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Previous Volume 329:1476-1483 November 11, 1993 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Migraine is an episodic headache that is unilateral or bilateral, pulsating in quality, moderate to severe in intensity, and exacerbated by physical activity. Associated symptoms include nausea or vomiting, photophobia, and phonophobia. The disorder is classified as migraine with aura (previously called classic migraine) and migraine without aura (previously called common migraine), according to the presence or absence, respectively, of premonitory neurologic symptoms¹.

The pathophysiology of migraine is clearly related to disordered brain physiology, although neither the details nor the cause is known. The positive (stimulative) followed by negative (suppressive) neurologic symptoms of the aura and the slow spread . . . [Full Text of this Article]

Symptomatic Treatment of Acute Migraine

Analgesic Drugs

Nonsteroidal Antiinflammatory Drugs

Ergot Preparations

Sumatriptan

Mechanisms of Action of Sumatriptan and Ergotamine

Dopamine Antagonists

Choice of Symptomatic Treatment

Prevention of Migraine

5-HT-Influencing Drugs

Beta-Adrenergic Antagonists

Calcium-Channel-Blocking Drugs

Nonsteroidal Antiinflammatory Drugs

Miscellaneous Drugs

Hormonal Therapy

Conclusion

Source Information

From the Department of Neurology, Henry Ford Hospital and Health Sciences Center, K-11, 2799 W. Grand Blvd., Detroit, MI 48202, where reprint requests should be addressed to Dr. Welch.

References

Related Letters:

Drug Therapy of Migraine
Lahad A., Friedman J. B., Mignot G., Kopp C., Welch K.M.A.
Extract | Full Text  
N Engl J Med 1994; 330:1015-1016, Apr 7, 1994. Correspondence

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