The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Original Article
Brief Report
PreviousPrevious
Volume 328:703-706 March 11, 1993 Number 10
NextNext

Trimethoprim-Induced Hyperkalemia in a Patient with AIDS
Michael J. Choi, Pedro C. Fernandez, Asit Patnaik, Brigitte Coupaye-Gerard, Denise D'Andrea, Harold Szerlip, and Thomas R. Kleyman

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited

More Information
-PubMed Citation
Hyperkalemia has been reported in 16 to 21 percent of patients hospitalized with the acquired immunodeficiency syndrome (AIDS)1,2,3. Although renal failure often accompanies hyperkalemia,1,2 AIDS is associated with other abnormalities that impair renal excretion of potassium, such as adrenal insufficiency and hypoaldosteronism3,4,5,6,7. Adrenal insufficiency and hypoaldosteronism, however, are rare in patients with AIDS4,5.

Hyperkalemia develops in 20 to 53 percent of patients with AIDS while they are receiving high doses of trimethoprim in combination with sulfamethoxazole or dapsone for the treatment of Pneumocystis carinii pneumonia8. We recently encountered a patient with AIDS and P. carinii pneumonia . . . [Full Text of this Article]

Case Report

Methods

Materials

Electrophysiologic Measurements

Transtubular Potassium-Concentration Gradient

Results

Discussion


Source Information

From the Philadelphia Veterans Affairs Medical Center (M.J.C., P.C.F., D.D., H.S., T.R.K.); the Renal and Electrolyte Division, Departments of Medicine (M.J.C., P.C.F., A.P., B.C.-G., D.D., H.S., T.R.K.) and Physiology (T.R.K.), University of Pennsylvania; and the Department of Medicine, Medical College of Pennsylvania (P.C.F.) -- all in Philadelphia.

Address reprint requests to Dr. Kleyman at Medical Research (151), Veterans Affairs Medical Center, Philadelphia, PA 19104.

References


This article has been cited by other articles:



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.