To the Editor: Maternal cigarette smoking during pregnancy isassociated with fetal risks in the short and long term1,2. Anyattempt to understand the effects of maternal smoking on thefetus should include an estimate of the degree of fetal exposureto the constituents of cigarette smoke. To date, no biologicmarkers have been identified that can assist in such an estimation.We describe the distribution characteristics of nicotine andits metabolite cotinine in maternal and fetal hair.
We studied 10 smoking and 11 nonsmoking mothers (mean ages,19 and 20 years, respectively) in two hospitals in Toronto.From . . . [Full Text of this Article]
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