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Books devoted entirely to a comprehensive study of sickle cell anemia are few in number, so a new book is to be welcomed. As in many multiauthored books, the chapters vary in quality and usefulness and tend to be repetitive in their introductions, but on the whole the editors have made a good choice of topics and authors.
The first 198 pages deal with basic aspects of genetics, biochemistry of sickling, pathophysiology of sickle syndromes, and anatomical pathology. The pathological chapter, by Dr. Lemuel W. Diggs, the most knowledgeable expert on the subject, is extensively illustrated with gross and microscopical
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