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Correction to Moore et al., N Engl J Med 327(25):1774-1778 December 17, 1992.

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Volume 329:63 July 1, 1993 Number 1
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Plasma Endothelin and the Hepatorenal Syndrome

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by Moore, K.
To the Editor: Moore et al. (Dec. 17 issue)1 reported that plasma endothelin concentrations were elevated in patients with the hepatorenal syndrome, but they provided no data indicating that endothelin may cause the renal dysfunction. Was the glomerular filtration rate or renal blood flow measured in these patients, and if so, what was the correlation between the results and the plasma endothelin concentrations? I would also like to know the results of measurements of plasma endothelin and renal function in patients with the hepatorenal syndrome who received liver transplants. Longitudinal studies of plasma endothelin concentrations in patients with liver disease . . . [Full Text of this Article]



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