Autosomal dominant polycystic kidney disease is one of the mostcommon hereditary disorders, being 10 times more common thansickle cell disease, 15 times more common than cystic fibrosis,and 20 times more common than Huntington's disease. In addition,the disease accounts for 8 to 10 percent of the cases of end-stagerenal disease, for which medical care costs exceed $200 milliona year. The name previously given to the disorder, "adult polycystickidney disease," belies its true scope by focusing on the kidneyand by confining the disorder to adults. In fact, autosomaldominant polycystic kidney disease is a . . . [Full Text of this Article]
Genetics
Pathogenesis
Epidemiology and Methods of Diagnosis
Renal Manifestations
Complications
Extrarenal Manifestations
Conclusions
Source Information
From the Department of Medicine, Box C-283, University of Colorado Health Sciences Center, 4200 E. Ninth Ave., Denver, CO 80262, where reprint requests should be addressed to Dr. Gabow.
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