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Volume 336:1401-1408 May 15, 1997 Number 20 Next

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From the Division of Cancer Epidemiology and Genetics, National Cancer Institute (J.P.S., P.H., S.W., M.A.T.), and the Laboratory of Gene Transfer, National Human Genome Research Institute (J.P.S., S.M.B., M.M.T., L.C.B.), National Institutes of Health, Bethesda, Md.; Westat, Inc., Rockville, Md. (M.B.); and IMS, Inc., Silver Spring, Md. (M.M.).

Address reprint requests to Dr. Struewing at the Genetic Epidemiology Branch, Bldg. EPN, Rm. 439, 6130 Executive Blvd., MSC 7372, Bethesda, MD 20892-7372.

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N Engl J Med 1997; 337:787-789, Sep 11, 1997. Correspondence

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• Deng, C.-X. (2006). BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution. Nucleic Acids Res 34: 1416-1426 [Abstract] [Full Text]  
• Ryan, P. D., Harisinghani, M., Lerwill, M. F., Kaufman, D. S. (2006). Case records of the Massachusetts General Hospital. Case 6-2006. A 71-year-old woman with urinary incontinence and a mass in the bladder.. NEJM 354: 850-856 [Full Text]  
• Chen, S., Iversen, E. S., Friebel, T., Finkelstein, D., Weber, B. L., Eisen, A., Peterson, L. E., Schildkraut, J. M., Isaacs, C., Peshkin, B. N., Corio, C., Leondaridis, L., Tomlinson, G., Dutson, D., Kerber, R., Amos, C. I., Strong, L. C., Berry, D. A., Euhus, D. M., Parmigiani, G. (2006). Characterization of BRCA1 and BRCA2 Mutations in a Large United States Sample. JCO 24: 863-871 [Abstract] [Full Text]  
• Tryggvadottir, L., Sigvaldason, H., Olafsdottir, G. H., Jonasson, J. G., Jonsson, T., Tulinius, H., Eyfjord, J. E. (2006). Population-Based Study of Changing Breast Cancer Risk in Icelandic BRCA2 Mutation Carriers, 1920-2000. JNCI J Natl Cancer Inst 98: 116-122 [Abstract] [Full Text]  
• Ma, Y., Katiyar, P., Jones, L. P., Fan, S., Zhang, Y., Furth, P. A., Rosen, E. M. (2006). The Breast Cancer Susceptibility Gene BRCA1 Regulates Progesterone Receptor Signaling in Mammary Epithelial Cells. Mol. Endocrinol. 20: 14-34 [Abstract] [Full Text]  
• Kramer, J. L., Velazquez, I. A., Chen, B. E., Rosenberg, P. S., Struewing, J. P., Greene, M. H. (2005). Prophylactic Oophorectomy Reduces Breast Cancer Penetrance During Prospective, Long-Term Follow-Up of BRCA1 Mutation Carriers. JCO 23: 8629-8635 [Abstract] [Full Text]  
• Gogas, H., Markopoulos, C., Blamey, R. (2005). Should women be advised to take prophylactic endocrine treatment outside of a clinical trial setting?. Ann Oncol 16: 1861-1866 [Abstract] [Full Text]  
• Rebbeck, T. R., Friebel, T., Wagner, T., Lynch, H. T., Garber, J. E., Daly, M. B., Isaacs, C., Olopade, O. I., Neuhausen, S. L., van 't Veer, L., Eeles, R., Evans, D. G., Tomlinson, G., Matloff, E., Narod, S. A., Eisen, A., Domchek, S., Armstrong, K., Weber, B. L. (2005). Effect of Short-Term Hormone Replacement Therapy on Breast Cancer Risk Reduction After Bilateral Prophylactic Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group. JCO 23: 7804-7810 [Abstract] [Full Text]  
• Begg, C. B., Orlow, I., Hummer, A. J., Armstrong, B. K., Kricker, A., Marrett, L. D., Millikan, R. C., Gruber, S. B., Anton-Culver, H., Zanetti, R., Gallagher, R. P., Dwyer, T., Rebbeck, T. R., Mitra, N., Busam, K., From, L., Berwick, M., for the Genes Environment and Melanoma (GEM) Study, (2005). Lifetime Risk of Melanoma in CDKN2A Mutation Carriers in a Population-Based Sample. JNCI J Natl Cancer Inst 97: 1507-1515 [Abstract] [Full Text]  
• Miller, S. M., Roussi, P., Daly, M. B., Buzaglo, J. S., Sherman, K., Godwin, A. K., Balshem, A., Atchison, M. E. (2005). Enhanced Counseling for Women Undergoing BRCA1/2 Testing: Impact on Subsequent Decision Making About Risk Reduction Behaviors. Health Educ Behav 32: 654-667 [Abstract]  
• Zhang, Y., Fan, S., Meng, Q., Ma, Y., Katiyar, P., Schlegel, R., Rosen, E. M. (2005). BRCA1 Interaction with Human Papillomavirus Oncoproteins. J. Biol. Chem. 280: 33165-33177 [Abstract] [Full Text]  
• U.S. Preventive Services Task Force*, (2005). Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Recommendation Statement. ANN INTERN MED 143: 355-361 [Abstract] [Full Text]  
• Nelson, H. D., Huffman, L. H., Fu, R., Harris, E. L. (2005). Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Systematic Evidence Review for the U.S. Preventive Services Task Force. ANN INTERN MED 143: 362-379 [Abstract] [Full Text]  
• Rosen, E M, Fan, S, Isaacs, C (2005). BRCA1 in hormonal carcinogenesis: basic and clinical research. Endocr Relat Cancer 12: 533-548 [Abstract] [Full Text]  
• Hamann, H. A., Somers, T. J., Smith, A. W., Inslicht, S. S., Baum, A. (2005). Posttraumatic Stress Associated With Cancer History and BRCA1/2 Genetic Testing. Psychosom. Med. 67: 766-772 [Abstract] [Full Text]  
• van Asperen, C J, Brohet, R M, Meijers-Heijboer, E J, Hoogerbrugge, N, Verhoef, S, Vasen, H F A, Ausems, M G E M, Menko, F H, Gomez Garcia, E B, Klijn, J G M, Hogervorst, F B L, van Houwelingen, J C, van't Veer, L J, Rookus, M A, van Leeuwen, F E, on behalf of the Netherlands Collaborative Group o, (2005). Cancer risks in BRCA2 families: estimates for sites other than breast and ovary. J. Med. Genet. 42: 711-719 [Abstract] [Full Text]  
• Freedman, M. L., Penney, K. L., Stram, D. O., Riley, S., McKean-Cowdin, R., Le Marchand, L., Altshuler, D., Haiman, C. A. (2005). A Haplotype-Based Case-Control Study of BRCA1 and Sporadic Breast Cancer Risk. Cancer Res. 65: 7516-7522 [Abstract] [Full Text]  
• Wang, C., Fan, S., Li, Z., Fu, M., Rao, M., Ma, Y., Lisanti, M. P., Albanese, C., Katzenellenbogen, B. S., Kushner, P. J., Weber, B., Rosen, E. M., Pestell, R. G. (2005). Cyclin D1 Antagonizes BRCA1 Repression of Estrogen Receptor {alpha} Activity. Cancer Res. 65: 6557-6567 [Abstract] [Full Text]  
• Weitzel, J. N., Lagos, V., Blazer, K. R., Nelson, R., Ricker, C., Herzog, J., McGuire, C., Neuhausen, S. (2005). Prevalence of BRCA Mutations and Founder Effect in High-Risk Hispanic Families. Cancer Epidemiol. Biomarkers Prev. 14: 1666-1671 [Abstract] [Full Text]  
• Antoniou, A C, Pharoah, P D P, Narod, S, Risch, H A, Eyfjord, J E, Hopper, J L, Olsson, H, Johannsson, O, Borg, A, Pasini, B, Radice, P, Manoukian, S, Eccles, D M, Tang, N, Olah, E, Anton-Culver, H, Warner, E, Lubinski, J, Gronwald, J, Gorski, B, Tulinius, H, Thorlacius, S, Eerola, H, Nevanlinna, H, Syrjakoski, K, Kallioniemi, O-P, Thompson, D, Evans, C, Peto, J, Lalloo, F, Evans, D G, Easton, D F (2005). Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies. J. Med. Genet. 42: 602-603 [Abstract] [Full Text]  
• Cook, J. D., Davis, B. J., Cai, S.-L., Barrett, J. C., Conti, C. J., Walker, C. L. (2005). Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance. Proc. Natl. Acad. Sci. USA 102: 8644-8649 [Abstract] [Full Text]  
• Weitzel, J. N., Robson, M., Pasini, B., Manoukian, S., Stoppa-Lyonnet, D., Lynch, H. T., McLennan, J., Foulkes, W. D., Wagner, T., Tung, N., Ghadirian, P., Olopade, O., Isaacs, C., Kim-Sing, C., Moller, P., Neuhausen, S. L., Metcalfe, K., Sun, P., Narod, S. A. (2005). A Comparison of Bilateral Breast Cancers in BRCA Carriers. Cancer Epidemiol. Biomarkers Prev. 14: 1534-1538 [Abstract] [Full Text]  
• Eberl, M. M., Sunga, A. Y., Farrell, C. D., Mahoney, M. C. (2005). Patients with a Family History of Cancer: Identification and Management. J Am Board Fam Med 18: 211-217 [Abstract] [Full Text]  
• Simeone, A.-M., Deng, C.-X., Kelloff, G. J., Steele, V. E., Johnson, M. M., Tari, A. M. (2005). N-(4-Hydroxyphenyl)retinamide is more potent than other phenylretinamides in inhibiting the growth of BRCA1-mutated breast cancer cells. Carcinogenesis 26: 1000-1007 [Abstract] [Full Text]  
• Schwartz, M. D., Lerman, C., Brogan, B., Peshkin, B. N., Isaacs, C., DeMarco, T., Hughes Halbert, C., Pennanen, M., Finch, C. (2005). Utilization of BRCA1/BRCA2 Mutation Testing in Newly Diagnosed Breast Cancer Patients. Cancer Epidemiol. Biomarkers Prev. 14: 1003-1007 [Abstract] [Full Text]  
• Patterson, A. R., Robinson, L. D., Naftalis, E. Z., Haley, B. B., Tomlinson, G. E. (2005). Custodianship of Genetic Information: Clinical Challenges and Professional Responsibility. JCO 23: 2100-2104 [Full Text]  
• Gurmankin, A. D., Domchek, S., Stopfer, J., Fels, C., Armstrong, K. (2005). Patients' Resistance to Risk Information in Genetic Counseling for BRCA1/2. Arch Intern Med 165: 523-529 [Abstract] [Full Text]