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Previous Volume 328:1781-1782 June 17, 1993 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Osteoporosis is the most serious side effect of long-term corticosteroid therapy. The bone mass in corticosteroid-treated patients is reduced in the forearm, spine, and proximal femur, with more loss in trabecular than in cortical bone. The bone mass lost varies from 10 to 40 percent, depending on the site examined, the dose and duration of corticosteroid therapy, the particular corticosteroid used, and the disease treated. The tendency of corticosteroids to damage trabecular bone more than cortical bone is reflected in the greater loss of lumbar mineral density assessed in the lateral projection than in the anteroposterior projection¹. More important, . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Struijs, A., Smals, A., de Witte, S. A., Hackeng, W. H. L., Mulder, H. (2000). Acute effects of etidronate on glucocorticoid-induced bone degradation. Rheumatology (Oxford) 39: 523-529 [Abstract] [Full Text]  
• Odell, W. D. (1996). Testosterone Treatment of Men Treated With Glucocorticoids. Arch Intern Med 156: 1133-1134 [Abstract]  
• LANE, J. M., RILEY, E. H., WIRGANOWICZ, P. Z. (1996). Instructional Course Lectures, The American Academy of Orthopaedic Surgeons - Osteoporosis: Diagnosis and Treatment*{{dagger}}. JBJS 78: 618-32 [Full Text]  
• Arden, N.K., Spector, T.D. (1993). Oestrogens, Bones Systemic Lupus Erythematosus. Lupus 2: 381-382  
• (1993). CALCITRIOL PLUS CALCIUM PREVENTS STEROID-INDUCED BONE LOSS. JWatch General 1993: 4-4 [Full Text]