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Correspondence
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Volume 328:139-140 January 14, 1993 Number 2
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Possibly Disappointing Results of Treatment with Gemfibrozil

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To the Editor: Many readers may have missed one of the most interesting items in the September 3 issue of the Journal: the fine print on the back of an advertisement for the Lopid brand of gemfibrozil. Gemfibrozil reduced the incidence of coronary events in the landmark Helsinki Heart Study, reported in the Journal in 19871. However, additional information about gemfibrozil that has since become available has received much less attention.

The Warnings section of the prescribing information begins with a reminder that gemfibrozil is chemically, pharmacologically, and clinically similar to clofibrate, which was found in a World Health . . . [Full Text of this Article]

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