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Previous Volume 328:1121-1124 April 15, 1993 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Agnello et al. (Nov. 19 issue)¹ report the detection of hepatitis C virus (HCV) RNA in serum samples from 16 of 19 patients with type II cryoglobulinemia. Using three different assays, they demonstrated antibodies to HCV in the samples from only 8 of the 16 patients positive for HCV RNA and in one of four cryoprecipitates from the patients positive for antibodies to HCV. These findings are surprisingly different from those obtained by several investigators using quite similar assays^2,3,4. In our series of 51 patients with essential mixed cryoglobulinemia⁴ and in 24 additional patients subsequently studied, . . . [Full Text of this Article]

References

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• Ramos-Casals, M., Trejo, O., Garcia-Carrasco, M., Cervera, R., Font, J. (2000). Mixed cryoglobulinemia: new concepts. Lupus 9: 83-91 [Abstract]  
• Fernandez-Gutierrez, B., Zamorano, J., Batlle, E., Alfonso, F., Conde, A., Sanchez-Harguindey, L., Jover, J. A. (1999). Coronary dissection associated with hepatitis C virus-related cryoglobulinaemia. Rheumatology (Oxford) 38: 1299-1301 [Full Text]  
• Cresta, P, Musset, L, Cacoub, P, Frangeul, L, Vitour, D, Poynard, T, Opolon, P, Nguyen, D-T, Golliot, F, Piette, J-C, Huraux, J-M, Lunel, F (1999). Response to interferon alpha  treatment and disappearance of cryoglobulinaemia in patients infected by hepatitis C virus. Gut 45: 122-128 [Abstract] [Full Text]  
• Cacoub, P., Boukli, N., Hausfater, P., Garbarg-Chenon, A., Ghillani, P., Thibault, V., Musset, L., Huraux, J. M., Piette, J.-C. (1998). Parvovirus B19 infection, hepatitis C virus infection, and mixed cryoglobulinaemia. Ann Rheum Dis 57: 422-424 [Abstract] [Full Text]  
• Pawlotsky, J.-M., Dhumeaux, D., Bagot, M. (1995). Hepatitis C Virus in Dermatology: A Review. Arch Dermatol 131: 1185-1193 [Abstract]  
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