The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Correspondence
PreviousPrevious
Volume 329:1206 October 14, 1993 Number 16
NextNext

Failure of Mefloquine Chemoprophylaxis for Malaria in Somalia

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited

More Information
To the Editor: A weekly dose of 250 mg of mefloquine (Lariam) is being used by U.S. forces for chemoprophylaxis against malaria in Somalia. We report two cases of malaria caused by Plasmodium falciparum in U.S. soldiers who were taking mefloquine.

A 23-year-old man was admitted on March 3, 1993, with a seven-day history of fever, chills, and headache. A blood smear showed P. falciparum. The serum mefloquine level in blood drawn when the patient's smear was positive was 1067 ng per milliliter for the parent compound and 4014 ng per milliliter for the primary metabolite. He had been taking . . . [Full Text of this Article]

References



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.