Although the inclusion of women and minorities in medical researchis necessary for valid inferences about health and disease inthese groups, both women and members of minority groups havebeen excluded from or underrepresented in many clinical trials.Congress has therefore proposed that the National Institutesof Health (NIH) ensure that all federally funded clinical researchinclude a valid analysis to determine whether the interventionunder study affects women or members of minority groups differentlyfrom other subgroups. In particular, Section 429B of the NIHRevitalization Act1 provides that the director of the NIH shallensure that women and . . . [Full Text of this Article]
Participation of Women in Clinical Trials
Have Women Been Excluded or Underrepresented?
Barriers to the Full Participation of Women in Clinical Trials
Homogeneity versus Heterogeneity
Interpretation of an Unexpected Difference between Men and Women
Conclusions
Source Information
This article is a synopsis of a white paper written by the Board on Health Sciences Policy. Copies of the white paper are available from the Division of Health Sciences Policy, Institute of Medicine, National Academy of Sciences, 2101 Constitution Ave., Washington, DC 20418.
Address reprint requests to Dr. Ruth Ellen Bulger at the Division of Health Sciences Policy, Institute of Medicine, National Academy of Sciences, 2101 Constitution Ave., FO 3018, Washington, DC 20418.
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