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Previous Volume 328:445-446 February 11, 1993 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Cobb et al. (Oct. 8 issue)¹ reported on a trial of scheduled replacement of central venous catheters that compared catheter replacement after three days at a new puncture site with replacement using guide-wire-assisted exchanges. The authors found an increased incidence of catheter colonization and catheter-related bloodstream infection among the patients who underwent guide-wire-assisted catheter exchanges. In addition, they found more catheter-related mechanical complications, such as pneumothorax, among the patients who had catheter replacement at a new puncture site.

Unfortunately, the patients of Cobb et al. underwent catheter insertion principally through the subclavian and internal jugular veins. Central . . . [Full Text of this Article]

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