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Previous Volume 328:451 February 11, 1993 Number 6 Next

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Second edition. Edited by Gary P. Wormser. 715 pp., illustrated. New York, Raven Press, 1992. $130. ISBN 0-88167-881-3.

In keeping with the rapid changes in our knowledge of the biology of HIV, its pathophysiology, and the treatment and prevention of AIDS, the second edition of this book contains several new chapters. A few chapters from the first edition (for example, those on the history of AIDS and ultrastructural changes in AIDS) have been appropriately deleted. The new chapters include a review of viral cofactors in the pathogenesis of HIV, biological features of HIV type 2 (HIV-2), simian retroviruses, gastrointestinal, oral, and ophthalmologic manifestations of AIDS, vaccination and immunization, occupational issues related to AIDS, and ethical issues for research.

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