P., Lambowitz, A. M. (2006). Use of targetrons to disrupt essential and nonessential genes in Staphylococcus aureus reveals temperature sensitivity of Ll.LtrB group II intron splicing. RNA 12: 1271-1281 [Abstract] [Full Text]  
• Carroll, K. C., Borek, A. P., Burger, C., Glanz, B., Bhally, H., Henciak, S., Flayhart, D. C. (2006). Evaluation of the BD Phoenix Automated Microbiology System for Identification and Antimicrobial Susceptibility Testing of Staphylococci and Enterococci.. J. Clin. Microbiol. 44: 2072-2077 [Abstract] [Full Text]  
• Sabol, K. E, Echevarria, K. L, Lewis, J. S II (2006). Community-Associated Methicillin-Resistant Staphylococcus aureus: New Bug, Old Drugs. The Annals of Pharmacotherapy 40: 1125-1133 [Abstract] [Full Text]  
• Cheng, N.-C., Chang, S.-C., Kuo, Y.-S., Wang, J.-L., Tang, Y.-B. (2006). Necrotizing Fasciitis Caused by Methicillin-Resistant Staphylococcus aureus Resulting in Death. A Report of Three Cases. JBJS 88: 1107-1110 [Full Text]