From the Departments of Neurosciences (B.D.T., J.P., R.M.R., R.R., L.B.) and Neurology (R.M.R., R.R.), Lerner Research Institute, and the Mellen Center for Multiple Sclerosis Research (R.M.R., R.R.), Cleveland Clinic Foundation, Cleveland; and the Department of Pathology, Haukeland Hospital, Bergen, Norway (S.M.).
Address reprint requests to Dr. Trapp at the Department of Neurosciences, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195.
Tsutsui, S., Hahn, J. N., Johnson, T. A., Ali, Z., Jirik, F. R.
(2008). Absence of the Cellular Prion Protein Exacerbates and Prolongs Neuroinflammation in Experimental Autoimmune Encephalomyelitis. Am. J. Pathol.
173: 1029-1041
[Abstract][Full Text]
Wilkins, A, Scolding, N
(2008). Protecting axons in multiple sclerosis. Mult Scler
14: 1013-1025
[Abstract]
Chang, A., Smith, M. C., Yin, X., Fox, R. J., Staugaitis, S. M., Trapp, B. D.
(2008). Neurogenesis in the chronic lesions of multiple sclerosis. Brain
131: 2366-2375
[Abstract][Full Text]
Diem, R., Demmer, I., Boretius, S., Merkler, D., Schmelting, B., Williams, S. K., Sattler, M. B., Bahr, M., Michaelis, T., Frahm, J., Bruck, W., Fuchs, E.
(2008). Autoimmune Optic Neuritis in the Common Marmoset Monkey: Comparison of Visual Evoked Potentials with MRI and Histopathology. IOVS
49: 3707-3714
[Abstract][Full Text]
Zivadinov, R., Reder, A. T., Filippi, M., Minagar, A., Stuve, O., Lassmann, H., Racke, M. K., Dwyer, M. G., Frohman, E. M., Khan, O.
(2008). Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis. Neurology
71: 136-144
[Abstract][Full Text]
Kezele, I., Arnold, D., Collins, D.
(2008). Atrophy in white matter fiber tracts in multiple sclerosis is not dependent on tract length or local white matter lesions. Mult Scler
14: 779-785
[Abstract]
Bar-Zohar, D, Agosta, F, Goldstaub, D, Filippi, M
(2008). Magnetic resonance imaging metrics and their correlation with clinical outcomes in multiple sclerosis: a review of the literature and future perspectives. Mult Scler
14: 719-727
[Abstract]
Anderson, J. M., Hampton, D. W., Patani, R., Pryce, G., Crowther, R. A., Reynolds, R., Franklin, R. J. M., Giovannoni, G., Compston, D. A. S., Baker, D., Spillantini, M. G., Chandran, S.
(2008). Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis. Brain
131: 1736-1748
[Abstract][Full Text]
Minden, S, Hoaglin, D, Jureidini, S, Hadden, L, Frankel, D, Komatsuzaki, Y, Outley, J
(2008). Disease-modifying agents in the Sonya Slifka Longitudinal Multiple Sclerosis Study. Mult Scler
14: 640-655
[Abstract]
Pueyo, V, Martin, J, Fernandez, J, Almarcegui, C, Ara, J, Egea, C, Pablo, L, Honrubia, F
(2008). Axonal loss in the retinal nerve fiber layer in patients with multiple sclerosis. Mult Scler
14: 609-614
[Abstract]
Mizuno, T., Zhang, G., Takeuchi, H., Kawanokuchi, J., Wang, J., Sonobe, Y., Jin, S., Takada, N., Komatsu, Y., Suzumura, A.
(2008). Interferon-{gamma} directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-{gamma} receptor and AMPA GluR1 receptor. FASEB J.
22: 1797-1806
[Abstract][Full Text]
Irvine, K. A., Blakemore, W. F.
(2008). Remyelination protects axons from demyelination-associated axon degeneration. Brain
131: 1464-1477
[Abstract][Full Text]
Villar, L., Garcia-Barragan, N., Espino, M., Roldan, E., Sadaba, M., Gomez-Rial, J., Gonzalez-Porque, P., Alvarez-Cermeno, J.
(2008). Influence of oligoclonal IgM specificity in multiple sclerosis disease course. Mult Scler
14: 183-187
[Abstract]
Zivadinov, R., Banas, A.C., Yella, V., Abdelrahman, N., Weinstock-Guttman, B., Dwyer, M.G.
(2008). Comparison of Three Different Methods for Measurement of Cervical Cord Atrophy in Multiple Sclerosis. Am. J. Neuroradiol.
29: 319-325
[Abstract][Full Text]
Nash, R. A., Stuve, O., Bowen, J. D., Frohman, E. M., Griffith, L. M., Hutton, G. J., Kraft, G. H., Popat, U., Racke, M. K., Muraro, P. A.
(2008). Autologous HSCT for advanced MS: Is the glass half-empty or really half-full?. Brain
131: e89-e89
[Full Text]
Minagar, A., Alexander, J. S., Schwendimann, R. N., Kelley, R. E., Gonzalez-Toledo, E., Jimenez, J. J., Mauro, L., Jy, W., Smith, S. J.
(2008). Combination Therapy With Interferon Beta-1a and Doxycycline in Multiple Sclerosis: An Open-Label Trial. Arch Neurol
65: 199-204
[Abstract][Full Text]
Henderson, A. P. D., Trip, S. A., Schlottmann, P. G., Altmann, D. R., Garway-Heath, D. F., Plant, G. T., Miller, D. H.
(2008). An investigation of the retinal nerve fibre layer in progressive multiple sclerosis using optical coherence tomography. Brain
131: 277-287
[Abstract][Full Text]
Benveniste, E. N., Qin, H.
(2007). Type I Interferons as Anti-Inflammatory Mediators. Sci Signal
2007: pe70-pe70
[Abstract][Full Text]
Qi, X., Sun, L., Lewin, A. S., Hauswirth, W. W., Guy, J.
(2007). Long-term Suppression of Neurodegeneration in Chronic Experimental Optic Neuritis: Antioxidant Gene Therapy. IOVS
48: 5360-5370
[Abstract][Full Text]
Pulicken, M., Gordon-Lipkin, E., Balcer, L. J., Frohman, E., Cutter, G., Calabresi, P. A.
(2007). Optical coherence tomography and disease subtype in multiple sclerosis. Neurology
69: 2085-2092
[Abstract][Full Text]
Zivadinov, R., Weinstock-Guttman, B., Benedict, R., Tamano-Blanco, M., Hussein, S., Abdelrahman, N., Durfee, J., Ramanathan, M.
(2007). Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor. Hum Mol Genet
16: 2659-2668
[Abstract][Full Text]
De Stefano, N., Filippi, M., Miller, D., Pouwels, P. J., Rovira, A., Gass, A., Enzinger, C., Matthews, P. M., Arnold, D. L.
(2007). Guidelines for using proton MR spectroscopy in multicenter clinical MS studies. Neurology
69: 1942-1952
[Abstract][Full Text]
Meier, D.S., Weiner, H.L., Guttmann, C.R.G.
(2007). MR Imaging Intensity Modeling of Damage and Repair In Multiple Sclerosis: Relationship of Short-Term Lesion Recovery to Progression and Disability. Am. J. Neuroradiol.
28: 1956-1963
[Abstract][Full Text]
Hoftberger, R., Garzuly, F., Dienes, H.P., Grubits, J., Rohonyi, B., Fischer, G., Hanzely, Z., Lassmann, H., Budka, H.
(2007). Fulminant central nervous system demyelination associated with interferon-{alpha} therapy and hepatitis C virus infection. Mult Scler
13: 1100-1106
[Abstract]
Marik, C., Felts, P. A., Bauer, J., Lassmann, H., Smith, K. J.
(2007). Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?. Brain
130: 2800-2815
[Abstract][Full Text]
Tomassini, V., De Giglio, L., Reindl, M., Russo, P., Pestalozza, I., Pantano, P., Berger, T., Pozzilli, C.
(2007). Anti-myelin antibodies predict the clinical outcome after a first episode suggestive of MS. Mult Scler
13: 1086-1094
[Abstract]
Rasmussen, S., Wang, Y., Kivisakk, P., Bronson, R. T., Meyer, M., Imitola, J., Khoury, S. J.
(2007). Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing remitting experimental autoimmune encephalomyelitis. Brain
130: 2816-2829
[Abstract][Full Text]
Tsunoda, I., Tanaka, T., Saijoh, Y., Fujinami, R. S.
(2007). Targeting Inflammatory Demyelinating Lesions to Sites of Wallerian Degeneration. Am. J. Pathol.
171: 1563-1575
[Abstract][Full Text]
Klistorner, A., Graham, S., Fraser, C., Garrick, R., Nguyen, T., Paine, M., O'Day, J., Grigg, J., Arvind, H., Billson, F. A.
(2007). Electrophysiological Evidence for Heterogeneity of Lesions in Optic Neuritis. IOVS
48: 4549-4556
[Abstract][Full Text]
Dutta, R., McDonough, J., Chang, A., Swamy, L., Siu, A., Kidd, G. J., Rudick, R., Mirnics, K., Trapp, B. D.
(2007). Activation of the ciliary neurotrophic factor (CNTF) signalling pathway in cortical neurons of multiple sclerosis patients. Brain
130: 2566-2576
[Abstract][Full Text]
Rocca, M.A., Mondria, T., Valsasina, P., Sormani, M.P., Flach, Z.H., Te Boekhorst, P.A., Comi, G., Hintzen, R.Q., Filippi, M.
(2007). A Three-Year Study of Brain Atrophy after Autologous Hematopoietic Stem Cell Transplantation in Rapidly Evolving Secondary Progressive Multiple Sclerosis. Am. J. Neuroradiol.
28: 1659-1661
[Abstract][Full Text]
Mathey, E. K., Derfuss, T., Storch, M. K., Williams, K. R., Hales, K., Woolley, D. R., Al-Hayani, A., Davies, S. N., Rasband, M. N., Olsson, T., Moldenhauer, A., Velhin, S., Hohlfeld, R., Meinl, E., Linington, C.
(2007). Neurofascin as a novel target for autoantibody-mediated axonal injury. J. Exp. Med.
204: 2363-2372
[Abstract][Full Text]
Williams, A., Piaton, G., Aigrot, M.-S., Belhadi, A., Theaudin, M., Petermann, F., Thomas, J.-L., Zalc, B., Lubetzki, C.
(2007). Semaphorin 3A and 3F: key players in myelin repair in multiple sclerosis?. Brain
130: 2554-2565
[Abstract][Full Text]
Houtchens, M. K., Benedict, R.H.B., Killiany, R., Sharma, J., Jaisani, Z., Singh, B., Weinstock-Guttman, B., Guttmann, C. R.G., Bakshi, R.
(2007). Thalamic atrophy and cognition in multiple sclerosis. Neurology
69: 1213-1223
[Abstract][Full Text]
Roccatagliata, L., Rocca, M., Valsasina, P., Bonzano, L., Sormani, M., Saccardi, R., Mancardi, G., Filippi, M., for the Italian GITMO-NEURO Intergroup on Autologo,
(2007). The long-term effect of AHSCT on MRI measures of MS evolution: a five-year follow-up study. Mult Scler
13: 1068-1070
[Abstract]
The International Multiple Sclerosis Genetics Cons,
(2007). Risk Alleles for Multiple Sclerosis Identified by a Genomewide Study. NEJM
357: 851-862
[Abstract][Full Text]
Shindler, K. S., Ventura, E., Rex, T. S., Elliott, P., Rostami, A.
(2007). SIRT1 Activation Confers Neuroprotection in Experimental Optic Neuritis. IOVS
48: 3602-3609
[Abstract][Full Text]
Amato, M. P., Portaccio, E., Goretti, B., Zipoli, V., Battaglini, M., Bartolozzi, M. L., Stromillo, M. L., Guidi, L., Siracusa, G., Sorbi, S., Federico, A., De Stefano, N.
(2007). Association of Neocortical Volume Changes With Cognitive Deterioration in Relapsing-Remitting Multiple Sclerosis. Arch Neurol
64: 1157-1161
[Abstract][Full Text]
DeBoy, C. A., Zhang, J., Dike, S., Shats, I., Jones, M., Reich, D. S., Mori, S., Nguyen, T., Rothstein, B., Miller, R. H., Griffin, J. T., Kerr, D. A., Calabresi, P. A.
(2007). High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord. Brain
130: 2199-2210
[Abstract][Full Text]
Nessler, S., Boretius, S., Stadelmann, C., Bittner, A., Merkler, D., Hartung, H.-P., Michaelis, T., Bruck, W., Frahm, J., Sommer, N., Hemmer, B.
(2007). Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage. Brain
130: 2186-2198
[Abstract][Full Text]
Benedict, R. H.B., Bruce, J., Dwyer, M. G., Weinstock-Guttman, B., Tjoa, C., Tavazzi, E., Munschauer, F. E., Zivadinov, R.
(2007). Diffusion-weighted imaging predicts cognitive impairment in multiple sclerosis. Mult Scler
13: 722-730
[Abstract]
Vrenken, H., Pouwels, P.J.W., Ropele, S., Knol, D.L., Geurts, J.J.G., Polman, C.H., Barkhof, F., Castelijns, J.A.
(2007). Magnetization transfer ratio measurement in multiple sclerosis normal-appearing brain tissue: limited differences with controls but relationships with clinical and MR measures of disease. Mult Scler
13: 708-716
[Abstract]
Thrower, B. W.
(2007). Clinically isolated syndromes: Predicting and delaying multiple sclerosis. Neurology
68: S12-S15
[Abstract][Full Text]
Birnbaum, G., Leist, T. P., Lublin, F. D.
(2007). Commentary I: Pathophysiologic construct for neuronal degeneration/regeneration in multiple sclerosis. Neurology
68: S2-S4
[Full Text]
Lisak, R. P.
(2007). Neurodegeneration in multiple sclerosis: Defining the problem. Neurology
68: S5-S12
[Abstract][Full Text]
Dutta, R., Trapp, B. D.
(2007). Pathogenesis of axonal and neuronal damage in multiple sclerosis. Neurology
68: S22-S31
[Abstract][Full Text]
Yong, V. W., Giuliani, F., Xue, M., Bar-Or, A., Metz, L. M.
(2007). Experimental models of neuroprotection relevant to multiple sclerosis. Neurology
68: S32-S37
[Abstract][Full Text]
Birnbaum, G., Leist, T. P., Lublin, F. D.
(2007). Commentary II: Clinical aspects of assessing neuronal health in multiple sclerosis. Neurology
68: S55-S57
[Full Text]
Zivadinov, R.
(2007). Can imaging techniques measure neuroprotection and remyelination in multiple sclerosis?. Neurology
68: S72-S82
[Abstract][Full Text]
Zivadinov, R., Locatelli, L., Cookfair, D., Srinivasaraghavan, B., Bertolotto, A., Ukmar, M., Bratina, A., Maggiore, C., Bosco, A., Grop, A., Catalan, M., Zorzon, M.
(2007). I nterferon beta-1a slows progression of brain atrophy in relapsing-remitting multiple sclerosis predominantly by reducing gray matter atrophy. Mult Scler
13: 490-501
[Abstract]
AL-Sabbagh, A.
(2007). Neutralizing antibodies in MS therapy: reviewing the Rebif experience. Mult Scler
13: 8-13
[Abstract]
Metz, I., Lucchinetti, C. F., Openshaw, H., Garcia-Merino, A., Lassmann, H., Freedman, M. S., Atkins, H. L., Azzarelli, B., Kolar, O. J., Bruck, W.
(2007). Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis. Brain
130: 1254-1262
[Abstract][Full Text]
Misu, T., Fujihara, K., Kakita, A., Konno, H., Nakamura, M., Watanabe, S., Takahashi, T., Nakashima, I., Takahashi, H., Itoyama, Y.
(2007). Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis. Brain
130: 1224-1234
[Abstract][Full Text]
Forte, M., Gold, B. G., Marracci, G., Chaudhary, P., Basso, E., Johnsen, D., Yu, X., Fowlkes, J., Rahder, M., Stem, K., Bernardi, P., Bourdette, D.
(2007). Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. Proc. Natl. Acad. Sci. USA
104: 7558-7563
[Abstract][Full Text]
Chitnis, T., Imitola, J., Wang, Y., Elyaman, W., Chawla, P., Sharuk, M., Raddassi, K., Bronson, R. T., Khoury, S. J.
(2007). Elevated Neuronal Expression of CD200 Protects Wlds Mice from Inflammation-Mediated Neurodegeneration. Am. J. Pathol.
170: 1695-1712
[Abstract][Full Text]
Miller, D. H., Soon, D., Fernando, K. T., MacManus, D. G., Barker, G. J., Yousry, T. A., Fisher, E., O'Connor, P. W., Phillips, J. T., Polman, C. H., Kappos, L., Hutchinson, M., Havrdova, E., Lublin, F. D., Giovannoni, G., Wajgt, A., Rudick, R., Lynn, F., Panzara, M. A., Sandrock, A. W., For the AFFIRM Investigators,
(2007). MRI outcomes in a placebo-controlled trial of natalizumab in relapsing MS. Neurology
68: 1390-1401
[Abstract][Full Text]
Saindane, A.M., Law, M., Ge, Y., Johnson, G., Babb, J.S., Grossman, R.I.
(2007). Correlation of Diffusion Tensor and Dynamic Perfusion MR Imaging Metrics in Normal-Appearing Corpus Callosum: Support for Primary Hypoperfusion in Multiple Sclerosis. Am. J. Neuroradiol.
28: 767-772
[Abstract][Full Text]
Magliozzi, R., Howell, O., Vora, A., Serafini, B., Nicholas, R., Puopolo, M., Reynolds, R., Aloisi, F.
(2007). Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain
130: 1089-1104
[Abstract][Full Text]
O'Rourke, K., Walsh, C., Antonelli, G., Hutchinson, M.
(2007). Predicting beta-interferon failure in relapsing-remitting multiple sclerosis. Mult Scler
13: 336-342
[Abstract]
Rashid, W, Davies, G R, Chard, D T, Griffin, C M, Altmann, D R, Thompson, A J, Miller, D H
(2007). Relationship of triple dose contrast enhanced lesions with clinical measures and brain atrophy in early relapsing-remitting multiple sclerosis: a two-year longitudinal study. Mult Scler
13: 178-185
[Abstract]
Gonen, O., Oberndorfer, T.A., Inglese, M., Babb, J.S., Herbert, J., Grossman, R.I.
(2007). Reproducibility of Three Whole-Brain N-Acetylaspartate Decline Cohorts in Relapsing-Remitting Multiple Sclerosis. Am. J. Neuroradiol.
28: 267-271
[Abstract][Full Text]
Cianfoni, A., Niku, S., Imbesi, S.G.
(2007). Metabolite Findings in Tumefactive Demyelinating Lesions Utilizing Short Echo Time Proton Magnetic Resonance Spectroscopy. Am. J. Neuroradiol.
28: 272-277
[Abstract][Full Text]
Qi, X., Lewin, A. S., Sun, L., Hauswirth, W. W., Guy, J.
(2007). Suppression of Mitochondrial Oxidative Stress Provides Long-term Neuroprotection in Experimental Optic Neuritis. IOVS
48: 681-691
[Abstract][Full Text]
Hensiek, A. E., Seaman, S. R., Barcellos, L. F., Oturai, A., Eraksoi, M., Cocco, E., Vecsei, L., Stewart, G., Dubois, B., Bellman-Strobl, J., Leone, M., Andersen, O., Bencsik, K., Booth, D., Celius, E. G., Harbo, H. F., Hauser, S. L., Heard, R., Hillert, J., Myhr, K. -M., Marrosu, M. G., Oksenberg, J. R., Rajda, C., Sawcer, S. J., Sorensen, P. S., Zipp, F., Compston, D.A.S.
(2007). Familial effects on the clinical course of multiple sclerosis. Neurology
68: 376-383
[Abstract][Full Text]
Wattjes, M.P., Lutterbey, G.G., Gieseke, J., Traber, F., Klotz, L., Schmidt, S., Schild, H.H.
(2007). Double Inversion Recovery Brain Imaging at 3T: Diagnostic Value in the Detection of Multiple Sclerosis Lesions. Am. J. Neuroradiol.
28: 54-59
[Abstract][Full Text]
Tsunoda, I., Tanaka, T., Terry, E. J., Fujinami, R. S.
(2007). Contrasting Roles for Axonal Degeneration in an Autoimmune versus Viral Model of Multiple Sclerosis: When Can Axonal Injury Be Beneficial?. Am. J. Pathol.
170: 214-226
[Abstract][Full Text]
Smith, K. J.
(2006). Axonal protection in multiple sclerosis--a particular need during remyelination?. Brain
129: 3147-3149
[Full Text]
Black, J. A., Liu, S., Hains, B. C., Saab, C. Y., Waxman, S. G.
(2006). Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE. Brain
129: 3196-3208
[Abstract][Full Text]
Howell, O. W., Palser, A., Polito, A., Melrose, S., Zonta, B., Scheiermann, C., Vora, A. J., Brophy, P. J., Reynolds, R.
(2006). Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis. Brain
129: 3173-3185
[Abstract][Full Text]
Stagi, M., Gorlovoy, P., Larionov, S., Takahashi, K., Neumann, H.
(2006). Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway. FASEB J.
20: 2573-2575
[Abstract][Full Text]
Saccardi, R, Kozak, T, Bocelli-Tyndall, C, Fassas, A, Kazis, A, Havrdova, E, Carreras, E, Saiz, A, Lowenberg, B, te Boekhorst, P A., Gualandi, F, Openshaw, H, Longo, G, Pagliai, F, Massacesi, L, Deconink, E, Ouyang, J, Nagore, F J., Besalduch, J, Lisukov, I A, Bonini, A, Merelli, E, Slavin, S, Gratwohl, A, Passweg, J, Tyndall, A, Steck, A J, Andolina, M, Capobianco, M, Martin, J L., Lugaresi, A, Meucci, G, Saez, R A, Clark, R E, Fernandez, M N, Fouillard, L, Herstenstein, B, Koza, V, Cocco, E, Baurmann, H, Mancardi, G L, Autoimmune Diseases Working Party of EBMT,
(2006). Autologous stem cell transplantation for progressive multiple sclerosis: Update of the European Group for Blood and Marrow Transplantation autoimmune diseases working party database. Mult Scler
12: 814-823
[Abstract]
Qi, X., Lewin, A. S., Sun, L., Hauswirth, W. W., Guy, J.
(2006). Mitochondrial Protein Nitration Primes Neurodegeneration in Experimental Autoimmune Encephalomyelitis. J. Biol. Chem.
281: 31950-31962
[Abstract][Full Text]
Kolln, J., Ren, H.-M., Da, R.-R., Zhang, Y., Spillner, E., Olek, M., Hermanowicz, N., Hilgenberg, L. G., Smith, M. A., van den Noort, S., Qin, Y.
(2006). Triosephosphate Isomerase- and Glyceraldehyde-3-Phosphate Dehydrogenase-Reactive Autoantibodies in the Cerebrospinal Fluid of Patients with Multiple Sclerosis. J. Immunol.
177: 5652-5658
[Abstract][Full Text]
Kappos, L., Polman, C. H., Freedman, M. S., Edan, G., Hartung, H. P., Miller, D. H., Montalban, X., Barkhof, F., Bauer, L., Jakobs, P., Pohl, C., Sandbrink, R., for the BENEFIT Study Group,
(2006). Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes. Neurology
67: 1242-1249
[Abstract][Full Text]
Vrenken, H., Geurts, J.J.G., Knol, D.L., Polman, C.H., Castelijns, J.A., Pouwels, P.J.W., Barkhof, F.
(2006). Normal-appearing white matter changes vary with distance to lesions in multiple sclerosis.. Am. J. Neuroradiol.
27: 2005-2011
[Abstract][Full Text]
Maier, K., Kuhnert, A. V., Taheri, N., Sattler, M. B., Storch, M. K., Williams, S. K., Bahr, M., Diem, R.
(2006). Effects of Glatiramer Acetate and Interferon-{beta} on Neurodegeneration in a Model of Multiple Sclerosis: A Comparative Study. Am. J. Pathol.
169: 1353-1364
[Abstract][Full Text]
Agosta, F., Rovaris, M., Pagani, E., Sormani, M. P., Comi, G., Filippi, M.
(2006). Magnetization transfer MRI metrics predict the accumulation of disability 8 years later in patients with multiple sclerosis. Brain
129: 2620-2627
[Abstract][Full Text]
Kaneko, S., Wang, J., Kaneko, M., Yiu, G., Hurrell, J. M., Chitnis, T., Khoury, S. J., He, Z.
(2006). Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models.. J. Neurosci.
26: 9794-9804
[Abstract][Full Text]
Kappos, L., Antel, J., Comi, G., Montalban, X., O'Connor, P., Polman, C. H., Haas, T., Korn, A. A., Karlsson, G., Radue, E. W., the FTY720 D2201 Study Group,
(2006). Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis. NEJM
355: 1124-1140
[Abstract][Full Text]
West, T., Wyatt, M., High, A., Bostrom, A., Waubant, E.
(2006). Are initial demyelinating event recovery and time to second event under differential control?. Neurology
67: 809-813
[Abstract][Full Text]
Shindler, K. S, Guan, Y., Ventura, E., Bennett, J., Rostami, A.
(2006). Retinal ganglion cell loss induced by acute optic neuritis in a relapsing model of multiple sclerosis. Mult Scler
12: 526-532
[Abstract]
Sotgiu, S, Barone, R, Arru, G, Fois, M L, Pugliatti, M, Sanna, A, Rosati, G, Musumeci, S
(2006). Intrathecal chitotriosidase and the outcome of multiple sclerosis. Mult Scler
12: 551-557
[Abstract]
Previous
