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A correction has been published: N Engl J Med 1994;330(6):448.

Review Article
Medical Progress
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Volume 329:1550-1559 November 18, 1993 Number 21
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Cancer of the Ovary
Stephen A. Cannistra

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Epithelial cancer of the ovary is the fifth most common malignant condition among women in the United States, with an annual incidence of 22,000 new cases1. This disease predominantly affects postmenopausal women in their sixth decade, accounting for approximately 13,300 deaths each year and for over half of all deaths from genital cancer. The highly lethal nature of this tumor is related to the absence of symptoms in the majority of women with early stages of the disease. Seventy percent of women present with advanced disease in which the tumor has spread to the peritoneal surfaces of the upper . . . [Full Text of this Article]

Risk Factors for Ovarian Cancer

Clinical Presentation

Staging and Surgical Treatment

Postoperative Treatment

Limited Disease (Stages I and II)

Advanced Disease (Stages III and IV)

Methods to Obtain a Complete Pathological Response in Advanced Ovarian Cancer

Treatment Options for Persistent or Recurrent Disease

Secondary Debulking Surgery

Intraperitoneal Chemotherapy

Radiotherapy

Systemic, Non-Cross-Resistant Chemotherapy

Autologous Bone Marrow Transplantation

Summary and Future Directions


Source Information

From the Division of Medical Oncology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston.

Address reprint requests to Dr. Cannistra at the Dana-Farber Cancer Institute, 44 Binney St., Boston, MA 02115.

References


Related Letters:

Cancer of the Ovary
Lurain J., McKay M. J., Bull C. A., Collazos J., Embil J. M., Cannistra S. A.
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N Engl J Med 1994; 330:1012-1014, Apr 7, 1994. Correspondence

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