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Volume 360:1981-1988 May 7, 2009 Number 19
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Vaccine Refusal, Mandatory Immunization, and the Risks of Vaccine-Preventable Diseases
Saad B. Omer, M.B., B.S., Ph.D., M.P.H., Daniel A. Salmon, Ph.D., M.P.H., Walter A. Orenstein, M.D., M. Patricia deHart, Sc.D., and Neal Halsey, M.D.

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ABSTRACT

Vaccines are among the most effective prevention tools available to clinicians. However, the success of an immunization program depends on high rates of acceptance and coverage. There is evidence of an increase in vaccine refusal in the United States and of geographic clustering of refusals that results in outbreaks. Children with exemptions from school immunization requirements (a measure of vaccine refusal) are at increased risk for measles and pertussis and can infect others who are too young to be vaccinated, cannot be vaccinated for medical reasons, or were vaccinated but did not have a sufficient immunologic response. Clinicians can play a crucial role in parental decision making. Health care providers are cited as the most frequent source of immunization information by parents, including parents of unvaccinated children. Although some clinicians have discontinued or have considered discontinuing their provider relationship with patients who refuse vaccines, the American Academy of Pediatrics Committee on Bioethics advises against this and recommends that clinicians address vaccine refusal by respectfully listening to parental concerns and discussing the risks of nonvaccination.


Source Information

From the Hubert Department of Global Health, Rollins School of Public Health (S.B.O.), and the Emory Vaccine Center (S.B.O., W.A.O.), Emory University, Atlanta; the Department of International Health (S.B.O., D.A.S., N.H.) and the Institute for Vaccine Safety (N.H.), Johns Hopkins Bloomberg School of Public Health, Baltimore; the National Vaccine Program Office, Department of Health and Human Services, Washington, DC (D.A.S.); and Maternal and Child Health Assessment, Washington State Department of Health, Olympia (M.P.D.).

Address reprint requests to Dr. Omer at the Hubert Department of Global Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd. NE, Atlanta, GA 30322, or at somer{at}emory.edu.

Full Text of this Article


Related Letters:

Vaccine Refusal and the Risks of Vaccine-Preventable Diseases
Gill D. G., Leask J., McIntyre P. B., Omer S. B., Sanders D. A., the Reducing Vaccine Hesitancy Team
Extract | Full Text | PDF  
N Engl J Med 2009; 361:723-724, Aug 13, 2009. Correspondence

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