A 25-year-old, previously healthy white man consulted his physicianbecause of a two-month history of progressive diffuse jointpain. Initially, the patient noticed pain in his left elbowon awakening. The pain soon involved both knees and ankles andpersisted for longer periods during the day; it then becameconstant and was accompanied by fatigue. One month after theonset of joint pain, low back stiffness developed, which wasworse on awakening, improved with activity, and increased againat the end of the day. The physical examination was unremarkable.The erythrocyte sedimentation rate was 20 mm per hour, the white-cell. . . [Full Text of this Article]
Commentary
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From the Divisions of Clinical Decision Making and General Internal Medicine, New England Medical Center, Tufts University School of Medicine, Boston.
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References
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