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Previous Volume 328:1023-1030 April 8, 1993 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The disorders classified as non-Hodgkin's lymphoma are increasing in frequency in the United States, with more than 35,000 cases diagnosed annually. In recent years, there have been numerous advances in our understanding of the biology of these disorders and in their treatment. In this article, these advances will be reviewed in the same order as a physician should consider them when seeing a new patient with non-Hodgkin's lymphoma: the diagnosis is considered first, followed by the prognosis, choice of treatment, and treatment itself.

Clinically Important Subtypes of Non-Hodgkin's Lymphoma

Unlike the related disorder Hodgkin's disease, non-Hodgkin's lymphoma has a firmly established cellular origin with morphologic subtypes . . . [Full Text of this Article]

Factors Predicting Treatment Outcome

Stage

Immunologic Characteristics

Genetic Abnormalities

Tumor-Proliferation Rate

Principles of Therapy

Localized Disease

Disseminated Disease (Bulky Stage II and Stages III and IV)

Therapy in Children

Therapy in Elderly Patients

Therapy in Patients with Human Immunodeficiency Virus Infection

Treatment of Recurrent Disease

Conclusion

Source Information

From the Department of Internal Medicine, University of Nebraska Medical Center, 600 S. 42nd St., Omaha, NE 68198-3332, where reprint requests should be addressed to Dr. Armitage.

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