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Correspondence
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Volume 328:211 January 21, 1993 Number 3
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Office-Based Test Systems for HIV Antibody

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To the Editor: The Food and Drug Administration has approved two assays for human immunodeficiency virus (HIV) antibody for use by "properly trained personnel" in physicians' offices, clinics, emergency rooms, and other settings "where enzyme immunoassays are not practical or available." The indirect immunofluorescence and microfiltration enzyme immunoassays are available for purchase and use in a wide variety of contexts, yet their use raises serious concern about clinical or operational feasibility and about their effect on disease-surveillance programs and preventive intervention.

With respect to clinical usefulness, although the test systems are accompanied by manufacturers' inserts indicating a need for retesting . . . [Full Text of this Article]

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More on Office-Based Testing for HIV
Frerichs R. R., Seymour E., Mucke H. A.M., Haushofer A., Gellert G., Moore D. F., Greenwood R., Maxwell R. M., Weismuller P. C.
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N Engl J Med 1993; 328:1717-1718, Jun 10, 1993. Correspondence

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