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Correspondence
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Volume 328:1715 June 10, 1993 Number 23
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Protective Effect or Symptomatic Effect of Deprenyl?

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 by The Parkinson Study Group
To the Editor: Is it not time to read between the lines? The recent partial retraction of the preliminary, enthusiastic report after additional follow-up by the Parkinson Study Group (Jan. 21 issue)1 has greatly diminished the previous claims of a protective effect of deprenyl in patients with early untreated Parkinson's disease and has enhanced the known symptomatic effect of this agent2,3.

Many obvious questions remain. Why have the results of objective biochemical studies related to the predicted attenuation of cerebrospinal fluid homovanillic acid that was an important part of the initial protocol4 not been revealed? Have these findings not . . . [Full Text of this Article]

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