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Previous Volume 329:363 July 29, 1993 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Liver transplantation has been performed in a few children with inborn errors of metabolism that do not cause liver failure but may be responsible for severe disease of extrahepatic organs (e.g., Crigler-Najjar syndrome type I). Liver transplantation has restored the correct metabolic pathway in such patients¹.

We report on the correction of the metabolic abnormalities of phenylketonuria in a 10-year-old boy from Italy. The child required orthotopic liver transplantation because of concomitant, unrelated end-stage chronic liver disease. Phenylketonuria had been diagnosed in the neonatal period; it was immediately treated by restriction of dietary phenylalanine. Satisfactory control . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Levy, H. L. (1999). Phenylketonuria: Old disease, new approach to treatment. Proc. Natl. Acad. Sci. USA 96: 1811-1813 [Full Text]