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Book Review
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Volume 328:1721-1722 June 10, 1993 Number 23
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Handbook of Amyotrophic Lateral Sclerosis

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Edited by Richard Alan Smith. 783 pp., illustrated. New York, Marcel Dekker, 1992. $195. ISBN 0-8247-8610-6.

These are exciting times for investigators of neuromuscular diseases. With the explosion of information about the human genome, we are advancing on the mysteries of many diseases, such as Duchenne's muscular dystrophy, that were formerly thought to be unsolvable. Exciting advances in research on amyotrophic lateral sclerosis include the identification of the locus for the gene in familial cases, the identification of unique electrophysiologic features that herald a more benign prognosis for some patients, and the recognition of immunologic abnormalities that may identify a treatable form of the disease. Of particular interest is a new approach to therapy that uses . . . [Full Text of this Article]




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