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Editorial
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Volume 354:1413-1415 March 30, 2006 Number 13
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Serious Adverse Drug Effects — Seeing the Trees through the Forest
Jerry H. Gurwitz, M.D.

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The medical community and the public have been buffeted by a steady stream of news linking the use of widely prescribed medications with serious health risks. The latest in this barrage of unsettling reports is an article by Park-Wyllie et al. that appears elsewhere in this issue of the Journal1 regarding the association of the fluoroquinolone gatifloxacin with dysglycemia.

The authors describe the findings of two population-based, nested case–control studies involving outpatients 66 years of age or older who had received treatment with various broad-spectrum antibiotics. The first study demonstrated a substantial increase in the risk of emergency department treatment . . . [Full Text of this Article]


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From the Meyers Primary Care Institute, a joint endeavor of the University of Massachusetts Medical School, the Fallon Clinic Foundation, and the Fallon Community Health Plan — all in Worcester, Mass.

This article was published at www.nejm.org on March 1, 2006.


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