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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 328:1031-1035 April 8, 1993 Number 14
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Case 14-1993— A 74-Year-Old Woman with Hyperparathyroidism and an Osteolytic Lesion in the Humerus
Michael M. Lewis, and John X. O'Connell

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Presentation of Case

A 74-year-old woman was admitted to the hospital because of hypercalcemia and an osteolytic bone lesion.

The patient had been in good health until six years earlier, when hypercalcemia was discovered. The alkaline phosphatase was increased, and the parathyroid hormone was six times the upper limit of normal. The calcium rose as high as 13.6 mg per deciliter (3.4 mmol per liter), although the patient denied all symptoms. An ultrasonographic examination of the neck was said to show no definite evidence of a parathyroid adenoma.

Thereafter the patient continued to feel well except for intermittent fatigue until three months before . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnosis

Dr. Michael M. Lewis' Diagnosis

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Anatomical Diagnosis

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