FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Volume 336:1401-1408 May 15, 1997 Number 20 Next

Abstract Full Text PDF Letters Add to Personal Archive Add to Citation Manager E-mail When Cited PubMed Citation

From the Division of Cancer Epidemiology and Genetics, National Cancer Institute (J.P.S., P.H., S.W., M.A.T.), and the Laboratory of Gene Transfer, National Human Genome Research Institute (J.P.S., S.M.B., M.M.T., L.C.B.), National Institutes of Health, Bethesda, Md.; Westat, Inc., Rockville, Md. (M.B.); and IMS, Inc., Silver Spring, Md. (M.M.).

Address reprint requests to Dr. Struewing at the Genetic Epidemiology Branch, Bldg. EPN, Rm. 439, 6130 Executive Blvd., MSC 7372, Bethesda, MD 20892-7372.

Full Text of this Article

Related Letters:

Risk of Breast Cancer in Carriers of BRCA Gene Mutations
Orlando R., Birkmeyer J. D., Welch H. G., Meijer W. J., van Lindert A. C.M., Grann V., Whittemore A. S., Schrag D., Weeks J. C.
Extract | Full Text  
N Engl J Med 1997; 337:787-789, Sep 11, 1997. Correspondence

This article has been cited by other articles:

• Allain, D. C. (2008). Genetic Counseling and Testing for Common Hereditary Breast Cancer Syndromes: A Paper from the 2007 William Beaumont Hospital Symposium on Molecular Pathology. J. Mol. Diagn. 10: 383-395 [Abstract] [Full Text]  
• Palma, M. D., Domchek, S. M., Stopfer, J., Erlichman, J., Siegfried, J. D., Tigges-Cardwell, J., Mason, B. A., Rebbeck, T. R., Nathanson, K. L. (2008). The Relative Contribution of Point Mutations and Genomic Rearrangements in BRCA1 and BRCA2 in High-Risk Breast Cancer Families. Cancer Res. 68: 7006-7014 [Abstract] [Full Text]  
• Ostrander, E. A., Udler, M. S. (2008). The Role of the BRCA2 Gene in Susceptibility to Prostate Cancer Revisited. Cancer Epidemiol. Biomarkers Prev. 17: 1843-1848 [Abstract] [Full Text]  
• Suijkerbuijk, K. P. M., Fackler, M. J., Sukumar, S., van Gils, C. H., van Laar, T., van der Wall, E., Vooijs, M., van Diest, P. J. (2008). Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer. Ann Oncol 0: mdn409v1-mdn409 [Abstract] [Full Text]  
• De Nicolo, A., Tancredi, M., Lombardi, G., Flemma, C. C., Barbuti, S., Di Cristofano, C., Sobhian, B., Bevilacqua, G., Drapkin, R., Caligo, M. A. (2008). A Novel Breast Cancer-Associated BRIP1 (FANCJ/BACH1) Germ-line Mutation Impairs Protein Stability and Function. Clin. Cancer Res. 14: 4672-4680 [Abstract] [Full Text]  
• Lynch, H. T., Ferrara, K., Barlogie, B., Coleman, E. A., Lynch, J. F., Weisenburger, D., Sanger, W., Watson, P., Nipper, H., Witt, V., Thome, S. (2008). Familial Myeloma. NEJM 359: 152-157 [Abstract] [Full Text]  
• Mor, P., Oberle, K. (2008). Ethical Issues Related To BRCA Gene Testing in Orthodox Jewish Women. Nurs Ethics 15: 512-522 [Abstract]  
• Byrd, L. M., Shenton, A., Maher, E. R., Woodward, E., Belk, R., Lim, C., Lalloo, F., Howell, A., Jayson, G. C., Evans, G. D. (2008). Better Life Expectancy in Women with BRCA2 Compared with BRCA1 Mutations Is Attributable to Lower Frequency and Later Onset of Ovarian Cancer. Cancer Epidemiol. Biomarkers Prev. 17: 1535-1542 [Abstract] [Full Text]  
• Wang, Y., Clark, L. N., Louis, E. D., Mejia-Santana, H., Harris, J., Cote, L. J., Waters, C., Andrews, H., Ford, B., Frucht, S., Fahn, S., Ottman, R., Rabinowitz, D., Marder, K. (2008). Risk of Parkinson Disease in Carriers of Parkin Mutations: Estimation Using the Kin-Cohort Method. Arch Neurol 65: 467-474 [Abstract] [Full Text]  
• Niewoehner, C. B, Schorer, A. E (2008). Gynaecomastia and breast cancer in men. BMJ 336: 709-713 [Full Text]  
• Kauff, N. D., Domchek, S. M., Friebel, T. M., Robson, M. E., Lee, J., Garber, J. E., Isaacs, C., Evans, D. G., Lynch, H., Eeles, R. A., Neuhausen, S. L., Daly, M. B., Matloff, E., Blum, J. L., Sabbatini, P., Barakat, R. R., Hudis, C., Norton, L., Offit, K., Rebbeck, T. R. (2008). Risk-Reducing Salpingo-Oophorectomy for the Prevention of BRCA1- and BRCA2-Associated Breast and Gynecologic Cancer: A Multicenter, Prospective Study. JCO 26: 1331-1337 [Abstract] [Full Text]  
• Chan-Smutko, G., Patel, D., Shannon, K. M., Ryan, P. D. (2008). Professional Challenges in Cancer Genetic Testing: Who Is the Patient?. The Oncologist 13: 232-238 [Abstract] [Full Text]  
• Begg, C. B., Haile, R. W., Borg, A., Malone, K. E., Concannon, P., Thomas, D. C., Langholz, B., Bernstein, L., Olsen, J. H., Lynch, C. F., Anton-Culver, H., Capanu, M., Liang, X., Hummer, A. J., Sima, C., Bernstein, J. L. (2008). Variation of Breast Cancer Risk Among BRCA1/2 Carriers. JAMA 299: 194-201 [Abstract] [Full Text]  
• Chetrit, A., Hirsh-Yechezkel, G., Ben-David, Y., Lubin, F., Friedman, E., Sadetzki, S. (2008). Effect of BRCA1/2 Mutations on Long-Term Survival of Patients With Invasive Ovarian Cancer: The National Israeli Study of Ovarian Cancer. JCO 26: 20-25 [Abstract] [Full Text]  
• Heemskerk-Gerritsen, B. A. M., Brekelmans, C. T. M., Menke-Pluymers, M. B. E., van Geel, A. N., Tilanus-Linthorst, M. M. A., Bartels, C. C. M., Tan, M., Meijers-Heijboer, H. E. J., Klijn, J. G. M., Seynaeve, C. (2007). Prophylactic Mastectomy in BRCA1/2 Mutation Carriers and Women at Risk of Hereditary Breast Cancer: Long-Term Experiences at the Rotterdam Family Cancer Clinic. Ann. Surg. Oncol. 14: 3335-3344 [Abstract] [Full Text]  
• Jordan, V. C. (2007). Estrogen Receptors in BRCA1-Mutant Breast Cancer: Now You See Them, Now You Don't. JNCI J Natl Cancer Inst 99: 1655-1657 [Full Text]  
• Parmigiani, G., Chen, S., Iversen, E. S. Jr, Friebel, T. M., Finkelstein, D. M., Anton-Culver, H., Ziogas, A., Weber, B. L., Eisen, A., Malone, K. E., Daling, J. R., Hsu, L., Ostrander, E. A., Peterson, L. E., Schildkraut, J. M., Isaacs, C., Corio, C., Leondaridis, L., Tomlinson, G., Amos, C. I., Strong, L. C., Berry, D. A., Weitzel, J. N., Sand, S., Dutson, D., Kerber, R., Peshkin, B. N., Euhus, D. M. (2007). Validity of Models for Predicting BRCA1 and BRCA2 Mutations. ANN INTERN MED 147: 441-450 [Abstract] [Full Text]  
• Underkuffler, L. S. (2007). Human Genetics Studies: The Case for Group Rights. J Law Med Ethics 35: 383-395  
• Callahan, M. J., Crum, C. P., Medeiros, F., Kindelberger, D. W., Elvin, J. A., Garber, J. E., Feltmate, C. M., Berkowitz, R. S., Muto, M. G. (2007). Primary Fallopian Tube Malignancies in BRCA-Positive Women Undergoing Surgery for Ovarian Cancer Risk Reduction. JCO 25: 3985-3990 [Abstract] [Full Text]  
• Bradbury, A. R., Dignam, J. J., Ibe, C. N., Auh, S. L., Hlubocky, F. J., Cummings, S. A., White, M., Olopade, O. I., Daugherty, C. K. (2007). How Often Do BRCA Mutation Carriers Tell Their Young Children of the Family's Risk for Cancer? A Study of Parental Disclosure of BRCA Mutations to Minors and Young Adults. JCO 25: 3705-3711 [Abstract] [Full Text]  
• Smith, K. L., Adank, M., Kauff, N., Lafaro, K., Boyd, J., Lee, J. B., Hudis, C., Offit, K., Robson, M. (2007). BRCA Mutations in Women with Ductal Carcinoma In situ. Clin. Cancer Res. 13: 4306-4310 [Abstract] [Full Text]  
• Rennert, G., Bisland-Naggan, S., Barnett-Griness, O., Bar-Joseph, N., Zhang, S., Rennert, H. S., Narod, S. A. (2007). Clinical Outcomes of Breast Cancer in Carriers of BRCA1 and BRCA2 Mutations. NEJM 357: 115-123 [Abstract] [Full Text]  
• Kauff, N. D., Barakat, R. R. (2007). Risk-Reducing Salpingo-Oophorectomy in Patients With Germline Mutations in BRCA1 or BRCA2. JCO 25: 2921-2927 [Abstract] [Full Text]  
• Karlan, B. Y., Berchuck, A., Mutch, D. (2007). The Role of Genetic Testing for Cancer Susceptibility in Gynecologic Practice. Obstet Gynecol 110: 155-167 [Abstract] [Full Text]  
• Douglas, J. A., Levin, A. M., Zuhlke, K. A., Ray, A. M., Johnson, G. R., Lange, E. M., Wood, D. P., Cooney, K. A. (2007). Common Variation in the BRCA1 Gene and Prostate Cancer Risk. Cancer Epidemiol. Biomarkers Prev. 16: 1510-1516 [Abstract] [Full Text]  
• Kadouri, L., Hubert, A., Rotenberg, Y., Hamburger, T., Sagi, M., Nechushtan, C., Abeliovich, D., Peretz, T. (2007). Cancer risks in carriers of the BRCA1/2 Ashkenazi founder mutations. J. Med. Genet. 44: 467-471 [Abstract] [Full Text]  
• Weitzel, J. N., Lagos, V. I., Cullinane, C. A., Gambol, P. J., Culver, J. O., Blazer, K. R., Palomares, M. R., Lowstuter, K. J., MacDonald, D. J. (2007). Limited Family Structure and BRCA Gene Mutation Status in Single Cases of Breast Cancer. JAMA 297: 2587-2595 [Abstract] [Full Text]  
• Tryggvadottir, L., Vidarsdottir, L., Thorgeirsson, T., Jonasson, J. G., Olafsdottir, E. J., Olafsdottir, G. H., Rafnar, T., Thorlacius, S., Jonsson, E., Eyfjord, J. E., Tulinius, H. (2007). Prostate Cancer Progression and Survival in BRCA2 Mutation Carriers. JNCI J Natl Cancer Inst 99: 929-935 [Abstract] [Full Text]  
• Wang, Y., Clark, L. N., Marder, K., Rabinowitz, D. (2007). Nonparametric estimation of age-at-onset distributions from censored kin-cohort data. Biometrika 94: 403-403 [Abstract] [Full Text]  
• Machado, P. M., Brandao, R. D., Cavaco, B. M., Eugenio, J., Bento, S., Nave, M., Rodrigues, P., Fernandes, A., Vaz, F. (2007). Screening for a BRCA2 Rearrangement in High-Risk Breast/Ovarian Cancer Families: Evidence for a Founder Effect and Analysis of the Associated Phenotypes. JCO 25: 2027-2034 [Abstract] [Full Text]  
• Greer, J. B, Whitcomb, D. C (2007). Role of BRCA1 and BRCA2 mutations in pancreatic cancer. Gut 56: 601-605 [Abstract] [Full Text]  
• Chen, S., Parmigiani, G. (2007). Meta-Analysis of BRCA1 and BRCA2 Penetrance. JCO 25: 1329-1333 [Abstract] [Full Text]  
• Saslow, D., Boetes, C., Burke, W., Harms, S., Leach, M. O., Lehman, C. D., Morris, E., Pisano, E., Schnall, M., Sener, S., Smith, R. A., Warner, E., Yaffe, M., Andrews, K. S., Russell, C. A., for the American Cancer Society Breast Cancer Advi, (2007). American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography. CA Cancer J Clin 57: 75-89 [Abstract] [Full Text]  
• Jakubowska, A., Gronwald, J., Menkiszak, J., Gorski, B., Huzarski, T., Byrski, T., Edler, L., Lubinski, J., Scott, R. J., Hamann, U. (2007). The RAD51 135 G>C Polymorphism Modifies Breast Cancer and Ovarian Cancer Risk in Polish BRCA1 Mutation Carriers. Cancer Epidemiol. Biomarkers Prev. 16: 270-275 [Abstract] [Full Text]  
• Soran, A., Falk, J., Bonaventura, M., Keenan, D., Ahrendt, G., Johnson, R. (2007). Is Routine Sentinel Lymph Node Biopsy Indicated in Women Undergoing Contralateral Prophylactic Mastectomy? Magee-Womens Hospital Experience. Ann. Surg. Oncol. 14: 646-651 [Abstract] [Full Text]  
• Smith, A, Moran, A, Boyd, M C, Bulman, M, Shenton, A, Smith, L, Iddenden, R, Woodward, E R, Lalloo, F, Maher, E R, Evans, D G R (2007). Phenocopies in BRCA1 and BRCA2 families: evidence for modifier genes and implications for screening. J. Med. Genet. 44: 10-15 [Abstract] [Full Text]  
• Offit, K. (2006). BRCA Mutation Frequency and Penetrance: New Data, Old Debate. JNCI J Natl Cancer Inst 98: 1675-1677 [Full Text]  
• Risch, H. A., McLaughlin, J. R., Cole, D. E. C., Rosen, B., Bradley, L., Fan, I., Tang, J., Li, S., Zhang, S., Shaw, P. A., Narod, S. A. (2006). Population BRCA1 and BRCA2 Mutation Frequencies and Cancer Penetrances: A Kin-Cohort Study in Ontario, Canada. JNCI J Natl Cancer Inst 98: 1694-1706 [Abstract] [Full Text]  
• Clark, L. N., Wang, Y., Karlins, E., Saito, L., Mejia-Santana, H., Harris, J., Louis, E. D., Cote, L. J., Andrews, H., Fahn, S., Waters, C., Ford, B., Frucht, S., Ottman, R., Marder, K. (2006). Frequency of LRRK2 mutations in early- and late-onset Parkinson disease. Neurology 67: 1786-1791 [Abstract] [Full Text]  
• Brandt-Rauf, S. I., Raveis, V. H., Drummond, N. F., Conte, J. A., Rothman, S. M. (2006). Ashkenazi Jews and Breast Cancer: The Consequences of Linking Ethnic Identity to Genetic Disease. Am. J. Public Health 96: 1979-1988 [Abstract] [Full Text]  
• Guillem, J. G., Wood, W. C., Moley, J. F., Berchuck, A., Karlan, B. Y., Mutch, D. G., Gagel, R. F., Weitzel, J., Morrow, M., Weber, B. L., Giardiello, F., Rodriguez-Bigas, M. A., Church, J., Gruber, S., Offit, K. (2006). ASCO/SSO Review of Current Role of Risk-Reducing Surgery in Common Hereditary Cancer Syndromes. JCO 24: 4642-4660 [Abstract] [Full Text]  
• Guillem, J. G., Wood, W. C., Moley, J. F., Berchuck, A., Karlan, B. Y., Mutch, D. G., Gagel, R. F., Weitzel, J., Morrow, M., Weber, B. L., Giardiello, F., Rodriguez-Bigas, M. A., Church, J., Gruber, S., Offit, K. (2006). ASCO/SSO Review of Current Role of Risk-Reducing Surgery in Common Hereditary Cancer Syndromes. Ann. Surg. Oncol. 13: 1296-1321 [Abstract] [Full Text]  
• Schmeler, K. M., Sun, C. C., Bodurka, D. C., White, K. G., Soliman, P. T., Uyei, A. R., Erlichman, J. L., Arun, B. K., Daniels, M. S., Rimes, S. A., Peterson, S. K., Slomovitz, B. M., Milam, M. R., Gershenson, D. M., Lu, K. H. (2006). Prophylactic Bilateral Salpingo-Oophorectomy Compared With Surveillance in Women With BRCA Mutations.. Obstet Gynecol 108: 515-520 [Abstract] [Full Text]  
• Malone, K. E., Daling, J. R., Doody, D. R., Hsu, L., Bernstein, L., Coates, R. J., Marchbanks, P. A., Simon, M. S., McDonald, J. A., Norman, S. A., Strom, B. L., Burkman, R. T., Ursin, G., Deapen, D., Weiss, L. K., Folger, S., Madeoy, J. J., Friedrichsen, D. M., Suter, N. M., Humphrey, M. C., Spirtas, R., Ostrander, E. A. (2006). Prevalence and Predictors of BRCA1 and BRCA2 Mutations in a Population-Based Study of Breast Cancer in White and Black American Women Ages 35 to 64 Years. Cancer Res. 66: 8297-8308 [Abstract] [Full Text]  
• Finch, A., Beiner, M., Lubinski, J., Lynch, H. T., Moller, P., Rosen, B., Murphy, J., Ghadirian, P., Friedman, E., Foulkes, W. D., Kim-Sing, C., Wagner, T., Tung, N., Couch, F., Stoppa-Lyonnet, D., Ainsworth, P., Daly, M., Pasini, B., Gershoni-Baruch, R., Eng, C., Olopade, O. I., McLennan, J., Karlan, B., Weitzel, J., Sun, P., Narod, S. A., for the Hereditary Ovarian Cancer Clinical Study G, (2006). Salpingo-oophorectomy and the Risk of Ovarian, Fallopian Tube, and Peritoneal Cancers in Women With a BRCA1 or BRCA2 Mutation. JAMA 296: 185-192 [Abstract] [Full Text]  
• Chen, S., Iversen, E. S. Jr, Parmigiani, G. (2006). In Reply. JCO 24: 3313-3314 [Full Text]  
• Cohen, P. E., Pollack, S. E., Pollard, J. W. (2006). Genetic Analysis of Chromosome Pairing, Recombination, and Cell Cycle Control during First Meiotic Prophase in Mammals. Endocr. Rev. 27: 398-426 [Abstract] [Full Text]  
• Pierce, L. J., Levin, A. M., Rebbeck, T. R., Ben-David, M. A., Friedman, E., Solin, L. J., Harris, E. E., Gaffney, D. K., Haffty, B. G., Dawson, L. A., Narod, S. A., Olivotto, I. A., Eisen, A., Whelan, T. J., Olopade, O. I., Isaacs, C., Merajver, S. D., Wong, J. S., Garber, J. E., Weber, B. L. (2006). Ten-Year Multi-Institutional Results of Breast-Conserving Surgery and Radiotherapy in BRCA1/2-Associated Stage I/II Breast Cancer. JCO 24: 2437-2443 [Abstract] [Full Text]  
• Yarden, R. I., Papa, M. Z. (2006). BRCA1 at the crossroad of multiple cellular pathways: approaches for therapeutic interventions.. Molecular Cancer Therapeutics 5: 1396-1404 [Abstract] [Full Text]  
• Plevritis, S. K., Kurian, A. W., Sigal, B. M., Daniel, B. L., Ikeda, D. M., Stockdale, F. E., Garber, A. M. (2006). Cost-effectiveness of screening BRCA1/2 mutation carriers with breast magnetic resonance imaging.. JAMA 295: 2374-2384 [Abstract] [Full Text]  
• Kang, H. J., Kim, H. J., Rih, J.-K., Mattson, T. L., Kim, K. W., Cho, C.-H., Isaacs, J. S., Bae, I. (2006). BRCA1 Plays a Role in the Hypoxic Response by Regulating HIF-1{alpha} Stability and by Modulating Vascular Endothelial Growth Factor Expression. J. Biol. Chem. 281: 13047-13056 [Abstract] [Full Text]  
• Hinney, A., Bettecken, T., Tarnow, P., Brumm, H., Reichwald, K., Lichtner, P., Scherag, A., Nguyen, T. T., Schlumberger, P., Rief, W., Vollmert, C., Illig, T., Wichmann, H-E., Schafer, H., Platzer, M., Biebermann, H., Meitinger, T., Hebebrand, J. (2006). Prevalence, Spectrum, and Functional Characterization of Melanocortin-4 Receptor Gene Mutations in a Representative Population-Based Sample and Obese Adults from Germany. J. Clin. Endocrinol. Metab. 91: 1761-1769 [Abstract] [Full Text]  
• Loud, J. T., Weissman, N. E., Peters, J. A., Giusti, R. M., Wilfond, B. S., Burke, W., Greene, M. H. (2006). Deliberate Deceit of Family Members: A Challenge to Providers of Clinical Genetics Services. JCO 24: 1643-1646 [Full Text]  
• Deng, C.-X. (2006). BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution. Nucleic Acids Res 34: 1416-1426 [Abstract] [Full Text]  
• Ryan, P. D., Harisinghani, M., Lerwill, M. F., Kaufman, D. S. (2006). Case records of the Massachusetts General Hospital. Case 6-2006. A 71-year-old woman with urinary incontinence and a mass in the bladder.. NEJM 354: 850-856 [Full Text]  
• Chen, S., Iversen, E. S., Friebel, T., Finkelstein, D., Weber, B. L., Eisen, A., Peterson, L. E., Schildkraut, J. M., Isaacs, C., Peshkin, B. N., Corio, C., Leondaridis, L., Tomlinson, G., Dutson, D., Kerber, R., Amos, C. I., Strong, L. C., Berry, D. A., Euhus, D. M., Parmigiani, G. (2006). Characterization of BRCA1 and BRCA2 Mutations in a Large United States Sample. JCO 24: 863-871 [Abstract] [Full Text]  
• Tryggvadottir, L., Sigvaldason, H., Olafsdottir, G. H., Jonasson, J. G., Jonsson, T., Tulinius, H., Eyfjord, J. E. (2006). Population-Based Study of Changing Breast Cancer Risk in Icelandic BRCA2 Mutation Carriers, 1920-2000. JNCI J Natl Cancer Inst 98: 116-122 [Abstract] [Full Text]  
• Ma, Y., Katiyar, P., Jones, L. P., Fan, S., Zhang, Y., Furth, P. A., Rosen, E. M. (2006). The Breast Cancer Susceptibility Gene BRCA1 Regulates Progesterone Receptor Signaling in Mammary Epithelial Cells. Mol. Endocrinol. 20: 14-34 [Abstract] [Full Text]  
• Kramer, J. L., Velazquez, I. A., Chen, B. E., Rosenberg, P. S., Struewing, J. P., Greene, M. H. (2005). Prophylactic Oophorectomy Reduces Breast Cancer Penetrance During Prospective, Long-Term Follow-Up of BRCA1 Mutation Carriers. JCO 23: 8629-8635 [Abstract] [Full Text]  
• Gogas, H., Markopoulos, C., Blamey, R. (2005). Should women be advised to take prophylactic endocrine treatment outside of a clinical trial setting?. Ann Oncol 16: 1861-1866 [Abstract] [Full Text]  
• Rebbeck, T. R., Friebel, T., Wagner, T., Lynch, H. T., Garber, J. E., Daly, M. B., Isaacs, C., Olopade, O. I., Neuhausen, S. L., van 't Veer, L., Eeles, R., Evans, D. G., Tomlinson, G., Matloff, E., Narod, S. A., Eisen, A., Domchek, S., Armstrong, K., Weber, B. L. (2005). Effect of Short-Term Hormone Replacement Therapy on Breast Cancer Risk Reduction After Bilateral Prophylactic Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group. JCO 23: 7804-7810 [Abstract] [Full Text]  
• Begg, C. B., Orlow, I., Hummer, A. J., Armstrong, B. K., Kricker, A., Marrett, L. D., Millikan, R. C., Gruber, S. B., Anton-Culver, H., Zanetti, R., Gallagher, R. P., Dwyer, T., Rebbeck, T. R., Mitra, N., Busam, K., From, L., Berwick, M., for the Genes Environment and Melanoma (GEM) Study, (2005). Lifetime Risk of Melanoma in CDKN2A Mutation Carriers in a Population-Based Sample. JNCI J Natl Cancer Inst 97: 1507-1515 [Abstract] [Full Text]  
• Miller, S. M., Roussi, P., Daly, M. B., Buzaglo, J. S., Sherman, K., Godwin, A. K., Balshem, A., Atchison, M. E. (2005). Enhanced Counseling for Women Undergoing BRCA1/2 Testing: Impact on Subsequent Decision Making About Risk Reduction Behaviors. Health Educ Behav 32: 654-667 [Abstract]  
• Zhang, Y., Fan, S., Meng, Q., Ma, Y., Katiyar, P., Schlegel, R., Rosen, E. M. (2005). BRCA1 Interaction with Human Papillomavirus Oncoproteins. J. Biol. Chem. 280: 33165-33177 [Abstract] [Full Text]  
• U.S. Preventive Services Task Force*, (2005). Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Recommendation Statement. ANN INTERN MED 143: 355-361 [Abstract] [Full Text]  
• Nelson, H. D., Huffman, L. H., Fu, R., Harris, E. L. (2005). Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Systematic Evidence Review for the U.S. Preventive Services Task Force. ANN INTERN MED 143: 362-379 [Abstract] [Full Text]  
• Rosen, E M, Fan, S, Isaacs, C (2005). BRCA1 in hormonal carcinogenesis: basic and clinical research. Endocr Relat Cancer 12: 533-548 [Abstract] [Full Text]  
• Hamann, H. A., Somers, T. J., Smith, A. W., Inslicht, S. S., Baum, A. (2005). Posttraumatic Stress Associated With Cancer History and BRCA1/2 Genetic Testing. Psychosom. Med. 67: 766-772 [Abstract] [Full Text]  
• van Asperen, C J, Brohet, R M, Meijers-Heijboer, E J, Hoogerbrugge, N, Verhoef, S, Vasen, H F A, Ausems, M G E M, Menko, F H, Gomez Garcia, E B, Klijn, J G M, Hogervorst, F B L, van Houwelingen, J C, van't Veer, L J, Rookus, M A, van Leeuwen, F E, on behalf of the Netherlands Collaborative Group o, (2005). Cancer risks in BRCA2 families: estimates for sites other than breast and ovary. J. Med. Genet. 42: 711-719 [Abstract] [Full Text]  
• Freedman, M. L., Penney, K. L., Stram, D. O., Riley, S., McKean-Cowdin, R., Le Marchand, L., Altshuler, D., Haiman, C. A. (2005). A Haplotype-Based Case-Control Study of BRCA1 and Sporadic Breast Cancer Risk. Cancer Res. 65: 7516-7522 [Abstract] [Full Text]  
• Wang, C., Fan, S., Li, Z., Fu, M., Rao, M., Ma, Y., Lisanti, M. P., Albanese, C., Katzenellenbogen, B. S., Kushner, P. J., Weber, B., Rosen, E. M., Pestell, R. G. (2005). Cyclin D1 Antagonizes BRCA1 Repression of Estrogen Receptor {alpha} Activity. Cancer Res. 65: 6557-6567 [Abstract] [Full Text]  
• Weitzel, J. N., Lagos, V., Blazer, K. R., Nelson, R., Ricker, C., Herzog, J., McGuire, C., Neuhausen, S. (2005). Prevalence of BRCA Mutations and Founder Effect in High-Risk Hispanic Families. Cancer Epidemiol. Biomarkers Prev. 14: 1666-1671 [Abstract] [Full Text]  
• Antoniou, A C, Pharoah, P D P, Narod, S, Risch, H A, Eyfjord, J E, Hopper, J L, Olsson, H, Johannsson, O, Borg, A, Pasini, B, Radice, P, Manoukian, S, Eccles, D M, Tang, N, Olah, E, Anton-Culver, H, Warner, E, Lubinski, J, Gronwald, J, Gorski, B, Tulinius, H, Thorlacius, S, Eerola, H, Nevanlinna, H, Syrjakoski, K, Kallioniemi, O-P, Thompson, D, Evans, C, Peto, J, Lalloo, F, Evans, D G, Easton, D F (2005). Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies. J. Med. Genet. 42: 602-603 [Abstract] [Full Text]  
• Cook, J. D., Davis, B. J., Cai, S.-L., Barrett, J. C., Conti, C. J., Walker, C. L. (2005). Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance. Proc. Natl. Acad. Sci. USA 102: 8644-8649 [Abstract] [Full Text]  
• Weitzel, J. N., Robson, M., Pasini, B., Manoukian, S., Stoppa-Lyonnet, D., Lynch, H. T., McLennan, J., Foulkes, W. D., Wagner, T., Tung, N., Ghadirian, P., Olopade, O., Isaacs, C., Kim-Sing, C., Moller, P., Neuhausen, S. L., Metcalfe, K., Sun, P., Narod, S. A. (2005). A Comparison of Bilateral Breast Cancers in BRCA Carriers. Cancer Epidemiol. Biomarkers Prev. 14: 1534-1538 [Abstract] [Full Text]  
• Eberl, M. M., Sunga, A. Y., Farrell, C. D., Mahoney, M. C. (2005). Patients with a Family History of Cancer: Identification and Management. J Am Board Fam Med 18: 211-217 [Abstract] [Full Text]  
• Simeone, A.-M., Deng, C.-X., Kelloff, G. J., Steele, V. E., Johnson, M. M., Tari, A. M. (2005). N-(4-Hydroxyphenyl)retinamide is more potent than other phenylretinamides in inhibiting the growth of BRCA1-mutated breast cancer cells. Carcinogenesis 26: 1000-1007 [Abstract] [Full Text]  
• Schwartz, M. D., Lerman, C., Brogan, B., Peshkin, B. N., Isaacs, C., DeMarco, T., Hughes Halbert, C., Pennanen, M., Finch, C. (2005). Utilization of BRCA1/BRCA2 Mutation Testing in Newly Diagnosed Breast Cancer Patients. Cancer Epidemiol. Biomarkers Prev. 14: 1003-1007 [Abstract] [Full Text]  
• Patterson, A. R., Robinson, L. D., Naftalis, E. Z., Haley, B. B., Tomlinson, G. E. (2005). Custodianship of Genetic Information: Clinical Challenges and Professional Responsibility. JCO 23: 2100-2104 [Full Text]  
• Gurmankin, A. D., Domchek, S., Stopfer, J., Fels, C., Armstrong, K. (2005). Patients' Resistance to Risk Information in Genetic Counseling for BRCA1/2. Arch Intern Med 165: 523-529 [Abstract] [Full Text]  
• Narod, S. A., Offit, K. (2005). Prevention and Management of Hereditary Breast Cancer. JCO 23: 1656-1663 [Full Text]  
• Leegte, B, van der Hout, A H, Deffenbaugh, A M, Bakker, M K, Mulder, I M, ten Berge, A, Leenders, E P, Wesseling, J, de Hullu, J, Hoogerbrugge, N, Ligtenberg, M J L, Ardern-Jones, A, Bancroft, E, Salmon, A, Barwell, J, Eeles, R, Oosterwijk, J C (2005). Phenotypic expression of double heterozygosity for BRCA1 and BRCA2 germline mutations. J. Med. Genet. 42: e20-e20 [Full Text]  
• Khanna, C., Hunter, K. (2005). Modeling metastasis in vivo. Carcinogenesis 26: 513-523 [Abstract] [Full Text]  
• Lynch, H. T., Watson, P., Tarantolo, S., Wiernik, P. H., Quinn-Laquer, B., Isgur Bergsagel, K., Huiart, L., Olopade, O.I., Sobol, H., Sanger, W., Hogg, D., Weisenburger, D. (2005). Phenotypic Heterogeneity in Multiple Myeloma Families. JCO 23: 685-693 [Abstract] [Full Text]  
• Parthasarathy, S. (2005). Architectures of Genetic Medicine: Comparing Genetic Testing for Breast Cancer in the USA and the UK. Social Studies of Science 35: 5-40 [Abstract]  
• Bourret, P. (2005). BRCA Patients and Clinical Collectives: New Configurations of Action in Cancer Genetics Practices. Social Studies of Science 35: 41-68 [Abstract]  
• Wu, K., Hinson, S. R., Ohashi, A., Farrugia, D., Wendt, P., Tavtigian, S. V., Deffenbaugh, A., Goldgar, D., Couch, F. J. (2005). Functional Evaluation and Cancer Risk Assessment of BRCA2 Unclassified Variants. Cancer Res. 65: 417-426 [Abstract] [Full Text]  
• Cannistra, S. A. (2004). Cancer of the Ovary. NEJM 351: 2519-2529 [Full Text]  
• Whittemore, A. S., Gong, G., John, E. M., McGuire, V., Li, F. P., Ostrow, K. L., DiCioccio, R., Felberg, A., West, D. W. (2004). Prevalence of BRCA1 Mutation Carriers among U.S. Non-Hispanic Whites. Cancer Epidemiol. Biomarkers Prev. 13: 2078-2083 [Abstract] [Full Text]  
• Lorenzo Bermejo, J., Hemminki, K. (2004). Risk of cancer at sites other than the breast in Swedish families eligible for BRCA1 or BRCA2 mutation testing. Ann Oncol 15: 1834-1841 [Abstract] [Full Text]  
• Oloparde, O. I. (2004). Genetics in Clinical Cancer Care: A Promise Unfulfilled among Minority Populations. Cancer Epidemiol. Biomarkers Prev. 13: 1683-1686 [Full Text]  
• Arun, B. (2004). Ductal Lavage and Risk Assessment of Breast Cancer. The Oncologist 9: 599-605 [Abstract] [Full Text]  
• McGuire, V., Felberg, A., Mills, M., Ostrow, K. L., DiCioccio, R., John, E. M., West, D. W., Whittemore, A. S. (2004). Relation of Contraceptive and Reproductive History to Ovarian Cancer Risk in Carriers and Noncarriers of BRCA1 Gene Mutations. Am J Epidemiol 160: 613-618 [Abstract] [Full Text]  
• Dempfle, A, Hinney, A, Heinzel-Gutenbrunner, M, Raab, M, Geller, F, Gudermann, T, Schafer, H, Hebebrand, J (2004). Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index. J. Med. Genet. 41: 795-800 [Full Text]  
• Wacholder, S. (2004). Bias in Intervention Studies That Enroll Patients From High-Risk Clinics. JNCI J Natl Cancer Inst 96: 1204-1207 [Abstract] [Full Text]  
• van Roosmalen, M.S., Stalmeier, P.F.M., Verhoef, L.C.G., Hoekstra-Weebers, J.E.H.M., Oosterwijk, J.C., Hoogerbrugge, N., Moog, U., van Daal, W.A.J. (2004). Randomized Trial of a Shared Decision-Making Intervention Consisting of Trade-Offs and Individualized Treatment Information for BRCA1/2 Mutation Carriers. JCO 22: 3293-3301 [Abstract] [Full Text]