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Previous Volume 328:355-356 February 4, 1993 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Zec et al. (June 25 issue)¹ describe a suspected adverse drug reaction (with seizures and acute renal failure) to povidone-iodine used for mediastinal irrigation and suggest that an elevated serum iodine level was responsible. They cite the occurrence of seizures with iodinated contrast agents as supporting evidence.

Although elevated serum iodine levels may cause these events, the chronology leaves unanswered questions. The authors state that renal failure developed "coincident" with the seizure. We are not provided with measurements of blood urea nitrogen and creatinine to assess the pathophysiologic features of the impaired renal function. We are not . . . [Full Text of this Article]

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