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Previous Volume 353:1585-1590 October 13, 2005 Number 15 Next

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SUMMARY

We report on a patient with long-standing severe autonomic failure that affected his sympathetic and parasympathetic nervous systems. Antibodies against the ganglionic acetylcholine receptors were detected in the serum. Removal of the antibodies by means of plasma exchange resulted in a dramatic clinical improvement.

Source Information

From the Franz Volhard Clinical Research Center and the Max Delbrück Center for Molecular Medicine (C.S., A.L.B., J.T., K.H., C.L., R.K., F.C.L., J.J.); the Department of Neurology (A.L.), Medical University Charité (C.S., A.L.B., J.T., K.H., C.L., R.K., F.C.L., J.J.); and Helios Klinikum (T.B.) — all in Berlin; and the Department of Neurology, University of Texas Southwestern Medical Center, Dallas (S.V.).

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