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Previous Volume 329:1043-1045 September 30, 1993 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Materson, B. J. Related Article by Zehender, M.

To the Editor: Materson and colleagues (April 1 issue)¹ compared the effects of six different antihypertensive agents in patients with mild-to-moderate hypertension. Their findings contrast with the results of a similar study comparing five single agents with placebo: the Treatment of Mild Hypertension Study². In that study, no differences were observed in diastolic blood pressure with the five drugs -- acebutolol, amlodipine, chlorthalidone, doxazosin, and enalapril. For systolic blood pressure, the only difference observed was that the diuretic agent (chlorthalidone) was more effective than the alpha-adrenoceptor antagonist (doxazosin) in reducing pressure.

The different findings of the two studies highlight . . . [Full Text of this Article]

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